- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Pharmacology and Obesity Treatment
- Cardiovascular Disease and Adiposity
- Nutritional Studies and Diet
- Consumer Attitudes and Food Labeling
- Venous Thromboembolism Diagnosis and Management
- Obesity, Physical Activity, Diet
- Anesthesia and Pain Management
- Central Venous Catheters and Hemodialysis
- Health and Lifestyle Studies
- Parasitic Infections and Diagnostics
- Parkinson's Disease Mechanisms and Treatments
- Physical Activity and Health
- Parasite Biology and Host Interactions
- Coccidia and coccidiosis research
- Cardiac, Anesthesia and Surgical Outcomes
- Nutrition and Health in Aging
- Vascular Anomalies and Treatments
- Rural and Ethnic Education
- Neuropeptides and Animal Physiology
- Eating Disorders and Behaviors
- Diagnosis and Treatment of Venous Diseases
- Transcranial Magnetic Stimulation Studies
- Neurological disorders and treatments
Universidade Estadual de Londrina
2024
Beneficência Portuguesa de São Paulo
2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2022-2023
Universidade de São Paulo
2018-2022
Universidade Estadual de Campinas (UNICAMP)
2020
Universidade do Porto
2019
Hospital do Coração
2014-2018
Juliana Kinderziekenhuis
2018
Hospital of St. Francis Xavier
2017
Faculdade de Medicina de São José do Rio Preto
2003
Background: Recent research efforts on bariatric surgery have focused metabolic and diabetes mellitus resolution. Randomized trials designed to assess the impact of in patients with obesity hypertension are needed. Methods: In this randomized, single-center, nonblinded trial, we included (using ≥2 medications at maximum doses or >2 moderate doses) a body mass index between 30.0 39.9 kg/m 2 . Patients were randomized Roux-en-Y gastric bypass plus medical therapy alone. The primary end...
Background: Midterm effects of bariatric surgery on patients with obesity and hypertension remain uncertain. Objective: To determine the 3-year Roux-en-Y gastric bypass (RYGB) blood pressure (BP) compared medical therapy (MT) alone. Design: Randomized clinical trial. (ClinicalTrials.gov: NCT01784848) Setting: Investigator-initiated study at Heart Hospital (HCor), São Paulo, Brazil. Participants: Patients receiving least 2 medications maximum doses or more than moderate a body mass index...
Bariatric surgery is an effective strategy for blood pressure (BP) reduction, but most of the evidence relies on office BP measurements. In this study, we evaluated impact bariatric 24-hour profile, variability, and resistant hypertension prevalence. This a randomized trial including obese patients with grade 1 2 using at least antihypertensive drugs maximal doses or >2 moderate doses. Patients were allocated to either Roux-en-Y Gastric Bypass (RYGB) combined medical therapy alone 12 months....
Appropriate dietary recommendations represent a key part of secondary prevention in cardiovascular disease (CVD). We evaluated the effectiveness implementation nutritional program on quality diet, events, and death patients with established CVD.In this open-label, multicenter trial conducted 35 sites Brazil, we randomly assigned (1:1) aged 45 years or older to receive either BALANCE Program (experimental group) conventional nutrition advice (control group). The included unique education...
Obesity and overweight are becoming progressively more prevalent worldwide independently associated with a significant increase in the risk of cardiovascular diseases. Systemic arterial hypertension is frequently found association obesity contributes significantly to increased risk. We hypothesise that Roux-en-Y gastric bypass (RYGB) surgery, procedure effectively reduces body weight, can also positively impact blood pressure control obese hypertensive individuals.A unicentric, randomised,...
Abstract BACKGROUND Human morbid obesity is increasing worldwide in an alarming way. The hypothalamus known to mediate its mechanisms. Deep brain stimulation (DBS) of the ventromedial (VMH) may be alternative treat patients refractory standard medical and surgical therapies. OBJECTIVE To assess safety, identify possible side effects, optimize parameters continuous VMH-DBS. Additionally, this study aims determine if VMH-DBS will lead weight loss by causing changes body composition, basal...
We have previously developed ammonium sulphate gradient loaded liposomes to encapsulate dibucaine. Thus, the purpose of this study was evaluate pre-clinical safety and effectiveness novel ionic liposomal formulation dibucaine (DBC), as described in previous work. Effectiveness evaluated vivo on Wistar rats (n = 8) that received plain DBC or (DBCLUV). Control empty (without DBC) saline were also used control. Sciatic nerve block performed using formulations controls (0.4 mL). A hindpaw...
Roads and highways are of paramount importance for national trade transportation. Linked to this, we observe various environmental impacts, including the invasion wildlife habitat, roadkill wild animals, consequent harm fauna in vicinity highways. The aim study was characterize intestinal parasitic animals killed by Northern Paraná. Wild were collected situ on main northern region Paraná sent State University Londrina autopsy biological material collection. parasitological fecal examinations...
Nasal haemorrhage or nosebleed, is the most common of haemorrhages due to intense vasculization nose, fragility nasal mucous membrane and its vulnerability traumas irritant agents. The aim this study report on a reduction episodes nosebleed in two patients with use amnophtone. A 34-year-old male patient 44- year-old female presented histories more nosebleeds per week, despite treatment during acute phase. They both sought medical assistance for other vascular complaints, which were...
Objective: To assess whether aerobic exercise training reduces 24-hour ambulatory blood pressure (ABP) in patients with resistant hypertension (RH). Design and method: Twenty-five (age: 59.4 ± 7.4 years old, weight: 79.3 12.7 kg, body mass index: 29.4 4.1 kg/m2) were randomized to either (EG, n = 16) or control group (CG, 9). Aerobic was constituted by 3 sessions per week of 40-min walking cycling at 50–70% VO2peak, for months. Ambulatory recorded the non-dominant arm intervals 20/20 minutes...
The Cardioprotective Nutritional Program (BALANCE Program) was created for the secondary cardiovascular prevention setting, shown to be effective in improving diet quality, body weight and risk factor individuals with previous disease. However, it has been not tested among employees at primary conditions. aim of this study evaluate feasibility BALANCE a workplace, its possible effects on composition factors. This before-after conducted an Occupational Medicine Service tertiary hospital....
Leukemia is a form of blood cancer that mainly affects children and adolescents but can also affect young people adults. This disease result the accumulation cells in bone marrow which compromises manufacture red giving rise to anemia, affecting production white causing infections. When reaching platelets causes hemorrhages, this advances very quickly, needing be treated quickly for successful treatment. Thus, objective study was investigate prevalence leukemia Paraíba, from 2017 2022....
Background: Bariatric surgery represents an effective strategy for office blood pressure (BP) reduction in obese hypertensive patients. However, no previous study evaluated the impact of bariatric on 24-h BP profile, non-dipping status and incidence resistant hypertension (RH). Methods: This is a sub-analysis randomized clinical trial including patients with grade 1 2 obesity, aged 18 to 65 years, using at least drugs optimal doses or >2 moderate doses. Patients were randomly allocated...