A5068599638- Endometrial and Cervical Cancer Treatments
- Colorectal and Anal Carcinomas
- Lymphoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Advanced Radiotherapy Techniques
- Metastasis and carcinoma case studies
- Cervical Cancer and HPV Research
- Breast Cancer Treatment Studies
- Colorectal Cancer Surgical Treatments
- Multiple and Secondary Primary Cancers
- Ovarian cancer diagnosis and treatment
- Pituitary Gland Disorders and Treatments
- CNS Lymphoma Diagnosis and Treatment
- CAR-T cell therapy research
- MRI in cancer diagnosis
- Gastric Cancer Management and Outcomes
- Medical Imaging Techniques and Applications
- Myasthenia Gravis and Thymoma
- Inflammasome and immune disorders
- Sarcoma Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Ultrasound and Hyperthermia Applications
- Traditional Chinese Medicine Analysis
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025
Shanghai Jiao Tong University
2025
Peking Union Medical College Hospital
2016-2023
Shandong First Medical University
2023
Shandong Tumor Hospital
2023
National Clinical Research
2019
Shantou University
2011
First Affiliated Hospital of Shantou University Medical College
2011
Shanghai Ninth People's Hospital
1989
Abstract Background and Objectives microRNAs (miRNAs), small non‐coding RNAs, are always aberrantly expressed in many diseases including human cancers. The aim of this study was to examine determine the clinical significance hsa‐miR‐31, hsa‐miR‐142‐3p, hsa‐miR‐338‐3p, hsa‐miR‐1261 expression esophageal squamous cell carcinoma (ESCC). Methods Expression levels four selected miRNAs, initially evaluated by microarray, were validated qRT‐PCR. Various statistical methods used analyze relationship...
The dried rhizome of Notopterygium incisum (NI) from the Umbelliferae family, genuinely produced in Sichuan, China, is a classic traditional Chinese medicinal herb for treating wind-dampness arthralgia. Due to scarce natural resources, wild NI gradually being replaced by cultivated types. However, knowledge limited regarding differences chemical composition and pharmacological effects between Sichuan-grown other-region-grown NI. In this study, plant metabolomics strategy, based on GC–MS...
Polycatenanes, a novel class of polymers consisting interlocked macrocyclic monomers, have attracted significant attention. However, the formation mechanism polycatenanes through direct catenation remains poorly understood. Herein we explore structural diversity and unique chain termination inherent to polycatenanes. Unlike conventional linear polymers, polycatenane exhibits variety topological configurations, with growth terminated upon completely interwoven structures. This intrinsic...
Background: The survival outcomes of patients with relapsed/refractory (R/R) primary central nervous system lymphoma (PCNSL) remain extremely poor and there are no approved therapies or widely accepted "standard-of-care" approaches. Previous studies showed that Bruton tyrosine kinase (BTK) inhibitor anti-programmed death protein-1(PD-1) monoclonal antibody have significant activities in R/R PCNSL, respectively. combination BTK anti-PD-1 demonstrated synergistic effects both vivo vitro...
Background: Systemic lupus erythematosus (SLE) is one of the most common auto-immune diseases in childhood. Primary immunodeficiency disease (PID) patients may present or combine with autoimmune diseases. Objectives: This study aimed to perform gene sequencing via high-throughput technology a series Chinese pediatric SLE patients, and investigate concomitant situation PIDs SLE. Gene results help clarify pathogenesis Methods: was retrospective case children who referred Peking Union Medical...
Randomized trials testing hypofractionated radiation therapy (HFRT) after breast conservative surgery have reported similar efficacy and toxicity compared with conventional fractionated (CFRT). To evaluate the of HFRT mastectomy, we conducted a phase III randomized trial in June 2008, interim analysis enrolled patients was here. Breast cancer who had 4 or more positive nodes and/or tumor size than 5 cm were randomly assigned mastectomy to 50 Gy 25 fractions over weeks (CFRT) versus 43.5 15 3...
Background: Familial cold autoinflammatory syndrome 3 (FCAS3) is an disease (AID) caused by mutation of the PLCG2 gene, which has not been reported in China. We will report 2 cases Chinese FCAS3 patients with no claimed family history, but we found same mutations a parent during their genetic analysis. After further inquiry parent’s medical confirmed that actually, they were two families. Through literature review, clinical features are milder than foreign countries, and symptoms concealed...