A5047329150- Animal Virus Infections Studies
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- Electrolyte and hormonal disorders
- Virus-based gene therapy research
- Nitric Oxide and Endothelin Effects
- Blood groups and transfusion
- Viral Infections and Immunology Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Potassium and Related Disorders
- Metabolism and Genetic Disorders
- Growth Hormone and Insulin-like Growth Factors
- Renal function and acid-base balance
- Diabetes Management and Research
- Vector-Borne Animal Diseases
- Virology and Viral Diseases
- Mitochondrial Function and Pathology
- TGF-β signaling in diseases
- Milk Quality and Mastitis in Dairy Cows
- Mycobacterium research and diagnosis
- Poxvirus research and outbreaks
- Blood disorders and treatments
- Electrochemical Analysis and Applications
- Sodium Intake and Health
Norwegian University of Science and Technology
2025
Universidade do Porto
2008-2023
Heinrich Heine University Düsseldorf
1995-2020
Institute of Biomedical Science
2018-2019
University of Bonn
2019
Friedrich-Alexander-Universität Erlangen-Nürnberg
2009-2019
University Medical Center Freiburg
2019
University of Freiburg
2019
Robert Koch Institute
2019
University of Würzburg
2019
The pattern of secretion plasma ACTH, hGH, TSH, LH, FSH and cortisol was studied in 12 menstrual cycles, representing 5 normal volunteers. Results were plotted by taking the LHFSH midcycle peak as day 0. typical cyclic LH observed each case. hGH varied significantly throughout cycle. ACTH characterized a decrease during follicular phase, nadir at −2, followed significant increase to 0, then subsequent constant levels luteal phase until +8. Cortisol lowest −4, highest from −2 today During...
In several vertebrate species, Borna disease virus (BDV), the prototype of a new group animal viruses, causes central nervous system accompanied by diverse behavioral abnormalities. Seroepidemiological data indicate that BDV may contribute to pathophysiology certain human mental disorders. This hypothesis is further supported detection both antigens and RNA in peripheral blood mononuclear cells (PBMCs) patients with psychiatric disorders isolation from such PBMCs. Here we describe...
ABSTRACT The ability to maintain running economy is generally evaluated during a long continuous exercise bouts, and it unclear whether the menstrual cycle phase acts as confounder. first aim of this study was evaluate typical 1‐h low‐ (LIT) high‐intensity training (HIT) sessions in female athletes. second investigate affected economy. Naturally menstruating endurance‐trained females performed three LIT ( n = 16) (45%–55% maximal velocity achieved incremental test) and/or HIT 17) (5 × 4 min...
Canine parvovirus (CPV) has been evolving, generating new genetic and antigenic variants throughout the world. This study was conducted to determine types of CPV circulating in dogs Figueira da Foz, Portugal. Thirty fecal samples, collected between 2006 2007 from with clinical signs infection, were tested for by a rapid, in-clinic, enzyme-linked immunosorbent assay (ELISA)/immunomigration test, conventional real-time polymerase chain reaction (PCR), minor-groove binding TaqMan PCR. Of 29...
Serologic evidence for canine distemper virus (CDV) has been described in grey wolves but, to our knowledge, strains circulating have not characterized genetically. The emergence of CDV several non-dog hosts associated with amino acid substitutions at sites 530 and 549 the hemagglutinin (H) protein. We sequenced H gene wild-type obtained from two free-ranging Iberian (Canis lupus signatus) one domestic dog familiaris). More differences were found between wolf sequences than (wolf 75) dog....
Background: Since 2008 patients with BH4-sensitive phenylketonuria can be treated sapropterin dihydrochloride (Kuvan®) in addition to the classic phenylalanine (Phe) restricted diet. The aim of this study was evaluate nutritional changes and micronutrient supply (PKU) under therapy tetrahydrobiopterin (BH4). Subjects Methods: 19 children PKU (4–18 years) potential BH4-sensitivity were included, 14 completed protocol. Dried blood Phe concentrations as well detailed dietary records obtained...
Abstract The interaction of sperm with the oocyte is pivotal during process mammalian fertilization. limited numbers that reach fallopian tube as well anatomic restrictions indicate human sperm–oocyte encounter not a matter chance but directed process. Chemotaxis proposed mechanism for re-orientating toward source chemoattractant and hence to oocyte. Chemokines represent superfamily small (8–11 kDa), cytokine-like proteins have been shown mediate chemotaxis tissue-specific homing leukocytes...
We describe the first known case of an algaemia by Prototheca blaschkeae in a dairy cow, which occurred after chronic episode mastitis caused this pathogen. The organism was isolated from milk, joint fluid and blood samples, microbiologic molecular methods were performed to obtain definitive identification algae. affected cow culled only confirmation systemic infection Prototheca.
African swine fever (ASF) is a highly pathogenic viral disease affecting all Suidae, with Ornithodoros moubata complex soft ticks acting as the biological arthropod vectors of causative agent, virus (ASFV). While ASFV also transmissible via direct contact, pig products and fomites, other arthropods may be involved in transmission persistence. Therefore, we checked various groups blood-feeding collected during summer 2017 wild boar habitats on Estonian Island Saaremaa for presence ASFV. had...
In two patients, a 50-year-old woman (case 1) and 2-year-old girl 2) acute shortness of breath requiring artificial ventilation developed 3-5 hours after infusion erythrocyte concentrates in case 1 unfiltered platelet-enriched plasma (20 ml/kg) 2. The chest radiograph showed diffuse infiltrations the lungs both patients. After administration catecholamines respirator therapy, extubation was possible first patient days, second five days. neither had there been any evidence hypervolaemia,...
In 2018, a cluster of pediatric human parechovirus (HPeV) infections in 2 neighboring German hospitals was detected. Viral protein 1 sequence analysis demonstrated co-circulation different HPeV-3 sublineages and HPeV-1 -5 strains, thereby excluding nosocomial outbreak. Our findings underline the need for HPeV diagnostics outbreak investigations.
Colibacillosis is one of the most important diseases in poultry production. The use antimicrobials remains a therapeutic cornerstone for avian pathogenic E. coli (APEC), thereby contributing to development antimicrobial resistance (AMR). aim this study was characterize AMR broiler breeder flocks reared under commercial conditions. Data covering 10 years, from 2009 2018, were used evaluate phenotypic 264 APEC isolates obtained 158 large company Portugal. tested against eleven by Kirby-Bauer...
A workshop was convened, at which seven enzyme-linked immunosorbent assays (ELISAs) were compared with virus isolation for the detection of viraemia in serial blood samples collected from six pigs up to fourteen days after inoculation classical swine fever virus. All ELISAs double antibody sandwich type, using monoclonal and/or polyclonal antibodies detect a variety viral proteins leukocytes, or anti-coagulated serum. Compared isolation, specificity ELISA good: only one sample found negative...
Summary Chemokines receptors are transmembrane proteins that bind chemokines. and their known to play a crucial role in the immune system pathogen entry. There is evidence myxoma virus, causative agent of myxomatosis, can use chemokine receptor CXCR4 infect cells. This virus causes benign disease its natural host, Sylvilagus , but European rabbit ( Oryctolagus cuniculus ) it highly fatal infectious as myxomatosis. We have characterized gene five genera order Lagomorpha, Ochotona...