A5100669555- Traditional Chinese Medicine Studies
- Traditional Chinese Medicine Analysis
- Cardiac Imaging and Diagnostics
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Ginseng Biological Effects and Applications
- Gut microbiota and health
- Acupuncture Treatment Research Studies
- Osteoarthritis Treatment and Mechanisms
- Advanced Nanomaterials in Catalysis
- Viral Infections and Immunology Research
- MicroRNA in disease regulation
- Bone Metabolism and Diseases
- Herpesvirus Infections and Treatments
- Macrophage Migration Inhibitory Factor
- Graphene and Nanomaterials Applications
- Lipid metabolism and disorders
- Cardiac Fibrosis and Remodeling
- GDF15 and Related Biomarkers
- Healthcare and Venom Research
- Diet and metabolism studies
- Coronary Interventions and Diagnostics
- Nonmelanoma Skin Cancer Studies
- Family Caregiving in Mental Illness
- Phytochemistry and Biological Activities
Guangxi Medical University
2024-2025
First Affiliated Hospital of GuangXi Medical University
2024
Guang’anmen Hospital
2017-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2023
Fourth People's Hospital of Sichuan Province
2023
The Fourth People's Hospital
2023
China Academy of Chinese Medical Sciences
2020-2023
Sun Yat-sen University
2022
Sun Yat-sen University Cancer Center
2022
Beijing University of Chinese Medicine
2017-2021
The activation of pro-inflammatory M1-type macrophages by overexpression reactive oxygen species (ROS) and nitrogen (RONS) in synovial membranes contributes to osteoarthritis (OA) progression cartilage matrix degradation. Here, combing Pt Se with potent catalytic activities, we developed a hybrid Pt–Se nanozymes as ROS RONS scavengers exert synergistic effects for OA therapy. As result, exhibited efficient scavenging effect on levels, leading repolarization macrophages. Furthermore, the...
Abstract Background The association between trauma and melanoma has been a controversial issue. Objectives To analyse the profiles of melanoma, to determine whether is associated with development acral in Chinese population. Patients Methods Retrospective analysis 685 cases cutaneous dermatology departments Xijing Hospital northwestern China Xinan southwestern from 1982 2011. Results Of patients included study, 437 (63.8%) suffered on extremities. A total 104 (15.2%) exhibited an melanoma....
Qi stagnation and blood stasis syndrome (QS&BSS) is one of the common Zhengs in traditional Chinese medicine (TCM), which manifests as various symptoms signs, such distending pain or a tingling sensation fixed position. In recent years, number clinical trials have focused on effectiveness safety XFZYC patients with QS&BSS subtype disease, coronary heart hyperlipidaemia, ischaemic cerebrovascular gastritis, dysmenorrhoea, arthritis, terms outcomes relevant diseases. However, there lack...
Background: According to the theory of traditional Chinese medicine, phlegm and blood stasis (PBS) is pathological basis for coronary heart disease (CHD). This study aimed explore biological PBS syndrome in CHD. Methods: Using a strategy that integrated RNA-seq, DIA-based proteomics, untargeted metabolomics on 90 clinic samples, we constructed “gene–protein–metabolite” network CHD-PBS syndrome. We expanded sample size validated differential genes metabolites through enzyme-linked...
Abstract In the context of severe burn injuries, presence excessive reactive oxygen species (ROS), prolonged microbial infection, and compromised angiogenesis can contribute to metabolic reprogramming macrophages, resulting in a dysregulated inflammatory response that hinders healing process. this study, cerium oxide nanoparticles (CeNPs) are encapsulated within silk fibroin‐poly(e‐caprolactone) polymer create an electrospun PSF/CeNPs nanofiber membrane (PSF/membrane). This is further...
Abstract Introduction: Stable angina pectoris has a high prevalence and causes serious harm. Revascularization therapy can relieve to some extent, but it is not widely accepted in China due the cost secondary events. The Chinese proprietary medicine Danlou tablet been used treat pectoris, previous trials had inadequate methodologies. In this study, we aim conduct randomized controlled trial evaluate its efficacy safety on stable angina. Methods analysis: This study WeChat-based randomized,...
Qi stagnation and blood stasis syndrome (QSBSS) is a common Zheng in Traditional Chinese Medicine (TCM), describes the condition of unsmooth flow blood, which manifests as distending pain fixed body part emotional disorders, including irritability depression. However, underlying molecular mechanisms remain largely elusive. RNAs are connection between DNA proteins, reflect interaction genotypes phenotype. Of note, non-coding (nc)RNA type RNA that not translated into any protein, but has...
Unstable angina pectoris is an acute exacerbation secondary to coronary artery occlusion. In routine clinical treatment, patients with unstable are prone recurrence or aggravation of symptoms. Based on the traditional Chinese medicine (TCM) theory, phlegm, and blood stasis one main pathological factors pectoris. The treatment phlegm-blood syndrome by Gualou Danshen granules (GLDS) has been focus many trials. However, there no evidence prove safety efficacy GLDS.
Abstract Objective: Post-myocardial infarction heart failure (post-MI HF) is a prevalent cardiovascular disease. The study aims to preliminarily explore the current research status and development trends in field of post-MI HF, providing reference ideas methods for clinical scientific research. Methods: Publications related HF from 2012-2022 Web Science Core Collection's SCI-expanded dataset were extracted. Bibliometric analysis was executed using VOSviewer R-bibliometrix, encompassing...
Introduction As the early stage of coronary heart disease (CHD), borderline lesion (BCL) is defined as a 30%–70% diameter stenosis. Previous studies have demonstrated that BCL may progress to acute syndrome easily. However, routine medications available for treatments some limitations. Xuanbi antong granule (XAG) has been used treatment in China many years. shown XAG effectiveness improving clinical symptoms and quality life patients with CHD. This study aims evaluate safety BCL. Methods...
This aim of this study is to screen the differential molecules kidney deficiency and blood stasis (KDBS) syndrome in coronary heart disease by high-throughput sequencing. In addition, aims verify alterations expression levels miR-4685-3p its regulated downstream, namely, C1QC, C4, C5, using quantitative polymerase chain reaction (qPCR) enzyme-linked immunosorbent assay (ELISA), determine whether complement coagulation cascade pathway specific pathogenic pathway.Patients diagnosed with...
Background. Coronary artery stenosis is the major pathological change of coronary heart disease (CHD). Within framework traditional Chinese medicine (TCM) theory, some kinds TCM Zheng could exist in patients with CHD; accordingly, practitioners provide appropriate therapy. However, little known about association between and types stenosis. Such knowledge help improve accuracy effectiveness efforts to combine CHD treatment Therefore, aim this study determine Methods Design. This a...
Objectives . To identify the sensitive biomarker to predict effectiveness of Xue-Fu-Zhu-Yu capsules (XFZYC). Methods This nested case-control study included 5 patients with response XFZYC in treatment group, no also and control group treated placebo who participated previous RCT. The mRNAs, miRNAs, lncRNAs, circRNAs were sequenced by next-generation sequencing differential-expressed (DE) RNAs identified if <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...