A5101619876- Inflammatory Myopathies and Dermatomyositis
- Dementia and Cognitive Impairment Research
- Parkinson's Disease Mechanisms and Treatments
- Machine Learning in Healthcare
- Epigenetics and DNA Methylation
- Ovarian cancer diagnosis and treatment
- Colorectal Cancer Treatments and Studies
- Diamond and Carbon-based Materials Research
- Folate and B Vitamins Research
- Colorectal Cancer Screening and Detection
- Radiomics and Machine Learning in Medical Imaging
- Alzheimer's disease research and treatments
- Iron Metabolism and Disorders
- Amyotrophic Lateral Sclerosis Research
- Metabolism and Genetic Disorders
- TiO2 Photocatalysis and Solar Cells
- Mitochondrial Function and Pathology
- Erythropoietin and Anemia Treatment
- Quantum Dots Synthesis And Properties
- Eosinophilic Disorders and Syndromes
- AI in cancer detection
- Lipoproteins and Cardiovascular Health
- Mollusks and Parasites Studies
- Geological Formations and Processes Exploration
- Preterm Birth and Chorioamnionitis
Xinjiang Technical Institute of Physics & Chemistry
2025
Chinese Academy of Sciences
2025
University of Chinese Academy of Sciences
2025
Qilu Hospital of Shandong University
2020-2025
Shandong University
2018-2024
The University of Texas Health Science Center at Houston
2022-2024
Jilin University of Chemical Technology
2024
Zhengzhou University
2010-2022
Third Affiliated Hospital of Zhengzhou University
2017-2022
Second Military Medical University
2022
Abstract Pulmonary embolism (PE) is a blood clot traveling to the lungs and associated with substantial morbidity mortality. Therefore, rapid diagnoses treatments are essential. Chest computed tomographic pulmonary angiogram (CTPA) gold standard for PE diagnoses. Deep learning can enhance radiologists’workflow by identifying using CTPA, which helps prioritize important cases hasten at-risk patients. In this study, we propose two-phase multitask method that recognize presence of its...
Roxadustat is a novel hypoxia- inducible factor-prolyl hydroxylase inhibitor(HIF-PHI) used to treat anemia in chronic kidney disease (CKD) patients. It has been reported that roxadustat can slow down damage and delay the development of fibrosis. Anemia iron deficiency are often associated with vast majority CKD patients, insufficient available or total storage most common cause ESAs resistance The role availability pathogenesis received increasing attention. To explore whether combined...
The capability of zero-order waveplates to manipulate the polarization fundamental-frequency light has garnered significant attention in rapid advancements laser technology. In particular, waveplate materials...
Abstract The higher prevalence of metabolic syndrome (MetS) in women after menopause is associated with a decrease circulating 17β-oestradiol. To explore novel treatments for MetS oestrogen deficiency, we studied the effect exogenous butyrate on diet-induced obesity and dysfunctions using ovariectomized (OVX) mice as model. Oral administration sodium (NaB) reduced body fat content blood lipids, increased whole-body energy expenditure, improved insulin sensitivity. Additionally, NaB induced...
To explore the clinical characteristics of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) caused by DNA-encoded complex I subunit (mt-ND) variants.In this retrospective study, clinical, myopathological brain MRI features patients with MELAS mt-ND variants (MELAS-mtND) were collected compared those carrying m.3243A > G variant (MELAS-A3243G).A total 18 MELAS-mtND (female: 7; median age: 24.5 years) represented 15.9% (n = 113) all mtDNA in our neuromuscular...
The graphene aggregates films were fabricated directly on Fe‐Cr‐Ni alloy substrates by microwave plasma chemical vapor deposition system (MPCVD). source gas was a mixture of H 2 and CH 4 with flow rates 100 sccm 12 sccm, respectively. micro‐ nanostructures the samples characterized Raman scattering spectroscopy, field emission scanning electron microscopy (SEM), transparent (TEM). properties measured using diode structure in vacuum chamber. turn‐on about 1.0 V/ μ m. current density 2.1 mA/cm...
