A5025343420- Hematopoietic Stem Cell Transplantation
- Acute Myeloid Leukemia Research
- Polyomavirus and related diseases
- Renal Transplantation Outcomes and Treatments
- Chronic Myeloid Leukemia Treatments
- Blood groups and transfusion
- Retinal Diseases and Treatments
- MicroRNA in disease regulation
- Multiple Myeloma Research and Treatments
- Immune cells in cancer
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Coconut Research and Applications
- Head and Neck Cancer Studies
- Public Administration and Political Analysis
- Viral-associated cancers and disorders
- Consumer Attitudes and Food Labeling
- Food composition and properties
- Long-Term Effects of COVID-19
- Circular RNAs in diseases
- Microbial infections and disease research
- Neutropenia and Cancer Infections
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Oral health in cancer treatment
- Pneumonia and Respiratory Infections
- Retinal and Optic Conditions
Jena University Hospital
2007-2023
Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie
2015
Center for Clinical Studies
2010
University Hospital of Zurich
2005
Friedrich Schiller University Jena
2004-2005
University Hospital Magdeburg
2003
Allogeneic hematopoietic stem cell transplantation for chronic granulomatous disease (CGD) is associated with a significant risk of transplant-related mortality. Adult age, overt infection, and residual inflammatory at transplant are major factors.Here we report the favorable outcome after bone marrow in three high-risk adult CGD patients (ages 18, 35, 39) severe disease-related complications (overt pneumonia, liver abscess, steroid-dependent colitis, diabetes, restrictive lung disease,...
Abstract Introduction Following SARS‐CoV‐2‐infection up to 21% of patients will develop post‐COVID‐syndrome. Autoantibodies (AAbs) targeting neuronal‐ß‐adrenergic and muscarinic receptors may provide crucial contributions the pathophysiology this condition. Immunoadsorption (IA) has been identified as an effective means removing AAbs resulted in clinical improvements other autoantibody‐associated diseases. Methods We determined AAb‐levels (anti‐ß1/ß2 anti‐M3/M4 receptor) 178 diagnosed with...
Background Regular consumption of the soluble dietary fiber β-glucan is associated with decreased total cholesterol (TC), low-density lipoprotein (LDL) and blood glucose. Barley oat flakes as natural sources were roasted to improve sensory quality. The aim this study was investigate whether roasting barley changes physiological impact β-glucan-rich on glucose lipid metabolism. Method A five-armed randomized crossover trial design used. intervention conducted from May 2018 2019 included 32...
The Epstein-Barr virus (EBV) produces different microRNAs (miRNA) with distinct regulatory functions within the infectious cycle. These viral miRNAs regulate expression of and host genes have been discussed as potential diagnostic markers or even therapeutic targets, provided that profile can be unambiguously correlated to a specific stage infection EBV-induced disorder. In this context, miRNA profiling becomes more important since roles these in pathogenesis infections malignancies are not...
Abstract Background Community‐acquired respiratory viruses (CARV) cause upper and lower tract infections (URTI/LRTI) may be life‐threatening for recipients of an allogeneic stem cell transplantation (allo‐SCT). Methods In a prospective study encompassing 4 winter‐seasons, we collected throat gargles (TG) at random time points from allo‐SCT (patients) controls followed them up least 3 weeks including repetitive sampling documentation symptoms. A Multiplex‐PCR system to identify 20 CARV...
Relapse after anthracycline based combination chemotherapy is frequently seen in patients with aggressive non Hodgki n's Lymphomas (NHL), whereas complications such as secondary leukemia or solid tumor rarely occur. We report a patient diffuse large cell (DLC) NHL and concurrent renal cancer, who developed acute myelofibrosis (AMF) later the course of her disease. This 60-year-old female presented pancytopenia right sided mass. Diagnostic work up revealed severe bone marrow infiltration by...
Abstract: The Spectra Optia ® Apheresis System is an automatic blood component separator used to perform various therapeutic apheresis procedures, cell collection and processing procedures. Users could follow all instructions given by the SPO secure comfortable. However, there are no formal guidelines for use of specific devices in apheresis. focus this review application apheresis, its clinical risks benefits. Although only few data exist evaluating System, it can be said that device safe...