Nicholas Sédillot
A5109585659- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Sepsis Diagnosis and Treatment
- Family and Patient Care in Intensive Care Units
- COVID-19 and Mental Health
- Cardiac Arrest and Resuscitation
- SARS-CoV-2 and COVID-19 Research
- Healthcare Decision-Making and Restraints
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Anesthesia and Sedative Agents
- Peripheral Neuropathies and Disorders
- Viral Infections and Outbreaks Research
- Dialysis and Renal Disease Management
- Palliative Care and End-of-Life Issues
- Machine Learning in Healthcare
- Posttraumatic Stress Disorder Research
- Healthcare professionals’ stress and burnout
- Airway Management and Intubation Techniques
- Diabetes Management and Research
- Heart Failure Treatment and Management
- Infectious Encephalopathies and Encephalitis
- Myasthenia Gravis and Thymoma
Inserm
2022-2023
The University of Queensland
2023
All India Institute of Medical Sciences Raipur
2023
All India Institute of Medical Sciences Rishikesh
2023
Centre de recherche en Epidémiologie et Santé des Populations
2023
Université de Versailles Saint-Quentin-en-Yvelines
2023
Centre Hospitalier de Versailles
2023
Centre Hospitalier Universitaire de Rennes
2022
Centre Hospitalier Universitaire de Nantes
2022
Université de Poitiers
2022
Importance The benefit of high-flow nasal cannula oxygen (high-flow oxygen) in terms intubation and mortality patients with respiratory failure due to COVID-19 is controversial. Objective To determine whether the use oxygen, compared standard could reduce rate at day 28 admitted intensive care units (ICUs). Design, Setting, Participants SOHO-COVID randomized clinical trial was conducted 34 ICUs France included 711 a ratio partial pressure arterial fraction inspired equal or below 200 mm Hg....
Spontaneous-breathing trials can be performed with the use of either pressure-support ventilation (PSV) or a T-piece. Whether PSV may result in shorter time to tracheal extubation than T-piece trials, without resulting higher risk reintubation, among patients who have high failure is unknown.In this multicenter, open-label trial, we randomly assigned had (i.e., were >65 years age an underlying chronic cardiac respiratory disease) undergo spontaneous-breathing (with level 8 cm water and no...
Abstract Background We investigated the impact of COVID-19 crisis on mental health professionals working in intensive care unit (ICU) according to intensity epidemic France. Methods This cross-sectional survey was conducted 77 French hospitals from April 22 May 13 2020. All ICU frontline healthcare workers were eligible. The primary endpoint health, assessed using 12-item General Health Questionnaire. Sources stress during Perceived Stressors Intensive Care Units (PS-ICU) scale. Epidemic...
Introduction The optimal method for removing the endotracheal tube (ETT) during extubation in intensive care unit (ICU) remains uncertain. Two methods are described ETT ICU, namely ‘Traditional technique’ with continuous aspiration cuff deflation and removal; ‘PEEP’ method, which consists applying positive end-expiratory pressure (PEEP) before removal. Our hypothesis is that PEEP ICU would improve clinical outcome. Methods analysis This a prospective, multicentre, randomised, open-label,...
<h3>Objective:</h3> To report the prevalence of acute encephalopathy and outcomes in patients with severe COVID-19, to identify determinants 90-day outcomes. <h3>Methods:</h3> Data from adults COVID-19 were prospectively collected for requiring intensive care unit management 31 university or university-affiliated six countries (France, USA, Colombia, Spain, Mexico, Brazil) between March September 2020. Acute was defined, as recently recommended, subsyndromal delirium delirium, a comatose...
The objective of the study was to describe a five-step protocol for withholding and withdrawing life support (WH/WDLS) in an emergency department (ED) terminally ill patients.An observational conducted ED general hospital.A total 98 patients were admitted over 1-year period.The healthcare team chose pattern treatment limitation on basis every patient, which comprised five groups: group 1: there no care, 2: do not resuscitate order followed, 3: administration therapies without treating acute...
Introduction In intensive care unit (ICU), the decision of extubation is a critical time because mortality particularly high in case reintubation. To reduce that risk, guidelines recommend to systematically perform spontaneous breathing trial (SBT) before order mimic postextubation physiological conditions. SBT usually performed with T-piece disconnecting patient from ventilator or low levels pressure-support ventilation (PSV). However, work lower during PSV than T-piece. Consequently, while...
Introduction Prognosis of patients with COVID-19 depends on the severity pulmonary affection. The most severe cases may progress to acute respiratory distress syndrome (ARDS), which is associated a risk long-term repercussions function and neuromuscular outcomes. functional forms have major impact quality life, impair ability return work or exercise. Social inequalities in healthcare influence prognosis, socially vulnerable individuals more likely develop disease. We describe here protocol...
Stress hyperglycemia can persist during an intensive care unit (ICU) stay and result in prolonged requirement for insulin (PRI). The impact of PRI on ICU patient outcomes is not known. We evaluated the relationship between Day 90 mortality patients without previous diabetic treatments.This a post hoc analysis CONTROLING trial, involving 12 French ICUs. Patients personalized glucose control arm with length ≥ 5 days who had never previously received treatments (oral drugs or insulin) were...
First-line oxygenation strategy in patients with acute hypoxaemic respiratory failure consists standard oxygen or high-flow nasal therapy. Clinical practice guidelines suggest the use of rather than oxygen. However, findings remain contradictory a low level certainty. We hypothesise that compared oxygen, may reduce mortality failure.
<h3>Background</h3> For patients hospitalised in our intensive care unit (ICU), continuous venovenous haemofiltration (CVVH) with citrate has been implemented since 2013. This study was conducted to assess the change practices and restitution fluids (RF), analysing impact on consumption costs. Reflection this between physicians, nurses pharmacists. <h3>Purpose</h3> The aim of cost implications anticoagulation. <h3>Material methods</h3> We performed a retrospective ICU requiring CVVH 2014....