We used a dataset from cross-sectional survey conducted in China to determine which of the anthropometric indices obesity are important terms carotid atherosclerosis free cardiovascular and cerebrovascular diseases.A total 5,245 participants who were volunteering for ultrasound unit this included present analysis. All subjects angina, myocardial infarction, heart failure stroke, cancer. A low-risk subgroup was defined as people hypertension, diabetes, hyperlipidemia. analyses based on...
The lung is the most common distant metastatic organ in patients with endometrial cancer (EC) but rarely reported. This study examines association between clinical characteristics and overall survival (OS) EC metastasis.Patients who had accompanying metastasis were selected from Surveillance, Epidemiology, End Results (SEER) database 2010 2017. Univariate multivariate Cox regression used to estimate hazard ratios (HRs) 95% confidence intervals (95% CIs) assess OS outcomes related metastasis....
The rate of progression Alzheimer's disease (AD) differs dramatically between patients. Identifying the most is critical because when their numbers differ treated and control groups, it distorts outcome, making impossible to tell whether treatment was beneficial. Much recent effort, then, has gone into identifying RPs. We pooled de-identified placebo-arm data three randomized controlled trials (RCTs), EXPEDITION, EXPEDITION 2, 3, provided by Eli Lilly Company. After processing, included 1603...
Background Estimates of survival after curative colorectal cancer (CRC) surgery are the basis patient care and treatment planning. A nomogram is a useful tool for individualized prognosis. Methods total 2450 patients with nonmetastatic CRC were included to develop nomogram. Prognostic factors identified integrated by Cox proportional hazards model. Then, we developed validated prognostic The performance this model was assessed concordance index (C‐index) calibration curve. internally...
Neuroimaging studies of hippocampal volumes in patients with amyotrophic lateral sclerosis (ALS) have reported inconsistent results. Our aims were to demonstrate that such discrepancies are largely due atrophy different regions the hippocampus emerge disease stages ALS and explore existence co-pathology patients. We used well-validated King’s clinical staging system for classify into stages. investigated vivo patterns across subfields anterior-posterior segments using structural MRI 76 94...
Background: Early cognitive impairment after transient ischemic stroke (TIA)/mild (MIS) is common but easily overlooked. It has been demonstrated that DNA methylation plays a significant role in and stroke. Furthermore, it reported the RIN3 gene influences transportation of amyloid β-protein. However, to our knowledge, there no research related correlations between early-onset TIA/MIS. Therefore, this study aimed investigate relationship TIA/MIS patients. Methods: This include 28 control...
Many patients with colorectal cancer are elderly competing comorbidities. When constructing nomogram for assessing survival, we should consider the influence of risk. A competing-risks was developed to estimate probability death due after curative surgery.A total 2442 non-metastatic were included develop nomogram. Competing-risks established based on results Fine and Gray proportional hazards model. To maximize accuracy prediction, model selection not carried out, non-linear continuous...
Hepcidin is an essential regulator of iron homeostasis in chronic kidney disease (CKD) anemia, reticulocyte hemoglobin equivalent (RET-He) can be used to evaluate the availability for erythropoiesis. Previous research has found that hepcidin indirectly regulates RET-He. This study aimed investigate association hepcidin, RET-He and anemia-related indicators on anemia disease. A total 230 individuals were recruited, including 40 CKD3-4 patients, 70 CKD5 patients without renal replacement...
Abstract Alzheimer’s disease (AD) is a multifaceted neurodegenerative disorder with varied patient progression. We aim to test the hypothesis that AD patients can be categorized into subgroups based on differences in leveraged data from three randomized clinical trials (RCTs) develop knowledge-guided, deep temporal clustering (KG-DTC) framework for subtyping. This model combined autoencoders contextual information capture, k-means representation formation, and outcome classification...