A5101622767- Ovarian cancer diagnosis and treatment
- Monoclonal and Polyclonal Antibodies Research
- Lung Cancer Treatments and Mutations
- Bladder and Urothelial Cancer Treatments
- PARP inhibition in cancer therapy
- Endometrial and Cervical Cancer Treatments
- Renal cell carcinoma treatment
- Food Quality and Safety Studies
- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pharmacological Effects of Natural Compounds
- Urological Disorders and Treatments
- Cervical Cancer and HPV Research
- Polyamine Metabolism and Applications
- Diverse Topics in Contemporary Research
- Angiogenesis and VEGF in Cancer
- Diet and metabolism studies
- Immunotherapy and Immune Responses
- Diverse Approaches in Healthcare and Education Studies
- Natural Products and Biological Research
- Morinda citrifolia extract uses
- Bacterial Genetics and Biotechnology
- HER2/EGFR in Cancer Research
- Cancer Immunotherapy and Biomarkers
Framingham State University
2025
Hannam University
2016-2024
Yonsei University
2024
Severance Hospital
2024
Seoul National University
2007-2018
Sogang University
2016
National Cancer Center
2009
Japanese encephalitis (JE) cases have been increasingly reported recently especially in Seoul and its vicinity.Pigs are known as amplifying host of JE virus (JEV), but do not play an important role these recent events because pig-breeding is common Seoul.The distribution the density migratory birds correlated with cities they might be highly potential hosts contributing to transmit JEV metropolitan areas.JE genotype sero-prevalence should determined for verification transmission route...
There is a global and increasing demand for natural ingredients that support the human immune response. In this study, immunomodulatory effect mechanism of action rice bran extract fermented by Lentinus edodes was investigated. The potential (FRB) processed (RB) evaluated using male BALB/c mice whose immunity lowered Cyclophosphamide (CY). changes in weight thymus spleen, immunoglobulins, cytokine expressions were measured as biomarkers immunomodulating after 14 days oral administration FRB...
TPS5627 Background: Recurrent gynecological clear cell carcinoma (rGCCC) is known for low objective response rates to chemotherapy. Prior preclinical and clinical data suggests potential synergy of immune checkpoint inhibitor adding bev in rGCCC. Dostarlimab, a humanized monoclonal antibody targeting PD-1, combined with the anti-angiogenic bevacizumab, presents novel therapeutic approach. The aim present study investigate efficacy dostarlimab +/- bevacizumab Methods: DOVE global,...
Consumption of alcohol injures DNA, and such damage is considered to be a primary cause for the development cancer many other diseases essentially due reactive oxygen species generated from alcohol. To sensitively detect alcohol-induced DNA lesions in biological system, we introduced novel analytical platform visualization single genomic molecules using E. coli. By fluorescently labelling lesions, our approach demonstrated, with highest sensitivity, that could count number induced by...
Citrus fruits are widely distributed in East Asia, and tea made from citrus peels has demonstrated health benefits, such as a reduction fever, inflammation, high blood pressure. However, leaves have not been evaluated extensively for their possible benefits. In this study, the α-glucosidase-inhibitory activity of Jeju hot-water (CW) ethyl alcohol (CE) extracts, along with hesperidin (HP) (a bioactive compound leaf extracts), was investigated, furthermore, effect on postprandial glucose an...
Primary endometrioid adenocarcinoma developed at urethrovaginal septum has not been reported. A 61-yr-old woman presented with recurrent urinary tract infection. She had received hormone replacement treatment estrogen and progesterone for 5 yr. pinpoint ulceration slightly elevated anterior vaginal wall was found biopsy revealed adenocarcinoma. Magnetic resonance imaging showed the 4.3 cm sized mass in septum. undergone pelvic exenteration, lymph node dissection, urostomy ileal conduit....
TPS5632 Background: Mucin 16 (MUC16) is a cell surface glycoprotein that overexpressed in ovarian cancer (OC) and endometrial (EC). Ubamatamab MUC16 × cluster of differentiation 3 (MUC16×CD3) bispecific antibody bridges on tumor cells CD3 T to promote T-cell–mediated cytotoxicity. Cemiplimab, monoclonal targeting the programmed death-1 (PD-1) receptor, enhanced MUC16×CD3 activity preclinical models. In Phase 1 this first-in-human study (NCT03564340), ubamatamab alone combination with...
본 연구는 지역 삶의 질 지표의 효과적인 개발과 측정을 위해 지역주민의 질에 대한 인식조사가 이루어져야 하고 지표 개발과정에 시민참여가 증대될 필요가 있음을 밝히고자 한다. Q 방법론을 활용한 질과 관련한 총 50개의 진술문을 구성하고 대전지역 주민 32명을 대상으로 인식을 조사하였다. 결과적으로 주민의 세 가지 유형으로 구분하였다. 물질적 조건보다 비물질적 조건을 중시하지만 사회환경적 문제를 외면하고 개인적 범위에 한정되어 있는 ‘개인 만족 집중, 사회문제 소홀형’, 중시하며 가깝게 머물러 있으나 사회문제를 직시하고 불안함을 느끼는 중시, 직시형’, 개인보다 사회, 환경적 범위와 영역과 조건과 영역을 중요시하는 ‘사회, 환경 중시형’이다. 유형 모두 있어서 공통적으로 가족, 친구 및 이웃과의 관계와 자기결정력, 유데모니아와 같은 주관적 측면의 요소에 중요도가 높게 나타났다. 향후 연구 결과를 반영하여 지표개발이 구체적이고 심도 있게 함을 제안한다.