A5100737088- Olfactory and Sensory Function Studies
- Memory and Neural Mechanisms
- Neural dynamics and brain function
- Nanoplatforms for cancer theranostics
- Software System Performance and Reliability
- Nanoparticle-Based Drug Delivery
- Cancer Research and Treatments
- Photoreceptor and optogenetics research
- Multi-Criteria Decision Making
- Luminescence and Fluorescent Materials
- Evaluation and Optimization Models
- Electric and Hybrid Vehicle Technologies
- Neural and Behavioral Psychology Studies
- Real-time simulation and control systems
- Collaboration in agile enterprises
- Value Engineering and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Green IT and Sustainability
- Catalysis for Biomass Conversion
- Particle physics theoretical and experimental studies
- Real-Time Systems Scheduling
- IoT and Edge/Fog Computing
- Neural Networks and Applications
- Photoacoustic and Ultrasonic Imaging
- Biofuel production and bioconversion
Jimei University
2025
Beihang University
2023-2024
Sichuan Agricultural University
2024
Leshan Normal University
2024
Center for Excellence in Brain Science and Intelligence Technology
2018-2023
Chinese Academy of Sciences
2014-2023
Institute of High Energy Physics
2023
Shanghai Center for Brain Science and Brain-Inspired Technology
2019-2020
Shanghai Institutes for Biological Sciences
2014-2018
Nanjing University
2017
Cognitive processes require working memory (WM) that involves a brief period of retention known as the delay period. Elevated delay-period activity in medial prefrontal cortex (mPFC) has been observed, but its functional role WM tasks remains unclear. We optogenetically suppressed or enhanced pyramidal neurons mouse mPFC during Behavioral performance was impaired learning phase not after mice were well trained. Delay-period appeared to be more important than inhibitory control,...
Abstract Anaerobic bacteria, such as Clostridium and Salmonella , can selectively invade colonize in tumor hypoxic regions (THRs) deliver therapeutic products to destroy cancer cells. Herein, we present an anaerobe nanovesicle mimic that not only be activated THRs but also induce hypoxia tumors by themselves. Moreover, inspired the oxygen metabolism of anaerobes, construct a light‐induced hypoxia‐responsive modality promote dissociation vehicles activation bioreductive prodrugs...
Working memory is a critical brain function for maintaining and manipulating information over delay periods of seconds. It debated whether delay-period neural activity in sensory regions important the active maintenance during period. Here, we tackle this question by examining anterior piriform cortex (APC), an olfactory cortex, head-fixed mice performing several working tasks. Active necessary these tasks, especially dual-task paradigm which are required to perform another distracting task...
Practical application of brain-computer interfaces (BCIs) requires stable mapping between neuronal activity and behavior through various behavioral contexts for different individuals. Due to neural instability, BCIs require frequent recalibration maintain robust performance. Early approaches addressing BCI stability issues mainly focused on tackling the challenge changes over time. However, future applications involve diversified scenarios subjects, requiring solutions that address...
Understanding neuronal mechanisms of learned behaviors requires efficient behavioral assays. We designed a high-throughput automatic training system (HATS) for olfactory in head-fixed mice. The hardware and software were constructed to enable with minimal human intervention. integrated was composed customized 3D-printing supporting components, an odor-delivery unit fast response, Arduino based hardware-controlling data-acquisition unit. Furthermore, the all phases, including lick-teaching,...
Abstract Anaerobic bacteria, such as Clostridium and Salmonella , can selectively invade colonize in tumor hypoxic regions (THRs) deliver therapeutic products to destroy cancer cells. Herein, we present an anaerobe nanovesicle mimic that not only be activated THRs but also induce hypoxia tumors by themselves. Moreover, inspired the oxygen metabolism of anaerobes, construct a light‐induced hypoxia‐responsive modality promote dissociation vehicles activation bioreductive prodrugs...
Levulinic acid, a hydrolysis product of lignocellulose, can be metabolized into important compounds in the field medicine and pesticides by engineered strains Saccharomyces cerevisiae. as an intermediate widely found conversion process lignocellulosic biomass, has multiple applications. However, its toxicity to cerevisiae reduces efficiency, so screening genes that tolerate levulinic acid becomes key. By creating whole-genome knockout library bioinformatics analysis, this study used...
A determination of the $CP$-even fraction ${F}_{+}$ in decay ${D}^{0}\ensuremath{\rightarrow}{K}^{+}{K}^{\ensuremath{-}}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ is presented. Using $2.93\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ ${e}^{+}{e}^{\ensuremath{-}}\ensuremath{\rightarrow}\ensuremath{\psi}(3770)\ensuremath{\rightarrow}D\overline{D}$ data collected by BESIII detector, one charm meson reconstructed signal mode and other a $CP$ eigenstate or...
Abstract How does millisecond-scale neural activity mediate behaviors over seconds? We recorded brain-wide in mice performing an olfactory working-memory task to decipher cross-region organization of activity. Spike-correlograms revealed millisecond within- and spike couplings, more prominent among neurons encoding similar memories. Spike coupling linked into motifs chains, single loops, nested especially hippocampal prefrontal-cortex neurons. Direction chains was line with that...
Android mobile devices have been suffering from performance degradation and increased failure rates during long-term operation, known as software aging. With the major changes in optimization resource management Android, it is spotted that aging behavior of 2020s differs significantly previous studies utilization metrics, which makes some classic metrics difficult to measure well, new are required better describe phenomenon. Thus, we propose thread- interface-level portray at a finer...
Summary Working memory is a critical function of the brain to maintain and manipulate information over delay periods seconds. Sensory areas have been implicated in working memory; however, it debated whether delay-period activity sensory regions actively maintaining or passively reflecting top-down inputs. We hereby examined anterior piriform cortex, an olfactory head-fixed mice performing series tasks. Information maintenance necessary these tasks, especially dual-task paradigm which are...
In the view of fuzzy characteristics corporate social responsibility (CSR), this paper put lifecycles theory into CSR and stakeholder by mathematics method.Based on above, get four relation matrixes: cycle comprehensive ability, degree, specific responsibilities, stakeholders' eventually construct model matching with based lifecycle: QS QR model.Finally, numerical examples are also considered provide some guidance for corporations.
In the view of fuzzy characteristics corporate social responsibility (CSR), this paper put lifecycles theory into CSR and stakeholder by mathematics method. Based on above, get four relation matrixes: cycle comprehensive ability, degree, specific responsibilities, stakeholders' eventually construct model matching with based lifecycle: QS QR model. Finally, numerical examples are also considered provide some guidance for corporations.
Abstract Understanding neuronal mechanisms of cognitive behaviors requires efficient behavioral assays. We designed a high-throughput automatic training system (HATS) for olfactory in head-fixed mice. The hardware and software were constructed to enable with minimal human intervention. integrated was composed customized 3D-printing supporting components, an odor-delivery unit fast response, Arduino based hardware-controlling data-acquisition unit. Furthermore, the all phases, including...