A5076359622- COVID-19 Clinical Research Studies
- Plant-based Medicinal Research
- Cancer Treatment and Pharmacology
- Sustainable Supply Chain Management
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Enhanced Oil Recovery Techniques
- Hematological disorders and diagnostics
- Management of metastatic bone disease
- Anesthesia and Pain Management
- Natural product bioactivities and synthesis
- Phytochemical Studies and Bioactivities
- COVID-19 and Mental Health
- Petroleum Processing and Analysis
- MicroRNA in disease regulation
- Magnetic and Electromagnetic Effects
- Pain Management and Opioid Use
- Mosquito-borne diseases and control
- Wnt/β-catenin signaling in development and cancer
- Cancer therapeutics and mechanisms
- HER2/EGFR in Cancer Research
- Mining and Resource Management
- SARS-CoV-2 and COVID-19 Research
- Healthcare and Venom Research
Hunan Normal University
2024
Environment and Climate Change Canada
2024
Southwest Petroleum University
2024
Qingdao Municipal Hospital
2015-2021
Qingdao University
2015-2021
Zhangjiakou Academy of Agricultural Sciences
2020
Nanjing Medical University
2020
The coronavirus disease 2019 (COVID-19) epidemic has been almost controlled in China under a series of policies, including "early diagnosis and early treatment". This study aimed to explore the association between treatment with Qingfei Paidu decoction (QFPDD) favorable clinical outcomes. In this retrospective multicenter study, we included 782 patients (males, 56 %; median age 46) confirmed COVID-19 from 54 hospitals nine provinces China, who were divided into four groups according...
Background: Novel coronavirus pneumonia (NCP) is often changing rapidly and fatal. Early detection early triage of disease 2019 (Covid-19) the key to success management disease. An easily obtainable yet accurate variable for both diagnosis prognosis urgently needed. We aim report predictive Value Neutrophil-to-Lymphocyte Ratio(NLR) worse clinical course COVID-19, which have not been well demonstrated. Methods: Our study consisted two stages, at first stage, a retrospective, single-center,...
Human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) accounts for about 20% to 30% of all BC subtypes and is characterized by invasive disease poor prognosis. With the emergence anti-HER2 target drugs, HER2-positive patient outcomes have changed dramatically. However, treatment failure mostly due drug resistance special needs different subgroups. Small molecule tyrosine kinase inhibitors can inhibit multiple targets human family activate PI3K/AKT, MAPK, PLC γ, ERK1/2,...
The first concise synthesis of natural flavonoid glycosides, oroxins C (1) and D (2), which were isolated from the seeds Oroxylum indicum, was efficiently achieved by a convergent strategy. synthesized products 1 2 evaluated for their inhibitory activities against α-glucosidase, α-amylase, lipase. Compound showed strong α-amylase lipase inhibition, with IC 50 values 210 190 μM, respectively, but exhibited no activity α-glucosidase. inhibition α-glucosidase lipase, respective 180 80 μM.
In this work, the interaction performance of zwitterionic surfactant [dodecyl dimethyl sulfopropyl betaine (DSB-12) and hexadecyl (DSB-16)] at n-octadecane oil surface is investigated from experimental simulation insights. For a macroscopic experiment, interfacial interferometry technology was developed for real-time monitor performances to obtain quantitative thickness mass results. The Langmuir model characterized by thermodynamic analysis, deducing aggregation spontaneity DSB-16 > DSB-12...
Objective To obtain a better understanding of the prevalence and management pain in patients undergoing radiotherapy for cancer Shandong Province, China. Methods This cross-sectional study used questionnaire during face-to-face interviews to collect data from physicians regarding recognition, treatment waiting period before commencement period. Physicians were recruited 10 tertiary Class A hospitals across Results total 184 87 study. During period, was reported by according their experience...
e22066 Background: There were few effective regimens in treating advanced malignant tumor, especially for those which previous routine genetic assay had not yielded a targetable alteration. In this study, broad, hybrid capture-based next generation sequencing (NGS) was used to identify additionally alterations from cancer tissue. Consequently, approved molecular target drugs or available agents on clinical trials could be selected these driver-negative patients. Methods: 114 cases of tumor...
Background: Few studies have examined the association between treatment given time and clinical outcomes, which is indeed of great importance to management coronavirus disease 2019 (COVID-19). We performed this study explore whether early brings favorable outcomes. Methods: In retrospective multicenter study, we included patients aged 18 87 years with confirmed COVID-19 on admission from 54 hospitals in nine provinces China 21 January 10 March, 2020. Final date follow-up was March 17, All...
Abstract Background : Thoracic radiation therapy plays an important role in the treatment of inoperable lung cancer. However, radiotherapy-induced toxicity poses challenge for oncologists. Research has shown that Compound Kushen Injection (CKI) anti-inflammatory activity and can reduce when given with chemotherapy. In present trial, we investigated whether CKI also decrease chemoradiotherapy-induced thoracic cancer patients. Methods A prospective, open, randomized, multi-center study was...
Abstract Background: Increasing evidence indicates cancer-associated inflammatory biomarkers show great promise for predicting prognosis of cancer patients. The objective this study aims to evaluate the prognostic significance lymphocyte-to-monocyte ratio in patients with gallbladder carcinoma. Methods: Receiver operating characteristic curves was used determine cut-off values LMR at detecting death. primary outcome overall survival, which estimated by Kaplan-Meier method. Univariate...
Abstract Background: Thoracic radiation therapy plays an important role in the treatment of inoperable lung cancer. However, radiotherapy-induced toxicity poses challenge for oncologists. Research has shown that Compound Kushen Injection (CKI) anti-inflammatory activity and can reduce when given with chemotherapy. So, we hypothesis CKI decrease chemoradiotherapy-induced thoracic cancer patients conducted this randomized, multi-center study. Methods: A prospective, open, multi-center，phase IV...