- Epilepsy research and treatment
- Intracranial Aneurysms: Treatment and Complications
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Spinal Dysraphism and Malformations
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Fetal and Pediatric Neurological Disorders
- Vagus Nerve Stimulation Research
- Neurological disorders and treatments
- Neurological Complications and Syndromes
- Childhood Cancer Survivors' Quality of Life
- Bacterial Infections and Vaccines
- Moyamoya disease diagnosis and treatment
- Advanced Neuroimaging Techniques and Applications
- Botulinum Toxin and Related Neurological Disorders
- Pharmacological Effects and Toxicity Studies
- Ocular Oncology and Treatments
- Tracheal and airway disorders
- Ophthalmology and Eye Disorders
- Infectious Diseases and Tuberculosis
- Streptococcal Infections and Treatments
- Cerebral Palsy and Movement Disorders
- Pituitary Gland Disorders and Treatments
Texas Children's Hospital
2016-2025
Baylor College of Medicine
2012-2024
Neurological Surgery
2020-2024
Oxford University Press (United Kingdom)
2018
The University of Texas MD Anderson Cancer Center
2012
Abstract BACKGROUND Hypothalamic hamartomas (HH) are a challenging pathology that cause gelastic seizures. Magnetic Resonance Imaging-guided Laser Interstitial Thermal Therapy (MRgLITT) offers safe and effective treatment for HHs via minimally invasive technique. OBJECTIVE To determine how clinical outcome correlates to residual tumor volume surgical strategy by analyzing radiographic data reconstructing volumetric imaging. METHODS Clinical information of 58 pediatric patients who underwent...
Deep brain stimulation of the centromedian nucleus thalamus (CM-DBS) is an investigational, off-label treatment for drug-resistant epilepsy (DRE) in children. Although emerging evidence supports its safety and efficacy select indications, effect CM-DBS on quality life functional outcomes such as school attendance has not been studied. Here, we analyzed data from prospective CHILD-DBS (Child & Youth Comprehensive Longitudinal Database Brain Stimulation) to examine impact patient-...
Brain abscess carries a high morbidity and mortality despite medical advances. In this paper, we present single institution's experience with the surgical treatment of brain abscess.We retrospectively analyzed 33 cases intracranial who underwent between January 2001 December 2009. Patients were treated aspiration through burr hole, open ultrasound guidance, or complete resection. The records for demographics, clinical presentation, predisposing factors, imaging, microbiological...
Cerebellar mutism syndrome (CMS) refers to constellation of symptoms noted most commonly following surgery for posterior fossa tumors in the pediatric population. Mutism is a prominent, though not exclusive, characteristic and was first described 1985 by Rekate et al.[27] In their paper, authors six children ranging from 1 6 years age who developed complete absence speech resection masses. Loss transient all patients this series, many subsequent descriptions has been long lasting.[15,31,32]...
OBJECTIVENumerous surgical procedures facilitate revascularization of the ischemic brain in patients with moyamoya disease. Dural inversion is a technique which flaps dura mater centered around middle meningeal artery are inverted, encouraging formation rich collateral blood supply. This procedure has been used combination encephaloduroarteriosynangiosis for more than 20 years at authors' institution treatment pediatric The objective this study was to describe clinical and radiographic...
Objective To evaluate the results of endoscopic transnasal resection tuberculum sellae meningiomas (TSMs) as compared with transcranial approaches. Design We retrospectively analyzed five patients who underwent endonasal TSM and performed a comprehensive review articles published between 2000 2012 describing operative treatment TSMs. Results Gross total (GTR) was achieved in four (80%). Transient diabetes insipidus occurred three (60%). Preoperative visual field deficit resolved all...
Gangliogliomas (GGs) are rare tumors of the central nervous system composed neoplastic neural and glial cells typically low-grade. Intramedullary spinal anaplastic GGs (AGG) rare, poorly understood, often aggressive that can result in widespread progression along craniospinal axis. Due to rarity these tumors, data lacking guide clinical pathologic diagnosis standard care treatment. Here, we present a case pediatric AGG provide information on our institutional approach work-up highlight...
BACKGROUND The intrathecal baclofen pump is an effective treatment option for patients with severe spasticity. In children, subfascial placement often preferred given concerns infection and wound healing. However, this approach not without risk, rare complications, such as peritoneal migration, can occur. OBSERVATIONS authors describe three pediatric cases of migration at their institution over the past 14 years (3/545, 0.5%). All had low body weight (below 39th percentile), two scoliosis...
Resection of posterior fossa tumors in children may be associated with persistent neurological deficits. It is unclear if these deficits are structural damage to the cerebellar pathways. The purpose this research was define longitudinal changes diffusion tensor imaging (DTI) metrics white matter tracts and clinical correlates undergoing resection tumors.
OBJECTIVE In utero repair of fetal posterior cephaloceles (meningocele and encephalocele) is being performed based on the premise that surgery prevents progressive herniation neural tissue brain damage during pregnancy. However, extent to which occurs pregnancy, specifically from prenatal diagnosis after delivery, not well known. The objective this study was describe natural history patients with focusing incidence herniation. METHODS authors conducted a retrospective cohort all referred...
OBJECTIVE Moyamoya disease is a progressive occlusive arteriopathy for which surgical revascularization indicated. In this retrospective study, the authors investigated use of preoperative CT perfusion with aim establishing pathological data references. METHODS The reviewed medical records children moyamoya treated surgically at one institution between 2016 and 2019. Preoperative studies were used to quantify mean transit time (MTT), cerebral blood volume (CBV), flow (CBF), peak (TTP)...