Carlotta Alias

ORCID: 0000-0003-4808-7363
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Research Areas
  • Carcinogens and Genotoxicity Assessment
  • Pesticide and Herbicide Environmental Studies
  • Environmental Toxicology and Ecotoxicology
  • Recycling and Waste Management Techniques
  • Materials Engineering and Processing
  • Mycotoxins in Agriculture and Food
  • Composting and Vermicomposting Techniques
  • Chemical Safety and Risk Management
  • Heavy metals in environment
  • Wastewater Treatment and Reuse
  • Pesticide Exposure and Toxicity
  • Water Treatment and Disinfection
  • Environmental Justice and Health Disparities
  • Climate Change and Health Impacts
  • Garlic and Onion Studies
  • Molecular Biology Techniques and Applications
  • Cancer, Lipids, and Metabolism
  • Angiogenesis and VEGF in Cancer
  • Chemical Analysis and Environmental Impact
  • Microbial Metabolites in Food Biotechnology
  • Protease and Inhibitor Mechanisms
  • Plant Growth Enhancement Techniques
  • Plant Disease Management Techniques
  • Barrier Structure and Function Studies
  • Uterine Myomas and Treatments

University of Brescia
2018-2025

Surgical Specialties (Canada)
2024

University of Parma
2015

In this study, the agricultural digestate from anaerobic biogas production mixed with food wastes was used as a substrate to grow Trichoderma reesei RUT-C30 and atroviride Ta13 in solid-state fermentation (SSF) produce high-value bioproducts, such bioactive molecules be ingredients for biostimulants. The spp. reached their maximum growth after 6 3 SSF days, respectively. Both species were able cellulase, esterase, citric malic acids, while T. also produced gibberellins oxylipins shown by...

10.1021/acs.jafc.2c07388 article EN cc-by Journal of Agricultural and Food Chemistry 2023-02-03

During experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis associated with blood-brain barrier (BBB) disruption, oligodendrocyte precursor cells (OPCs) overexpress proteoglycan nerve/glial antigen 2 (NG2), proliferate, and make contacts the microvessel wall. To explore whether OPCs may actually be recruited within neurovascular unit (NVU), de facto intervening in its cellular molecular composition, we quantified by immunoconfocal morphometry presence of contact...

10.1371/journal.pone.0213508 article EN cc-by PLoS ONE 2019-03-14

From a circular economy perspective, the recovery and reuse of waste plays fundamental role. Foundries purchase hundreds millions siliceous sands every year to create molds cores that give shape casting. These sands, after several uses, become must be properly recovered or disposed of; they are called foundry (WFS). The WFS leads reduction in: (i) consumption raw materials; (ii) emissions into atmosphere; (iii) amount sent landfill—on other hand, impact their use generates on environment...

10.3390/app12136420 article EN cc-by Applied Sciences 2022-06-24

This study aimed at valorizing digestate through Trichoderma spp. solid-state fermentation (SSF) to produce a potentially ameliorated fertilizer combined with fungal biomass as value-added bioproduct. Plant-growth-promoting atroviride Ta13, T. reesei RUT-C30, asperellum R, and harzianum T-22 were tested on different SSF substrates: whole (WD), dried up wood sawdust (SSF1), enriched food waste (SSF2). The was quantified by using qPCR assay. growth of the four only observed SSF2 substrate....

10.3390/microorganisms10010164 article EN cc-by Microorganisms 2022-01-13

Given the considerable quantities of biogenic matrices employed in agricultural applications, there is growing concern about potential negative effects resulting from presence harmful contaminants. The project "SLURP - SLUdge Recovery Agriculture: Environment and Health Protection" planned a multi-stage approach which application wide battery bioassays was proposed as an effective tool to measure direct interaction with different components ecosystem, molecular whole organism level. aim...

10.1016/j.chemosphere.2025.144175 article EN cc-by Chemosphere 2025-02-20

The application of a battery bioassays is widely recognized as useful tool for assessing environmental hazard samples. However, the integration different toxicity data key aspect this assessment and remains challenge. evaluation industrial waste leachates did not initially undergo any proposed procedures. This research addressed knowledge gap. Twenty-five samples foundry sands were subjected to leaching test (UNI EN 12457-2) evaluate recovery landfill disposal. evaluated using standardized...

10.1002/ieam.4983 article EN cc-by Integrated Environmental Assessment and Management 2024-08-30

Abstract Drinking water quality can be compromised at different stages, from raw to treated one. This research aimed evaluate the toxicity and genotoxicity of groundwater contaminated by fluorinated compounds in a drinking treatment plant, through several bioassays. Water samples underwent chemical analyses were assayed on Daphnia magna , Pseudokirchneriella subcapitata Allium cepa human leukocytes Salmonella typhimurium . Physical–chemical parameters always within Italian legislation...

