A5101019766- Organ Transplantation Techniques and Outcomes
- Inflammasome and immune disorders
- Mesenchymal stem cell research
- interferon and immune responses
- Viral Infections and Vectors
- Liver Disease and Transplantation
- Intensive Care Unit Cognitive Disorders
- Immune Cell Function and Interaction
- Ovarian function and disorders
- Cancer-related molecular mechanisms research
- Reproductive Biology and Fertility
- Extracellular vesicles in disease
- Natural product bioactivities and synthesis
- Anesthesia and Sedative Agents
- Neurological Disease Mechanisms and Treatments
- Organ and Tissue Transplantation Research
- Mycotoxins in Agriculture and Food
- Drug-Induced Hepatotoxicity and Protection
- Assisted Reproductive Technology and Twin Pregnancy
- Energy Load and Power Forecasting
- Boron Compounds in Chemistry
- Solar Radiation and Photovoltaics
- Circular RNAs in diseases
- Paraoxonase enzyme and polymorphisms
- Glioma Diagnosis and Treatment
Lanzhou University
2024
South China Agricultural University
2024
Tianjin Medical University
2024
Chuzhou University
2024
Anhui Medical University
2024
Tianjin First Center Hospital
2024
Fudan University
2023
University of Science and Technology Beijing
2023
Peking University First Hospital
2023
Peking University
2023
Abstract Objectives The aim of this study was to investigate the anti-tumor effect resveratrol (RSV) on glioblastoma (GBM) and its specific mechanism in improving inflammatory response tumor microenvironment. microenvironment GBM is highly neuroinflammatory, inducing immunosuppression. Therefore, ameliorating an important focus for research. Methods RSV demonstrated through vitro cellular assays, including CCK-8, EdU, PI staining, Transwell, wound healing assay, flow cytometry. Potential...
Abstract Diazepam poisoning is a common emergency situation, but propafenone relatively rare. We reported case of combined with diazepam. An 18‐year‐old female patient was admitted to our hospital an overdose oral and The treated medication that proved be useful, the sinus rhythm could not recovered, cardiac arrest occurred. A bipolar temporary pacemaker extracorporeal membrane oxygenation (ECMO) were installed. However, even multiple electrode positions, effective capture achieved....
Melatonin (MT) has been shown to protect against various cardiovascular diseases. However, the effect of MT on lipopolysaccharide (LPS)-induced myocardial injury is poorly understood. This study aims evaluate effects LPS-induced in vitro.H9C2 cells were divided into a control group, LPS and + group. The group was treated with sterile saline solution, received 8 µg/mL for 24 h, pretreated 200 µmol/L 2 h then only h. CCK-8 assay lactate dehydrogenase (LDH) activity used analyze cell viability...
Nicotine contributes to the causation of atherosclerosis, which prominent cellular components are macrophages. Long non-coding RNAs (lncRNAs) play an important role in regulating cell functions such as proliferation, differentiation and programmed death. However, function mechanism lncRNAs nicotine-induced macrophage pyroptosis has not been reported. We screened deferentially expressed human carotid artery plaque (GSE97210) verified them Results showed only LINC01272 was up-regulated a...
Mammary gland hyperplasia (MGH) is a pathological condition that affects the majority of women at child-bearing stage. The hormone and endocrinal therapy are typically used to treat MGH. Nevertheless, there still some certain side effects accompanied with benefits, which negatively affect life quality patients. Therefore, plant-derived agents effective against MGH development fewer should be developed. aim this study was investigate protective underlying mechanism total saponins Phytolaccae...
In order to fully exploit the relationship between temporal features in photovoltaic power generation data and improve prediction accuracy of generation, a forecasting method is proposed based on hybrid model convolutional neural network (CNN) extreme gradient boost (XGBoost). Taking historical China’s plants as sample, high-dimensional mapping variables extracted layer pooling CNN construct time-series feature vector, which an input for XGBoost. A established CNN-XGBoost by training XGBoost...
The Na/K‑ATPase/Src complex is reportedly able to affect reactive oxygen species (ROS) amplification. However, it has remained elusive whether NADPH oxidases (NOXs) are involved in this oxidant amplification loop renal fibrosis. To test hypothesis, interactions between oxidative features and activation were examined a mouse model of unilateral urethral obstruction (UUO)‑induced experimental Both 1‑tert‑butyl‑3‑(4‑chlorophenyl)‑1H‑pyrazolo[3,4‑d]pyrimidin‑4‑amine (PP2) apocynin significantly...
Monosialoganglioside 1 (GM1) is the main ganglioside subtype and has neuroprotective properties in central nervous system. In this study, we aimed to determine whether GM1 alleviates neurotoxicity induced by moderate high concentrations of propofol combined with remifentanil immature Hippocampal neural stem cells were isolated from newborn Sprague-Dawley rats treated (5, 10, 20 ng/mL) (1.0, 2.5, 5.0 μg/mL), and/or (12.5, 25, 50 μg/mL). reversed remifentanil-induced decreases percentage...
It is now recognized that transplantation of bone marrow cells (BMCs) into infarcted hearts has the capacity to improve cardiac function through paracrine effects. However, detailed expression levels factors in BMCs are poorly described. By use laser capture microdissection combined with real-time PCR, we depicted profiles versus normal hearts. Consistent vivo observation, a similar pattern was evidenced cultured BMCs. Furthermore, displayed heterogeneity effects as analyzed at single cell...
Our study revealed the spatial interaction between humanized ACE2 and pseudovirus expressing Spike, emphasizing role of type 2 innate lymphoid cells during initial phase viral infection. These findings provide a foundation for development mucosal vaccines other treatment approaches both pre- post-infection management coronavirus disease 2019.
ABSTRACT Phosphatidylcholines (PCs) are a class of cell membrane phospholipids playing important roles in cellular integrity and signaling. In eukaryotes, PCs biosynthesized via the Kennedy cytidine nucleotide Bremer-Greenberg pathways. The Aspergillus choC gene is predicted to encode phospholipid methyltransferase, key enzyme latter pathway. this study, we have characterized opportunistic human pathogenic fungus fumigatus show that ChoC plays vital role endogenous biosynthesis PC, which...
Hypoxic-ischemic brain damage (HIBD) is a major cause of injury in neonates. Bone marrow mesenchymal stem cells (BMSCs) show therapeutic potential for HIBD, and genetic modification may enhance their neuroprotective effects. The goal this study was to investigate the effects hepatocyte growth factor (HGF)-overexpressing BMSCs (BMSCs-HGF) against HIBD underlying mechanisms.BMSCs were transfected with HGF using adenoviral vectors. models established then transplanted into brains rats via...
In this study, normal values of semen analysis were set for a general infertile population couples among which most women had ovulation. The predictive capacity sperm quality, including concentration, motile count, progressive and morphology, are unclear with polycystic ovary syndrome (PCOS). A secondary was conducted based on randomized controlled trial investigating infertility PCOS experiencing ovulatory disorder between 2011 2016 in China. total 1000 received ovulation induction...
：Objective Tocomparatively study the ischemia-reperfusion injuries caused by heterogeneity of differentpositions biliary system and different construction patterns peribiliaryvascular plexus. Methods Thirty rats were randomly divided into 3 groups: Group Ⅰ , sham operated; Ⅱ, 1h ischemia inbiliary tract followed reperfusion; Ⅲ, in biliarytract 2h reperfusion. TUNEL assay, pathomorphology score determination andultrastructural quantitative analysis performed on epithelium hilar bile...