A5100413479- Atmospheric chemistry and aerosols
- Nutrition, Genetics, and Disease
- Ferroelectric and Piezoelectric Materials
- Multiferroics and related materials
- Magnetic properties of thin films
- Air Quality Monitoring and Forecasting
- Adipose Tissue and Metabolism
- Perovskite Materials and Applications
- Cardiac electrophysiology and arrhythmias
- Genetics and Neurodevelopmental Disorders
- Cancer survivorship and care
- Inflammatory Bowel Disease
- CRISPR and Genetic Engineering
- Tendon Structure and Treatment
- Atmospheric Ozone and Climate
- Electronic and Structural Properties of Oxides
- Ubiquitin and proteasome pathways
- MRI in cancer diagnosis
- Autophagy in Disease and Therapy
- Quantum Dots Synthesis And Properties
- Nuclear Receptors and Signaling
- Advanced Condensed Matter Physics
- Renal and Vascular Pathologies
- Tuberous Sclerosis Complex Research
- Case Reports on Hematomas
Hubei University of Medicine
2022-2024
Ministry of Agriculture and Rural Affairs
2022
Northeast Agricultural University
2022
Shandong First Medical University
2022
Fujian Provincial Hospital
2020-2022
Kunming Medical University
2022
Institute of Physics
2020-2022
Xinjiang Medical University
2021-2022
Wuhan Sports University
2022
Huainan Union University
2022
Abstract Emerging evidence suggests that USP39 plays an important role in the development of hepatocellular carcinoma (HCC). However, molecular mechanism by which promotes HCC progression has not been well defined, especially regarding its putative ubiquitination function. Zinc-finger E-box-binding homeobox 1 (ZEB1) is a crucial inducer epithelial-to-mesenchymal transition (EMT) to promote tumor proliferation and metastasis, but regulatory ZEB1 stability remains enigmatic. Here, we reveal...
Abstract Perovskite (PVSK) photovoltaics have been a promising field in the exploitation of renewable energy due to fascinating performances PVSK materials and devices. Although efficiency is gradually approaching that traditional solar cells, stability still challenge. Hence, tomato lycopene, botanic antioxidant, introduced as modification layer on absorber prevent moisture oxygen erosion, for enhanced both intrinsic environmental stabilities. This inserted protection can also interact with...
The ability to controllably manipulate complex topological polar configurations such as flux-closures via external stimuli may allow the construction of new electromechanical and nanoelectronic devices. Here, using atomically resolved in situ scanning transmission electron microscopy, we find that PbTiO3/SrTiO3 superlattice films are mobile can be reversibly switched ordinary single ferroelectric c or a domains under an applied electric field stress. Specifically, initially drives movement...
Our purpose was to compare toxicity and biochemical control in postprostatectomy patients treated with conventional (66 Gy) or dose-intensified (72 radiation therapy.Patients who had stage pT3-4, positive surgical margins, rising prostate-specific antigen ≥ 0.2 ng/mL after radical prostatectomy were randomly assigned receive either 66 Gy 33 fractions 72 36 fractions. A primary endpoint assess the difference progression-free survival (bPFS) between these 2 cohorts, secondary endpoints...
Previous studies proved that heavy metals could increase the risk of disease by acting on gut microbiota. Meanwhile, microbiota played important roles in detoxifying metals. However, response to and which microbes dominated this detoxification processes are still unclear. This study investigated difference high-fat-diet (HFD) normal-diet (ND) their effects arsenic (As), cadmium (Cd), lead (Pb) exposure. Results showed ND HFD was significantly different responded As, Pb, Cd exposure...
Background and aims Disposable enema kits are commonly used for bowel preparation, with the anal tube typically positioned near rectal ampulla. This study assesses feasibility safety of deeply inserting an in cases acute malignant left-hemicolon obstruction. Methods A retrospective analysis was conducted on 42 patients who underwent emergency endoscopic decompression via a inserted obstruction from January 2021 to September 2024 at single center, Endoscopy Centre Affiliated Hospital Putian...
To evaluate the efficacy and safety of SHR4640, a highly selective urate transporter 1 inhibitor, in Chinese subjects with hyperuricaemia.This was randomized double-blind dose-ranging phase II study. Subjects whose serum uric acid (sUA) levels were ≥480 µmol/l gout, without gout but comorbidities, or ≥540 enrolled. randomly assigned (1:1:1:1:1) to receive once daily 2.5 mg, 5 10 mg 50 benzbromarone placebo, respectively. The primary end point proportion who achieved target sUA level ≤360 at...
