Xingchen Du

ORCID: 0009-0007-0288-9586
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Research Areas
  • Gout, Hyperuricemia, Uric Acid
  • Alcohol Consumption and Health Effects
  • Case Reports on Hematomas
  • Liver physiology and pathology
  • Thin-Film Transistor Technologies
  • Fire effects on concrete materials
  • MicroRNA in disease regulation
  • Cardiac Fibrosis and Remodeling
  • Kruppel-like factors research
  • Pharmacological Effects of Natural Compounds
  • Nanowire Synthesis and Applications
  • Advanced Malware Detection Techniques
  • Hippo pathway signaling and YAP/TAZ
  • Wnt/β-catenin signaling in development and cancer
  • Rabies epidemiology and control
  • Connective tissue disorders research
  • Cell Adhesion Molecules Research
  • Aortic aneurysm repair treatments
  • Plasmonic and Surface Plasmon Research
  • Antimicrobial Peptides and Activities
  • Structural Load-Bearing Analysis
  • Cell Image Analysis Techniques
  • Cancer, Hypoxia, and Metabolism
  • Structural Behavior of Reinforced Concrete
  • Liver Disease and Transplantation

Shenzhen Technology University
2024

Fudan University
2023-2024

Huashan Hospital
2023-2024

Ningxia Medical University
2019-2021

Monash University
2021

Beijing Normal University
2017

Abstract Objective Spontaneous serum uric acid (SUA) decrease has been found in many patients during acute gout attacks, but its mechanism remains unclear. Methods The spontaneous regulation of SUA a attack and possible causes were evaluated with gout. the was further studied Caco2 cells monosodium urate (MSU)-induced model wild-type mice ABCG2−/− mice. transport function intestinal epithelial detected by transwell culture cells. Expression ATP-binding cassette super-family G member 2...

10.1093/rheumatology/kead139 article EN Lara D. Veeken 2023-04-12

Vaccination is the most feasible way of preventing rabies, an ancient zoonosis that remains a major public health concern globally. However, administration inactivated rabies vaccination without adjuvants always inefficient and necessitates four to five injections. In current study, we explored adjuvant characteristics cordycepin, bioactive component Cordyceps militaris, boost immune responses against commercially available vaccine. We found cordycepin could stimulate stronger phenotypic...

10.1016/j.heliyon.2024.e24612 article EN cc-by-nc-nd Heliyon 2024-01-01

Abstract Objective To construct a risk prediction model for atherosclerotic cardiovascular disease (ASCVD) in patients with hyperuricemia. Methods Data this study were obtained from the National Health and Nutrition Examination Survey (NHANES) (2007–2010). Participants Huashan Hospital included as an external validation. Logistic regression analysis was used to explore relevant factors of ASCVD The discriminability evaluated using area under curve (AUC) statistic receiver operating...

10.1111/1756-185x.15205 article EN International Journal of Rheumatic Diseases 2024-06-01

Enhancing the light absorption in thin film silicon solar cells with nanophotonic and plasmonic structures is important for realization of high efficiency significant cost reduction. In this work, we investigate periodic arrays conformal metal/silicon nanobowl (MSNBs) trapping applications cells. They exhibited excellent light-harvesting ability across a wide range wavelengths up to infrared regimes. The optimized structure (MSNBsH) covered by SiO 2 passivation layer hemisphere Ag back...

10.1155/2017/4270794 article EN Journal of Nanomaterials 2017-01-01

Abstract Hyperuricemia is a common metabolic disorder with severe complications. We aimed to develop mouse model for spontaneous hyperuricemia. Uox -/- was generated on C57BL/6J background by deleting exon 2-4 of using the CRISPR/Cas9 system. The prototypic mice had 5.5-fold increased serum uric acid (1351.04±276.58μmol/L) as compared wild type ( P <0.0001), but died 4 weeks. After allopurinol (3ug/g) intervention, they all survived > 8 612.55±146.98μmol/L in 8-week-old...

10.1007/s12265-024-10526-6 article EN cc-by Journal of Cardiovascular Translational Research 2024-06-10

Abstract Objective To construct a prediction model for renal involvement in patients with hyperuricemia (HUA) based on logistic regression analysis, to achieve early risk stratification. Method In this cross‐sectional study, we collected data from the National Health and Nutrition Examination Survey (NHANES), constructed predicted HUA patients. The discriminative ability of was assessed using receiver operating characteristic (ROC) curve. Model accuracy evaluated Hosmer‐Lemeshow test...

10.1111/1756-185x.15374 article EN International Journal of Rheumatic Diseases 2024-10-30

Abstract Owing to its superior performance at high temperatures, stainless steel is usually considered as a potential replacement for mild in wide range of structural fire engineering applications. When it comes the design structures, time‐dependent deformations occurring adequately‐heated material, called “thermal creep” need be somehow calculations. In EUROCODE 3‐1‐2, example, thermal creep strains are implicitly included transiently‐determined stress‐strain curves elevated temperatures....

10.1002/cepa.1434 article EN ce/papers 2021-09-01
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