A5102976267- Sport and Mega-Event Impacts
- Atherosclerosis and Cardiovascular Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Diverse Aspects of Tourism Research
- Acute Ischemic Stroke Management
- Nuclear Receptors and Signaling
- Seaweed-derived Bioactive Compounds
- China's Global Influence and Migration
- Nerve injury and regeneration
- Diverse Approaches in Healthcare and Education Studies
- Retinoids in leukemia and cellular processes
- E-commerce and Technology Innovations
- Advanced Biosensing Techniques and Applications
- 2D Materials and Applications
- Electron Spin Resonance Studies
- Diabetes Treatment and Management
- Polysaccharides and Plant Cell Walls
- Pharmacological Receptor Mechanisms and Effects
- Erythrocyte Function and Pathophysiology
- Advanced Sensor and Energy Harvesting Materials
- Heme Oxygenase-1 and Carbon Monoxide
- Stroke Rehabilitation and Recovery
- Cancer Mechanisms and Therapy
- Sulfur Compounds in Biology
Nanjing University of Chinese Medicine
2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2025
Wenzhou Medical University
2025
Wuhan University
2022-2024
Renmin Hospital of Wuhan University
2022-2024
Kyrgyz National University
2023-2024
City University of Hong Kong
2023
Luoyang Normal University
2023
Tang Du Hospital
2012-2021
Air Force Medical University
2012-2021
17-β-Estradiol (E2) is a steroid hormone involved in neuroprotection against excitotoxicity and other forms of brain injury. Through genomic nongenomic mechanisms, E2 modulates neuronal excitability signal transmission by regulating NMDA non-NMDA receptors. However, the mechanisms identity receptors remain unclear, even though studies have suggested that estrogen G-protein-coupled receptor 30 (GPR30) linked to protection ischemic In culture cortical neurons, treatment with GPR30 agonist G1...
2D heterostructures are emerging as alternatives to conventional semiconductors, such silicon, germanium, and gallium nitride, for next-generation electronics optoelectronics. However, the direct growth of heterostructures, especially those with metastable phases still remains challenging. To obtain transition metal dichalcogenides (TMDs) designed phases, it is highly desired develop phase-controlled synthetic strategies. Here, a facile chemical vapor deposition method reported prepare...
Background The tyrosine receptor kinase inhibitor (TRKi) entrectinib is used to treat neurotrophic (NTRK) fusion-positive solid tumors and ROS1-positive patients. Despite its impressive efficacy against cancer, the clinical application still limited by central nervous system (CNS)-related toxicities. However, precise mechanism of such CNS-related toxicities remains elusive. Methods effect entrectinib-induced nerve cell damage was evaluated cells (PC12, HT22 SK-N-SH) based in vitro models....
Background: Recent studies have revealed that a novel selective sodium-glucose cotransporter 1 (SGLT1) inhibiton has shown beneficial effects in cardiovascular diseases. However, the question of whether SGLT1 inhibition influences diabetic cardiomyopathy (DCM) remains unanswered. In this study, we investigated influence and underlying mechanism SGLTI on DCM. Methods: levels were measured patients with similar conditions who visited our hospital from January to December 2019. Wistar male rats...
Song H, Zhao Qu Y, Sun Q, Zhang F, Du Z, Liang W, Qi Yang P. Carbon monoxide releasing molecule-3 inhibits concurrent tumor necrosis factor-α- and interleukin-1β-induced expression of adhesion molecules on human gingival fibroblasts. J Periodont Res 2011; 46: 48–57. © 2010 John Wiley & Sons A/S Background Objective: (CORM-3) is a newly reported compound that has shown anti-inflammatory effects in number cells. In this study, we aimed to investigate the influence CORM-3 factor-α (TNF-α)-...
<p>The cytokine interleukin-6 (IL-6) mediates a wide range of inflammatory and immune responses. Tumor Necrosis Factor α (TNF-α) has myriad pro-inflammatory effects on the skin. In this study, we investigated localizations expression levels IL-6, TNF-α NF-κB in skin <em>Rana dybowskii</em> during breeding period pre-hibernation. Histologically, dybowskii </em>consists epidermis dermis. Four kinds cells were identified pre-hibernation, while dermis was composed...
ABSTRACT Background Early on in the development of diabetes, skeletal muscles can exhibit microarchitectural changes that be detected using texture analysis (TA) based volume transfer constant ( K trans ) maps. Nevertheless, there have been few studies and thus we evaluated microvascular permeability TA bone marrow diabetics with critical limb ischemia (CLI). Methods Eighteen male rabbits were randomly assigned equally into an operation group hindlimb a sham‐operated diabetes only, control...
Background: The modern world is experiencing an unflagging interest in rural tourism, causing its consideration as a powerful tool of international economic strategies for the development local communities, preserving national traditions and ensuring sustainable growth regions. Aims: study's goal to examine features promotion trends Chinese tourism context One Belt, Road program. Materials Methods: To achieve research objectives, following methods were used: axiomatic, hypothetico-deductive,...
The aim of this study is to investigate the relation between CaMKII S-nitrosylation and its activation, as well underlying mechanism, after global cerebral ischemia-reperfusion.The rat model ischemia-reperfusion was established by four-vessel occlusion 15 min reperfusion different times. nNOS inhibitor 7-nitroindazole (7-NI), exogenous nitric oxide donor GSNO (nitrosoglutathione), or N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 were administered before ischemia. expressions...
Hepatitis C virus (HCV) infection related hepatitis remains one of the most serious health problems worldwide. During investigation hypervariable region 1 (HVR1) HCV, a seven amino acids mimic peptide (GQTYTSG, named 7-P) was identified within N-terminal HVR1 that could protect porcine serum (PS)-induced hepatic injury in rats. 7-P not only decrease levels aminotransferases (ALT, AST), alkaline phosphatase (AKP), and billirubin, but were also effective reversing histopathological evidence...
China can be considered one of the countries that have maintained longest duration epidemic prevention and control policies.The shift in policies presents both opportunities challenges for development sports tourism China.Compared to other forms tourism, has a certain threshold athletic skills may entail risks.In recent years, rapid webcasting on internet become decisive factors young people their travel choices.To promote healthy sustainable after transition policies, this study applied...
We evaluated skeletal muscle vascular permeability in diabetic rabbits with critical limb ischaemia using quantitative dynamic contrast agent-enhanced (DCE) magnetic resonance imaging (MRI) and explored the feasibility of DCE-MRI Ktrans-based texture analysis for assessing early slight ischaemia-related structural changes. Twenty-four male New Zealand white (2.7 ± 0.3 kg; n = 12 each sham-operated experimental groups) underwent axial MRI vastus lateralis at 1, 2, 3 weeks after alloxan...
Background Glycogen synthase kinase-3β (GSK-3β) plays an important role in glucose metabolism,and it may be affect the occurrence of diabetic retinopathy(DR). Objective The present study was to investigate effect valsartan and fluvastatin on expression GSK-3β retina diabetes rat model.Methods Diabetes mellitus models were induced by intrapenetoneal injection streptozotocin(STZ) 47 clean Sprague-Dawley(SD) rats then randomedly divided into 4 groups.Ten other normal served as control...