To verify the ability of infrared thermography in objectively identifying pressure injury and its application value early warning injury. There is subjectivity assessing risk as well diagnosis clinical settings, which makes detection prevention difficult. Prospective, cohort study. Four hundred fifteen patients admitted to adult intensive care units were enrolled by a convenience sampling method, they received follow-up monitoring for 10 days. The was assessed via Braden scale, thermal...
Abstract Ubiquitin‐specific protease 39 (USP39) is frequently overexpressed in a variety of cancers, and involved the regulation various biological processes, such as cell proliferation, cycle progression, apoptosis pre‐messenger RNA splicing. Nevertheless, roles mechanisms USP39 colon cancer remain largely unknown. In this study, we analyzed whether can be molecular target for treatment cancer. Whilst overexpression was detected human tissues lines, knockdown observed to inhibit growth...
Mechanical stimulation and platelet-rich plasma (PRP) have been shown to be beneficial for healing of the bone-tendon interface (BTI), but few studies explored efficacy a combination these applications. We investigated effect mechanical combined with PRP on rotator cuff repair in mice.Mechanical can enhance BTI murine model repair.Controlled laboratory study.A total 160 C57BL/6 mice were used. Overall, 40 used prepare PRP, while 120 underwent acute supraspinatus tendon (SST) repair. The...
Drug abuse has many negative effects not only on individuals but also society. Nowadays, researchers pay a lot of attention to quality life drug addicts. However, there are few scales available measure The scale QLICD-DA (quality instrument for chronic diseases-drug addition) developed by modular approach could be used addicts with good validity, reliability and sensitivity.This study is aimed understand the status influencing factors in suitable sensitively scale, hypothesis being different...
Fusarium wilt is one of the most destructive and less controllable diseases in melon, which usually caused by fusarium oxysporum . In this study, transcriptome sequencing Yeast Two-Hybrid (Y2H) methods were used for quantification differentially expressed genes (DEGs) involved (f. sp. melonis race 1) stress-induced mechanisms contrasted melon varieties (M4-45 “susceptible” MR-1 “resistant”). The interaction factors Fom-2 resistance also explored response to plant-pathogen infection...
Diabetes can increase the risk of coronary heart disease, and also mortality rate disease in diabetic patients. Although reperfusion therapy preserve viable myocardium, fatal injury occur. Studies have shown that diabetes aggravate myocardial ischemia-reperfusion injury, ERK1/2 reduce but its mechanism hyperglycemic is unclear. This study sought to explore extracellular signal-regulated kinase 1/2 (ERK1/2) ischemia (I/R) injury.H9C2 cardiomyocytes were treated with high-glucose (HG) medium...
Introduction Jacaranda mimosifolia , native to South America, is a notable ornamental tree widely used in Chinese urban landscaping due its aesthetic and environmental value. Despite popularity, the cultivation of J. China faces challenges, including intermittent failures various regions. This study assesses potential distribution response climate change, providing insights for application promotion. Methods Using MaxEnt software, we developed an ecological niche model from 218 records...
NOX (NOX = NO + NO2) emissions measurements in Beijing are of great significance because they can aid understanding how pollution develops mega-cities throughout China. However, difficult to measure due changes wind patterns and moving sources on roads during measurement. To obtain good spatial coverage different ring over a short amount time, two mobile differential optical absorption spectroscopy (DOAS) instruments were used emission flux from April 18th 26th, 2018. In addition, profile...
Genetic variation of macrophage migration inhibitory factor (MIF) gene has been linked to coronary artery disease. We investigated an association between the polymorphism MIF rs2070766 and acute syndromes (ACS) predictive value in clinical outcomes. This study involved 963 ACS patients 932 control subjects from a Chinese population. All participants were genotyped for single nucleotide (SNP) using SNPscan™. A nomogram model genetic variables was established predict risk ACS. Major adverse...
Water vapor transport affects regional precipitation and climate change. The measurement of precipitable water (PW) flux (WVF) is great importance for the study transport. This presented a new method computing PW estimating WVF using vertical column density (VCD) profile retrieved from multi-axis differential optical absorption spectroscopy (MAX-DOAS), combined with European Centre Medium-Range Weather Forecasts (ECMWF) ERA5 wind profiles. We applied our to MAX-DOAS observations in coastal...
The broken symmetry at structural defects such as grain boundaries (GBs) discontinues chemical bonds, leading to the emergence of new properties that are absent in bulk owing couplings between lattice and other parameters. Here, we create a two-dimensional antiferrodistortive (AFD) strontium titanate (${\mathrm{SrTiO}}_{3}$) phase $\mathrm{\ensuremath{\Sigma}}13(510)/[001]$ ${\mathrm{SrTiO}}_{3}$ tilt GB room temperature. We find an anomalous room-temperature AFD with thickness approximate...