A5043754120- Lung Cancer Treatments and Mutations
- Thermochemical Biomass Conversion Processes
- Chemical Looping and Thermochemical Processes
- Lung Cancer Research Studies
- Gastric Cancer Management and Outcomes
- Catalysts for Methane Reforming
- Carbon Dioxide Capture Technologies
- Thermal and Kinetic Analysis
- Colorectal Cancer Treatments and Studies
- Peptidase Inhibition and Analysis
- Protease and Inhibitor Mechanisms
- Advanced Photocatalysis Techniques
- Cell Adhesion Molecules Research
- Skin and Cellular Biology Research
- Electrocatalysts for Energy Conversion
- HER2/EGFR in Cancer Research
- Biochemical and Molecular Research
- Hybrid Renewable Energy Systems
- Chronic Myeloid Leukemia Treatments
- Industrial Gas Emission Control
- Catalytic Processes in Materials Science
- Pluripotent Stem Cells Research
- Microtubule and mitosis dynamics
- Adsorption and Cooling Systems
- Mining and Gasification Technologies
Dalian University of Technology
2020-2025
Northwestern Polytechnical University
2023
Shanxi University
2023
Shaanxi University of Science and Technology
2023
Jinzhou Medical University
2020
University of Hong Kong
2017-2018
Betta Pharmaceuticals (China)
2014-2016
Zhejiang Yongning Pharma (China)
2011-2015
Peking Union Medical College Hospital
2009
Chinese Academy of Medical Sciences & Peking Union Medical College
2009
In this work, a series of Ce-doped, Zr-doped and Zr-Ce co-doped CaO-based sorbents were prepared by the sol-gel method. The multi-cycle CO2 sorption performance test under mild conditions showed that had better stability than Ce-doped sorbents. This is because CaZrO3 higher Tammann temperature CeO2, which could inhibit growth agglomeration sorbent particles more effectively. However, compared with sorbents, rate at cycle 1. CeO2 has abundant oxygen vacancies to facilitate mobility O2−, thus...
Fast pyrolysis is commonly used in industrial reactors to convert waste tires into fine chemicals and fuels. However, current thermogravimetric analyzers are facing limitations that prevent the acquisition of kinetic information. To better understand reaction kinetics, we designed a novel thermo-balance device was capable in-situ weight measurement during rapid heating. The results showed rate substantially increased, with significant reductions time apparent activation energy compared slow...
Liquid organic hydrogen carriers (LOHCs), such as methanol and formic acid, offer a reliable solution for the challenges associated with transporting storing gaseous hydrogen. However, current industrial LOHCs are costly in limited supply due to complex synthesis methods involving gasification Fischer-Tropsch synthesis. An alternative approach utilizing efficient pyrolysis can convert biomass into substances that mimic LOHCs, making them promising avenue storage. Compounds high content,...
Abl family nonreceptor tyrosine kinases regulate cellular morphogenesis and motility through functional interactions with the actin cytoskeleton. Although are known to contain filamentous (F)-actin-binding domains at their C termini, it is unclear how structure and/or function of We show here that Abl-related kinase Arg binds positive cooperativity F-actin in vitro binding saturating a ratio one Arg/two molecules. Measurements F-actin-binding properties deletion mutants led identification...
Microtubules (MTs) help establish and maintain cell polarity by promoting actin-dependent membrane protrusion at the leading edge of cell, but molecular mechanisms that mediate cross-talk between actin MTs during this process are unclear. We demonstrate Abl-related gene (Arg) nonreceptor tyrosine kinase is required for dynamic lamellipodial protrusions after adhesion to fibronectin. arg−/− fibroblasts exhibit reduced dynamics as compared with wild-type fibroblasts, defect can be rescued...
Proteases have been implicated in the extracellular modulation required for tumor growth and invasion. In an effort to categorize those proteases contributing ovarian carcinoma progression, we utilized redundant primers conserved amino acid (AA) domains surrounding catalytic triad of His, Asp Ser amplify serine that are differentially expressed carcinomas. Using this method, identified cloned a protease named TADG-15 (tumor-associated gene 15) is overexpressed tumors. transmembrane...
The growing global energy demand and environmental challenges have underscored the urgency of developing clean sustainable sources, with hydrogen emerging as a promising alternative due to its high mass based carbon-neutral combustion properties. However, conventional production technologies, such steam reforming, are constrained by requirements, limited yields, substantial CO2 emissions. This study presents novel approach addressing these synthesizing cost-effective catalyst-sorbent hybrid...
Various liver diseases caused by damage seriously affect people's health. The purpose of this study was to clarify the effects and mechanisms carnitine palmitoyltransferase 1 (Cpt1a) on oxidative stress inflammation in injury. It found that expression Cpt1a mRNA upregulated a model injury mice. Thus, overexpression increased reactive oxygen species (ROS) production malondialdehyde (MDA) levels reduced superoxide dismutase (SOD), glutathione (GSH), peroxidase (GSH-px) an vitro also shown...
Sodium zirconate (Na2ZrO3) can capture CO2 at high temperature with efficiency. In this study, Na2ZrO3 sorbents were synthesized by wet-mixing and sol-gel methods. Both heated-drying freeze-drying applied for drying the solutions to form different porous structures in prepared samples. The material characterization cyclic sorption test carried out, effects of synthesis methods on properties studied. experimental results showed that mixing possessed a more structure smaller crystals, which...
Matrix metalloproteases are known to play an important role in tumor invasion by mediating degradation of extracellular matrix. In this study, we have investigated the expression matrix metalloprotease pump-1 gene (also referred as MMP-7, Matrilysin) 44 ovarian tumors (12 low malignant potential tumors, 32 carcinomas) and 10 normal ovaries using quantitative PCR. The PCR product was labelled with 32P a phosphoimager used determine relative compared internal control beta-tubulin. mRNA levels...
We retrospectively reviewed a total of 257 stage I to IIIa lung adenocarcinoma after resection, tested them for the epidermal growth factor receptor (EGFR) mutation, and analyzed effect perioperative treatment on survival. The results showed that in patients with an EGFR adjuvant EGFR-tyrosine kinase inhibitor monotherapy complete resection significantly prolongs disease-free survival compared chemotherapy and/or radiotherapy.Adjuvant cisplatin-based improves non-small-cell cancer (NSCLC)...
Recent studies using defined transcription factors to convert skin fibroblasts into chondrocytes have raised the question of whether osteo-chondroprogenitors expressing SOX9 and RUNX2 could also be generated during course reprogramming process. Here, we demonstrated that doxycycline-inducible expression (KLF4 [K] c-MYC [M]) for 6 days were sufficient murine SOX9+/RUNX2+ cellular aggregates together with (S) promoted conversion efficiency when cultured in a stem cell medium, mTeSR....
Background Icotinib is a small molecule targeting epidermal growth factor receptor tyrosine kinase, which shows non-inferior efficacy and better safety comparing to gefitinib in previous phase III trial. The present study was designed further evaluate the of icotinib patients with advanced non-small-cell lung cancer (NSCLC) previously treated platinum-based chemotherapy. Methods Patients NSCLC progressing after one or two lines chemotherapy were enrolled receive oral (125mg tablet, three...