A5049196256- Glycosylation and Glycoproteins Research
- Neuroscience and Neuropharmacology Research
- Blood Pressure and Hypertension Studies
- Protein Tyrosine Phosphatases
- Galectins and Cancer Biology
- Neurogenesis and neuroplasticity mechanisms
- Cell Adhesion Molecules Research
- Lysosomal Storage Disorders Research
- Helicobacter pylori-related gastroenterology studies
- Healthcare Systems and Technology
- Peptidase Inhibition and Analysis
- Cancer Genomics and Diagnostics
- Health and Medical Education
- Health and Medical Research Impacts
- Cancer, Hypoxia, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Non-Invasive Vital Sign Monitoring
- Cardiac Health and Mental Health
- Intracranial Aneurysms: Treatment and Complications
- Signaling Pathways in Disease
- Glioma Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Hemodynamic Monitoring and Therapy
- Vascular Malformations Diagnosis and Treatment
- Health and Lifestyle Studies
American University of Beirut Medical Center
2025
San Sebastián University
2020-2022
Fundación Ciencia and Vida
2022
Ministry of Health
2022
Pontificia Universidad Católica de Chile
2019-2020
Reoperation for patients with recurrent glioblastoma multiforme (GBM) is a highly debated topic within the medical community. GBM known its aggressive nature and poor prognosis, most experiencing tumor recurrence despite initial treatments. Some studies suggest survival benefit from second surgery, while others do not. The aim of this study to assess whether reoperation offers compared who not undergo re-resection identify prognostic factors influencing patient selection reoperation. This...
<title>ABSTRACT</title> Hypertension (arterial blood pressure ≥ 140/90 mmHg) is a risk factor for cardiovascular diseases, with the greatest burden of attributable deaths in Chile, having national prevalence 27.6%. In 2018, implementation HEARTS begun primary health care centers Public Health System, aim achieving increase control rates, by raising proportion hypertensive individuals who meet goals (< mmHg 15–79 years old and 150/90 80 older), thus contributing to reduce morbidity...
Abstract Background and Objective During cyclosporine‐induced gingival overgrowth, the homeostatic balance of connective tissue is disrupted leading to fibrosis. Galectins are glycan‐binding proteins that can modulate a variety cellular processes including fibrosis in several organs. Here, we study role galectin‐8 (Gal‐8) response cells cyclosporine. Methods We used human fibroblasts mouse NIH3T3 treated with recombinant Gal‐8 and/or cyclosporine for analyzing specific mRNA protein levels...
Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate this and have neuropathogenic effects that are mediated by cross-reacting neuronal surface antigen (NSPA) protein. Elucidating function of NSPA can then reveal CD pathogenic mechanisms treatment opportunities. In brain, somehow contributes to glutamatergic NMDA receptor (NMDAR) activity in synaptic plasticity memory. Here we analyze...
Colorectal (CRC) is one of the most common types cancer worldwide. Most tumors develop from an adenoma in a period 10 to 15 years, but some may appear without previous adenomatous lesions. Seventy-five percent colorectal cancers are sporadic, 20% have family component (first or second-degree relatives with CRC) and 5% hereditary predisposition Mendelian pattern. The epidemiological evolution recent years Chile has worrisome treatment costs advanced stages burden for healthcare system. We...
<title>RESUMEN</title> <sec> <title>Objetivo.</title> Describir los tipos de dispositivos medición presión arterial comercializados a través la plataforma Mercado Público entre años 2018 y 2020. </sec> <title>Métodos.</title> Estudio tipo descriptivo procedente las transacciones realizadas en el periodo 2020, para adquisición arterial. Para equipos automáticos, se buscó estado validación otorgado por organismos internacionales. Los resultados presentan frecuencias absolutas relativas....
Cancer constitutes the second most common cause of death worldwide and is expected to become leading one, even above cardiovascular diseases. The understanding cellular molecular basis cancer has led not only proper development chemotherapy but also target therapies. Although these advances are related with improved survival rates among patients, it poorly impacted its incidences. In this regard, lack knowledge regarding impact that several carcinogenic factors their interactions have on...