- Nuclear Materials and Properties
- Fusion materials and technologies
- High-Temperature Coating Behaviors
- High Entropy Alloys Studies
- Advanced Image and Video Retrieval Techniques
- Video Surveillance and Tracking Methods
- Nuclear materials and radiation effects
- Robotics and Sensor-Based Localization
- Nuclear reactor physics and engineering
- Advanced Neural Network Applications
- Drug Transport and Resistance Mechanisms
- Advanced materials and composites
- Advanced ceramic materials synthesis
- Advanced Vision and Imaging
- Domain Adaptation and Few-Shot Learning
- Pharmacological Effects and Toxicity Studies
- Analytical Chemistry and Chromatography
- Ion-surface interactions and analysis
- Cellular transport and secretion
- Intermetallics and Advanced Alloy Properties
- Hops Chemistry and Applications
- Hydrogen embrittlement and corrosion behaviors in metals
- Mass Spectrometry Techniques and Applications
- Food composition and properties
- Polysaccharides Composition and Applications
Chongqing University
2024
Agilent Technologies (United States)
2020-2024
Jiangnan University
2022-2024
University of Nottingham Ningbo China
2024
State Key Laboratory of Food Science and Technology
2022-2024
China General Nuclear Power Corporation (China)
2018-2024
China Southern Power Grid (China)
2024
Sichuan Agricultural University
2024
Second Affiliated Hospital of Zhejiang University
2022-2024
Zhejiang University
2022-2023
Few-shot object detection, which aims at detecting novel objects rapidly from extremely few annotated examples of previously unseen classes, has attracted significant research interest in the community. Most existing approaches employ Faster R-CNN as basic detection framework, yet, due to lack tailored considerations for data-scarce scenario, their performance is often not satisfactory. In this paper, we look closely into conventional and analyze its contradictions two orthogonal...
Scope Women seeking alternatives to hormone‐replacement therapy for menopausal symptoms often try botanical dietary supplements containing extracts of hops ( Humulus lupulus L.). Hops contain 8‐prenylnaringenin (8‐PN), a potent phytoestrogen, the related flavanones 6‐prenylnaringenin and isoxanthohumol (IX), prenylated chalcone xanthohumol (XN). Methods results After chemically biologically standardizing an extract spent these marker compounds, escalating dose study was carried out in women...
Most of the few-shot learning methods learn to transfer knowledge from datasets with abundant labeled data (i.e., base set). From perspective class space on set, existing either focus utilizing all classes under a global view by normal pretraining, or pay more attention adopt an episodic manner train meta-tasks within few in local view. However, interaction two views is rarely explored. As capture complementary information, we naturally think compatibility them for achieving further...
Vectorized high-definition map (HD-map) construction, which focuses on the perception of centimeter-level environmental information, has attracted significant research inter-est in autonomous driving community. Most existing approaches first obtain rasterized with segmentation-based pipeline and then conduct heavy post-processing for downstream-friendly vectorization. In this paper, by delving into parameterization-based methods, we pioneer a concise elegant scheme that adopts unified...
Vectorized high-definition map online construction has garnered considerable attention in the field of autonomous driving research. Most existing approaches model changeable elements using a fixed number points, or predict local maps two-stage autoregressive manner, which may miss essential details and lead to error accumulation. Towards precise element learning, we propose simple yet effective architecture named PivotNet, adopts unified pivot-based representations is formulated as direct...
Current approved chimeric antigen receptor (CAR) T-cell products are autologous cell therapies that costly and poorly accessible to patients. We aimed evaluate the safety antitumor activity of a novel off-the-shelf anti-CD19 CAR-engineered allogeneic double-negative T cells (RJMty19) in patients with relapsed/refractory large B-cell lymphoma. report results from first-in-human, open-label, single-dose, phase 1 study CD19-specific CAR (CAR-DNT) cells.
ABSTRACT Hepatic uptake transport is often the rate‐determining step in systemic clearance of drugs. The ability to predict and determine contribution individual transporters overall hepatic therefore critical assessing potential pharmacokinetic pharmacodynamic variability associated with drug–drug interactions pharmacogenetics. present study revisited interaction statin drugs, including pitavastatin, fluvastatin rosuvastatin, sodium‐dependent taurocholate co‐transporting polypeptide (NTCP)...
As a canalicular bile acid effluxer, the salt export pump (BSEP) plays vital role in maintaining homeostasis. BSEP deficiency leads to severe cholestasis and hepatocellular carcinoma (HCC) young children. Regardless of etiology, chronic inflammation is common pathological process for HCC development. Clinical studies have shown that homeostasis disrupted patients with elevated serum level as proposed marker HCC. However, underlying mechanisms remain largely unknown. In this study, we found...
The contribution of organic anion transporter OAT2 (SLC22A7) to the renal tubular secretion creatinine and its exact localization in kidney are reportedly controversial. In present investigation, transport was assessed human embryonic (HEK) cells that stably expressed (OAT2-HEK) isolated proximal tubule (HRPTCs). human, monkey, rat characterized. overexpression significantly enhanced uptake OAT2-HEK cells. Under physiologic conditions (creatinine concentrations 41.2 123.5 <i>µ</i>M), initial...
Six kinds of FeCrAl coatings with different Cr and Al contents were irradiated by 6 MeV Au-ions a damage level 20 dpa. The results showed that the surface roughness grain size increased significantly after irradiation. Nanoscale precipitation irradiation-induced twins appeared in coating relatively lower content. increase content promotes transformation from softening to hardening. Changed can cause change hardness, but cannot transition underlying evolution mechanism microstructure...
FeAl/Al2O3 coatings, candidate coating materials for lead-cooled fast reactors, are first irradiated to produce pre-defects and then subjected lead–bismuth eutectic corrosion simulate the performance in coupled field of irradiation corrosion. Irradiation causes voids outer Al2O3 layer resulting swelling lattice distortion dislocations inner FeAl compressive strain intercrystalline void expansion. The weakened coatings crack during suffer from Pb, Bi, O penetration, causing internal...
The research on Chinese steamed bread (CSB) with whole wheat flour (WWF) is limited and has not been discussed during freeze-thaw. This study investigated the effects of WWF addition dough CSB quality freeze-thaw cycles. results low-field nuclear magnetic resonance (LF-NMR) dynamic rheological properties demonstrated that reduced adverse changes treatment dough. Characteristics, texture, cross section analysis showed (20%) could relatively maximize stability. To mechanism, arabinoxylan (AX)...
Inhibitors of quinone reductase-2 (NQO2; QR-2) can have antimalarial activity and antitumor activities or function as chemoprevention agents by preventing the metabolic activation toxic quinones such menadione. To expedite search for new natural product inhibitors QR-2, we developed a screening assay based on ultrafiltration liquid chromatography−mass spectrometry that is compatible with complex samples bacterial botanical extracts. Human QR-2 was prepared recombinantly, known inhibitor,...
A comprehensive evaluation including microstructure, mechanical properties, and lead-bismuth eutectic corrosion resistance of amorphous alumina coatings after different doses Au2+ irradiation was done using X-ray diffraction, scanning electron microscopy, transmission nanoindentation, SRIM software, eRDF Analyzer. The results showed that decreased the surface roughness induced crystallization in middle coating at interface. might be dominated by energy loss, while interface had to consider...