A5101974429- Ocular Surface and Contact Lens
- Air Quality and Health Impacts
- Immune Response and Inflammation
- Corneal Surgery and Treatments
- Climate Change and Health Impacts
- CAR-T cell therapy research
- COVID-19 impact on air quality
- Nitric Oxide and Endothelin Effects
- Ion channel regulation and function
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune Cell Function and Interaction
- Microbial Inactivation Methods
- Biosimilars and Bioanalytical Methods
- Immune cells in cancer
- Air Quality Monitoring and Forecasting
- Cancer Immunotherapy and Biomarkers
- stochastic dynamics and bifurcation
- Olfactory and Sensory Function Studies
- Psoriasis: Treatment and Pathogenesis
- Natural Compounds in Disease Treatment
- Neuroscience and Neural Engineering
- Electrochemical Analysis and Applications
- Corneal surgery and disorders
- Endoplasmic Reticulum Stress and Disease
- Gold and Silver Nanoparticles Synthesis and Applications
Zhejiang University
2023
Second Affiliated Hospital of Zhejiang University
2020-2023
Nankai University
2023
Beijing University of Technology
2022
Hebei Normal University
2021
University of Chicago
2006
University of Illinois Chicago
1998
Despite recent progress in non-small-cell lung cancer (NSCLC) treatment, treatment outcomes remain poor, mainly because of resistance or toxicity. Erastin is a ferroptosis inducer that has shown promising cytotoxic effects various types cancers, including NSCLC. Celastrol triterpene extracted from the Tripterygium wilfordii exhibits potential anticancer activity. However, side celastrol are severe and limit its clinical application. Combination therapy strategy to overcome compensatory...
Toll-like receptors (TLRs) recognize a set of conserved molecular structures, so called pathogen-associated patterns, which allow them to sense and initiate innate adaptive immune responses. In this study, we examined the expression TLRs in both human murine glioma. We then analyzed change TLR after treatment with synthetic phosphorothioate oligodeoxynucleotides (ODNs) containing unmethylated CpG dinucleotides (CpG ODNs), strong activators immunity. addition, investigated vivo effect...
Surface-enhanced Raman scattering (SERS) is a rapid and nondestructive spectroscopic method for trace detection. The enhancement based on both electromagnetic chemical mechanism requires the molecules to be in close contact with SERS-active material. Therefore, it difficult detect amounts of liquid directly. In this paper, graphene oxide (GO) Ag nanoparticles (AgNPs) are uniformly modified inner wall capillary. GO can provide by adsorbing analyte onto its flat surface producing efficient...
The association between air pollution and retinal diseases such as age-related macular degeneration (AMD) has been demonstrated, but the pathogenic correlation is unknown. Damage to outer blood-retinal barrier (oBRB), which consists of pigment epithelium (RPE) choriocapillaris, crucial in development fundus diseases.
Limbal stem/progenitor cells (LSPCs) play a crucial role in maintaining corneal health by regulating epithelial homeostasis. Although PM2.5 is associated with the occurrence of several diseases, its effects on LSPCs are not clearly understood.
To investigate the efficacy of intense pulsed light (IPL) combined with deproteinized calf blood extract (DCBE) eye drops for dry disease (DED) patients nociceptive ocular pain.In this prospective, one-center, interventional study, 23 subjects DED and pain were treated a combination IPL DCBE four sessions at four-week interval. Subjective objective assessments on examined analyzed.The visual analog scale (VAS), surface index, assessment survey (OPAS), patient health questionnaire-9 items,...
Tumor infiltration, known to associate with various cancer initiations and progressions, is a promising therapeutic target for aggressive cutaneous melanoma. Then, the relative infiltration of 24 kinds immune cells in melanoma was assessed by single sample gene set enrichment analysis (ssGSEA) program from public database. The multiple machine learning algorithms were applied evaluate efficiency diagnosing predicting prognosis In comparison expression cell tumor normal control, we built...
Antigen-presenting cells (APCs) constantly express major histocompatibility complex II (MHC II), including macrophages and dendritic (DCs) which deliver antigens to CD4+ T play an important role in adaptive immunity. The expression of MHC is controlled by the transcriptional coactivator CIITA. Interleukin-27 (IL-27), a newly discovered IL-12 family cytokine, composed p28 EBI3 subunits. In this study, we used IL-27p28 conditional knock-out mice investigate regulatory effects on macrophage...
Abstract Background The association between air pollution and retinal diseases such as age-related macular degeneration (AMD) has been demonstrated, but the pathogenic correlation is unknown. Damage to outer blood–retinal barrier (oBRB), which consists of pigment epithelium (RPE) choriocapillaris, crucial in development fundus diseases. Objectives To describe effects airborne fine particulate matter (PM 2.5 ) on oBRB disease susceptibilities. Methods A PM -exposed mice model was established...