A5071513905- Metabolomics and Mass Spectrometry Studies
- Computational Drug Discovery Methods
- Gene expression and cancer classification
- Bioinformatics and Genomic Networks
- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Orthopedic Infections and Treatments
- Nutrition, Genetics, and Disease
- Cancer, Lipids, and Metabolism
- Cancer Cells and Metastasis
- Hearing, Cochlea, Tinnitus, Genetics
- Cancer Genomics and Diagnostics
- Total Knee Arthroplasty Outcomes
- Advanced Breast Cancer Therapies
- Cancer, Hypoxia, and Metabolism
- Ear and Head Tumors
- Surgical site infection prevention
- Orthopaedic implants and arthroplasty
- Bariatric Surgery and Outcomes
- Gastric Cancer Management and Outcomes
- Sarcoma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Radiomics and Machine Learning in Medical Imaging
- Explainable Artificial Intelligence (XAI)
- Phonocardiography and Auscultation Techniques
St Vincent's Hospital
2017-2024
University of California, Los Angeles
2020-2022
Babylon Health
2020
Memorial University of Newfoundland
2017-2020
Ohio Northern University
2018
Hospital of Prato
2015-2017
Nuovo Ospedale di Prato
2016-2017
Oregon Health & Science University
2017
King Saud University
2017
University Hospital Schleswig-Holstein
2015
// Luca Malorni 1,2 , Silvano Piazza 3,4 Yari Ciani 3 Cristina Guarducci 1 Martina Bonechi Chiara Biagioni Christopher D. Hart 2 Roberto Verardo Angelo Di Leo and Ilenia Migliaccio “Sandro Pitigliani” Translational Research Unit, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy Medical Oncology Department, Laboratorio Nazionale CIB (LNCIB), Area Science Park, Functional Genomics & Bioinformatics Units, Trieste, 4 Core Facility, Centre for...
Abstract Purpose: Detecting signals of micrometastatic disease in patients with early breast cancer (EBC) could improve risk stratification and allow better tailoring adjuvant therapies. We previously showed that postoperative serum metabolomic profiles were predictive relapse a single-center cohort estrogen receptor (ER)–negative EBC patients. Here, we investigated this further using preoperative samples from ER-positive, premenopausal women who enrolled an international phase III trial....
Movement provides a link between individual behavioral ecology and the spatial temporal variation in an individual's landscape. Individual movement traits is important axis of animal personality, particularly context foraging ecology. We tested whether caribou (Rangifer tarandus) displayed plasticity space-use behavior across gradient resource aggregation. quantified first-passage time range-use ratio as proxies for movement-related examined how these varied at level gradient. Our results...
Abstract Human activities are altering the fundamental geography of biogeochemicals. Yet we lack an understanding how spatial patterns in organismal stoichiometry affect biogeochemical processes and tools to predict impacts global changes on processes. In this contribution develop stoichiometric distribution models (St DM s), which allow us map structure resource elemental composition across a landscape evaluate responses consumers. We parameterise St s for consumer‐resource (moose‐white...
Abstract: Medullary thyroid cancer is an uncommon malignancy for which until recently little effective treatment existed. It often characterized by mutation and overexpression of the receptor tyrosine kinases RET (rearranged during transfection), VEGFR2 (vascular endothelial growth factor 2) MET (mesenchymal-epithelial transition factor), make attractive targets drug development. Cabozantinib orally bioavailable kinase inhibitor blocks MET, VEGRF2 RET, has shown considerable activity in...
Abstract A global shift is occurring as hospital procedures move to ambulatory surgical settings. Surgeons have performed outpatient sleeve gastrectomy (SG) in bariatric surgery since 2010. However, prospective trials are needed ensure its safety before widespread adoption. Purpose The study aimed present a comprehensive report on the data collection of 30-day outcomes primary laparoscopic SG (LSG). This trial seeks assess whether LSG non-inferior hospital-based selected patients who meet...
Introduction The use of immune checkpoint inhibitors (ICI) targeting the PD-1/PD-L1 pathway has changed landscape in treatment triple negative breast cancer (TNBC). ICI pembrolizumab combination with chemotherapy now forms a standard care for advanced PD-L1 positive TNBC and as part neoadjuvant therapy high-risk early-stage disease. Evidence this space is rapidly advancing.
Workplace stress and burnout are recognized phenomena which impact negatively on the delivery of care by health social work organizations. In an attempt to address negative consequences in workplace, a collaborative Participatory Action Research project (PAR), involving two large organizations, namely Healthcare Trust Social Services Organization United Kingdom (England) was conducted. The involved team professionals from Anglia Polytechnic University working with senior managers employees...
A multidisciplinary approach to the management of tongue cancer is vital for achieving optimal patient outcomes. Nursing and allied health professionals play essential roles within team. We developed symposia comprising a series online lectures offering detailed perspective on role each discipline consumer has in patients with cancer. The topics, including epidemiology prevention, diagnosis, treatment planning, surgery, adjuvant care, recurrent or metastatic disease, were thoroughly...
Abstract In the context of health services, decisions regarding priorities for social work intervention and, hence, allocation expertise and resources have traditionally been based on an interaction between knowledge, principles skills, historical precedence, policy, multidisciplinary team requirements, manager opinion. current traditional practices are questioned it has become essential as a profession to clarify its role, choice interventions, state clearly strongly, basis core practice...
Abstract Background The durability of endoprostheses after limb salvage surgery is influenced by surgical factors (resection length, implant location, and residual bone quality), design (modular versus custom design, rotating fixed hinge, coating, collars, the use cross pins), host (patient’s immune status, activity levels, age). In general, radiation therapy increases risk fractures, infection, delayed wound healing, impaired osseointegration. Several studies have shown exposure to be...
6043 Background: Hearing loss with cisplatin (CP) chemotherapy is common. DB-020 a formulation of thiosulfate for intratympanic (IT) injection being developed to reduce CP ototoxicity. The primary objective this Phase 1 study was evaluate the safety and tolerability repeated IT injections DB-020. A secondary compare hearing changes vs. placebo. Methods: Subjects scheduled at least 3 cycles cumulative exposure ≥280 mg/m 2 were randomized blinded, bilateral, (12% or 25%) in one ear placebo...
We report on an 8 year old boy with primary cardiac anaplastic large cell lymphoma (ALCL), in whom the diagnosis was challenging and who treated modified chemotherapy without radiation therapy according to ALCL 99 study protocol [1]. Two years 4 months after completion of is complete remission normal function.
JDSMBias is "systematic error introduced into sampling or testing by selecting encouraging one outcome answer over others." 1 Scientific studies are likely to be subject various types of bias that could limit the generalizability results.As clinicians, we need aware potential sources and how they may relevant our specific patient populations.Recognition avoidance in scientific research has been very well described. 2,3Some familiarity with gives clinicians tools critically evaluate...