10.1111/wej.12819 article EN cc-by Water and Environment Journal 2022-08-18

Steel slags, the main waste product from steel industry, may have several reuse possibilities. Among others, building applications represent a crucial field. However, potential impact of harmful substances on environment should be assessed. The aim this study was to assess phytotoxicity slags (SS) and concrete mixtures cast with partial replacement SS (CSS). Leaching tests were carried out four CSS according EN 12457-2 UNI 15863, respectively. Each leachate assayed using root elongation 30...

10.1007/s00128-023-03764-y article EN cc-by Bulletin of Environmental Contamination and Toxicology 2023-06-21

Many fungal genera such as Aspergillus, Penicillium, Fusarium and Alternaria are able to produce, among many other metabolites, the aflatoxins, a group of toxic carcinogenic compounds. To reduce their formation, synthetic fungicides used an effective way intervention. However, extensive use molecules generates long-term residues into food environment. The need new antifungal molecules, with high specificity low off-target toxicity is worth. aim this study was evaluate: i) genotoxicity newly...

10.1016/j.mrgentox.2023.503654 article EN cc-by Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2023-06-30

A low-energy paradigm was adopted for sustainable, affordable, and effective urban waste valorization. Here a new, eco-designed, solid-state fermentation process is presented to obtain some useful bio-products by recycling of different wastes. Urban food scraps from trimmings were used as substrate the production citric acid (CA) solid state Aspergillus niger NRRL 334, with yield 20.50 mg CA per gram substrate. The solution extract metals printed circuit boards (WPCBs), one most common...

10.3390/microorganisms9050895 article EN cc-by Microorganisms 2021-04-22

The potential impact of concrete mixtures containing steel slag (SS) as a partial replacement natural aggregates (NA) on the terrestrial ecosystem was assessed using battery plant-based bioassays. Leaching tests were conducted four and one mixture only NA (reference concrete). Leachates tested for phytotoxicity seeds Lepidium sativum, Cucumis sativus, Allium cepa. Emerging seedlings L. sativum A. cepa used to assess DNA damage (comet test). genotoxicity leachates also analyzed with bulbs...

10.1002/etc.5709 article EN cc-by Environmental Toxicology and Chemistry 2023-07-04

Abstract Steel slags (SS) are the major waste produced by iron and steel industry. Slags may be reused as recycled materials, instead of natural aggregates (NA), to reduce final disposal in a landfill exploitation raw materials. However, reuse SS generate potential release toxic compounds for environment humans. The purpose this study was evaluate toxicity genotoxicity SS, comparison with NA, using an integrated chemical‐biological approach enable their safe engineering applications....

10.1002/em.22407 article EN Environmental and Molecular Mutagenesis 2020-09-24

The European iron and steel industry produces a considerable amount of waste by-products. Also in Italy the slag production is very high. Steel slags may be reused recycled materials, such as materials for construction industry, road base asphalt mixtures, allowing to reduce final disposal landfill. reuse this material generate potential release toxic compounds environment humans. aim study was assess ecotoxicity genotoxicity by using an integrated chemical-biological approach. Chemical...

10.31025/2611-4135/2019.13815 article EN Detritus 2018-01-01

Abstract Gynaecological leiomyosarcoma ( gLMS ) represent a heterogeneous group of soft tissue sarcoma, characterized by rare incidence, high aggressiveness and propensity to infiltrate secondary organs, poor prognosis lethality, because the lack biological mechanisms that underlying their progression effective pharmaceutical treatments. This study was focused on some aspects dissemination subtype namely vulvar LMS vLMS ). We therefore used ‐derived cell line SK ‐ ‐1, coupled with in vitro...

10.1111/jcmm.12565 article EN cc-by Journal of Cellular and Molecular Medicine 2015-05-22

Abstract Steel slags (SS), by-products of the steel industry, may be used as recycled materials. However, their reuse generate potential release harmful compounds into environment. The aim this study was to assess impact concrete mixtures cast with SS partial replacement natural aggregate on terrestrial ecosystem, in terms toxicity and genotoxicity, by using a battery bioassays composed higher plants. Four mixtures, each one aggregates 30% four different mixture only (reference concrete)...

10.21203/rs.3.rs-2041011/v1 preprint EN cc-by Research Square (Research Square) 2022-10-06
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