A5101847947- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Multiple Sclerosis Research Studies
- Retinal Development and Disorders
- Visual perception and processing mechanisms
- Corneal Surgery and Treatments
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Visual Impairment Studies
- Cardiovascular Syncope and Autonomic Disorders
- Lysosomal Storage Disorders Research
- Peripheral Neuropathies and Disorders
- Geography Education and Pedagogy
- Reproductive tract infections research
- Ocular Disorders and Treatments
- ATP Synthase and ATPases Research
- Educational Tools and Methods
- Ethics and Legal Issues in Pediatric Healthcare
- Retinopathy of Prematurity Studies
- Traumatic Ocular and Foreign Body Injuries
- Ophthalmology and Eye Disorders
- Migraine and Headache Studies
- Sympathectomy and Hyperhidrosis Treatments
University of Coimbra
2010-2025
Escola Superior de Tecnologia da Saúde de Coimbra
2025
Hospitais da Universidade de Coimbra
2017-2023
Hospital Garcia de Orta
2017
Hospital Braga
2017
Centro Hospitalar do Porto
2017
Centro Hospitalar de Vila Nova de Gaia
2017
Association for Innovation and Biomedical Research on Light and Image
2008-2013
Columbia Education
2008
Nonophthalmologist physicians do not confidently perform direct ophthalmoscopy. The use of artificial intelligence to detect papilledema and other optic-disk abnormalities from fundus photographs has been well studied.We trained, validated, externally tested a deep-learning system classify optic disks as being normal or having 15,846 retrospectively collected ocular that had obtained with pharmacologic pupillary dilation various digital cameras in persons multiple ethnic populations. Of...
Objective To evaluate the performance of a deep learning system (DLS) in classifying severity papilledema associated with increased intracranial pressure on standard retinal fundus photographs. Methods A DLS was trained to automatically classify 965 patients (2,103 mydriatic photographs), representing multiethnic cohort confirmed elevated pressure. Training performed 1,052 photographs mild/moderate (MP) and 1,051 severe (SP) classified by panel experts. The that 3 independent...
<i>Purpose:</i> To evaluate the long-term safety and efficacy of intravitreal ranibizumab in treatment myopic choroidal neovascularization (CNV). <i>Methods: </i>Three-year retrospective, nonrandomized, interventional case series. Forty eyes 39 patients with CNV were included; 15 previous photodynamic therapy, 25 naïve eyes. Best-corrected visual acuity (BCVA) changes, central foveal thickness (CFT), number treatments assessed, from baseline to month 36....
Abstract Purpose This paper presents a modification of the needle-assisted retropupillary fixation technique for iris-claw intraocular lenses (IOLs). We introduce novel, minimally invasive reenclavation managing subluxated IOLs. Methods The was successfully performed on four patients diagnosed with approach involved that utilized three needles: one long, straight translimbal needle crossing anterior chamber and two needles introduced through pars plana to reposition securely reenclavate IOL....
<i>Introduction:</i> The presence of large-sized drusen (≧125 µm), soft indistinct drusen, pigmentary changes, a large area and choroidal neovascular membrane in one eye have been found to be predictive risk factors late exudative age-related macular degeneration (AMD). Multimodal imaging potentially increases the possibility indentifying further potential developing wet AMD. <i>Purpose:</i> To identify morphological and/or functional baseline for development...
To identify morphological and/or functional early markers of choroidal neovascularization (CNV) development in fellow eyes patients with exudative age-related macular degeneration (AMD).This is a single-center, prospective, observational, longitudinal 2-year study.Patients were enrolled the diagnosis neovascular AMD 1 eye and maculopathy (ARM) eye. Intervention or Methods: All completed baseline assessment followed up for to 24 months repeated ophthalmic imaging assessments performed at...
The influence of normal aging in early, intermediate and high-level visual processing is still poorly understood. We have addressed this important issue a large cohort 653 subjects divided into five distinct age groups, [20;30[, [30;40[, [40;50[, [50;60[and [60;[. applied broad range psychophysical tests, testing levels the hierarchy, from local to global integration, using simple gratings (spatial contrast sensitivity -CS- high temporal/low spatial frequency or static gratings), color CS...
In multiple sclerosis (MS), even in the absence of a clinical episode optic neuritis (ON), nerve and retinal fiber layer (RNFL) may be damaged leading to dyschromatopsia. Subclinical dyschromatopsia has been described MS associated with lower motor cognitive performances.To set prevalence eyes patients without history ON, compare its ON history, explore association between disease duration, average peripapillary RNFL thickness, macular volume, performances.An observational cross-sectional...
<b><i>Purpose:</i></b> To evaluate the 36-month efficacy of intravitreal ranibizumab injections for choroidal neovascularization secondary to age-related macular degeneration (AMD) in real world clinical practice. <b><i>Methods:</i></b> Retrospective study involving 84 eyes 77 patients; 52 completed 3 years follow-up. Subjects were observed initially on a monthly basis and with extended follow-up intervals if signs quiescence detected,...
To report the case of an anterior chamber epithelial cyst after uncomplicated deep lamellar keratoplasty (DALK) treated with a tissue-sparing surgical technique.A 35-year-old female patient underwent DALK in her OS because stage IV keratoconus. The surgery was uneventful, and 3 months postoperatively, best-corrected visual acuity (BCVA) 20/25. By sixth postoperative month, cystic iris lesion noticed. grew progressively larger, BCVA dropped to 20/63 OS. Cyst excision performed.No...
Chronic relapsing inflammatory optic neuropathy (CRION) is a type of idiopathic recurrent neuritis that responds to systemic corticosteroids and relapses on steroid withdrawal or dose reduction. Central serous chorioretinopathy (CSCR) often associated with glucocorticoid therapy. This paper aims highlight CSCR as cause visual loss in patients being treated for neuritis.We describe the case 42-year-old woman history CRION her left eye who presented painful vision right diffuse disc edema....
Severe B 12 vitamin deficiency due to diminished dietary intake is a known cause of severe pancytopenia with bleeding diathesis. The authors report case sudden-onset bilateral vision loss, and multiple organ failure secondary in patient strict vegetarian diet. On funduscopic examination the had exuberant haemorrhages all retinal layers. Five months after presentation, he complete visual recovery without ophthalmological intervention.
OBJECTIVE: To compare the retinal nerve fiber layer thickness (RNFL) between patients with idiopathic Parkinson disease (iPD), LRRK2-associated Disease (LRRK2-PD) and controls, using optical coherence tomography (OCT) a novel protocol for macular evaluation. BACKGROUND: Mutations in LRRK2 gene are responsible 10[percnt] of familial autosomal dominant (PD), phenotype indistinguishable from iPD. Vision is one affected non-motor systems PD, probably due to dopaminergic deficit retina. RNFL...
Dias, Margarida Queirós MD; Raimundo, Miguel Fonseca, Pedro MDEditor(s): Winges, Kimberly M. Gilhooley, Michael J. MA, MB, BChir, DPhil Author Information
To estimate the number of ocular syphilis (OS) cases diagnosed in a tertiary care centre Portugal, correlate with increasing diagnoses and characterize OS population.
Leber's Hereditary Optic Neuropathy (LHON) has been mainly (90-95 %) associated to one of three variants: m.3460G>A, m.11778G>A, m.14484T>C. Herein, a screening method was developed for its detection, supporting clinical/therapeutics decision. It relies on real-time PCR with High-Resolution Melting (HRM) analysis. Variant classification is made using HRM Software and quality controls. A total 101 samples were analyzed. All correctly assigned: 58 wild-type, 35 positive 6 m.14484T>C, 2...