A5089916107- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Management of metastatic bone disease
- Cancer Mechanisms and Therapy
- Gastrointestinal disorders and treatments
- Lipid metabolism and disorders
- Liver Disease and Transplantation
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Dermatological and COVID-19 studies
- Orthopaedic implants and arthroplasty
- Esophageal and GI Pathology
- Bone and Joint Diseases
- Hepatitis B Virus Studies
- History of Medicine Studies
- Heavy Metal Exposure and Toxicity
- Orthopedic Infections and Treatments
- Autophagy in Disease and Therapy
- Medical Imaging and Analysis
- Neurological Disorders and Treatments
- Spinal Fractures and Fixation Techniques
- Cancer Treatment and Pharmacology
- Cancer-related gene regulation
- Moyamoya disease diagnosis and treatment
University of South China
2020-2024
Wuxi People's Hospital
2024
Nanjing Medical University
2024
China Tobacco
2024
Ningxia Medical University
2024
Eastern Hepatobiliary Surgery Hospital
2022-2023
Second Military Medical University
2022-2023
University of Liverpool
2023
Zaozhuang University
2022
Hubei University of Chinese Medicine
2021
The incidence of hypertriglyceridemia-associated acute pancreatitis (HTG-AP) is increasing. Plasmapheresis theoretically effective in removing triglyceride from plasma, but whether it confers clinical benefits unclear.To assess the association between plasmapheresis and duration organ failure among patients with HTG-AP.This an a priori analysis data multicenter, prospective cohort study enrolled 28 sites across China. Patients HTG-AP were admitted within 72 hours disease onset. first patient...
No specific triglyceride-lowering therapy is recommended in patients with hypertriglyceridemia-associated acute pancreatitis (HTG-AP), primarily because of the lack quality evidence. This study aimed to describe practice variations therapies for early HTG-AP and assess whether more rapid triglyceride decline associated improving organ failure. a multicentre, prospective cohort recruiting elevated plasma (> 11.3 mmol/L) admitted within 72 h from onset symptoms. Patients were dichotomised on...
Background: Finding reliable diagnostic markers for gastric cancer (GC) is important. This work uses machine learning (ML) to identify GC genes and investigate their connection with immune cell infiltration. Methods: We downloaded eight GC-related datasets from GEO, TCGA, GTEx. GSE13911, GSE15459, GSE19826, GSE54129, GSE79973 were used as the training set, GSE66229 validation set A, TCGA & GTEx B. First, screened differentially expressed (DEGs), gene ontology (GO), kyoto encyclopedia of...
Primary liver cancer is a common and lethal malignancy in China. Transcatheter arterial chemoembolization (TACE) globally recognized as the preferred treatment modality for non-surgical resection of hepatocellular carcinoma (HCC), while transcatheter infusion (TAI) another effective interventional HCC. In recent years, hepatic chemotherapy (HAIC) has gained increasing attention an application-regulated TAI. Owing to current debate medical community regarding use HAIC TACE HCC, application...
Nucleus pulposus (NP) cell apoptosis is a typical feature within the degenerative disc. High magnitude compression significantly promotes NP apoptosis. Several studies have indicated that resveratrol has protective effects on disc cell's normal biology.
Abstract Background Plasmapheresis is widely used for severe hypertriglyceridemia-associated acute pancreatitis (HTG-AP) to remove excessive triglycerides from plasma. This study aimed evaluate whether plasmapheresis could improve the duration of organ failure in HTG-AP patients. Methods We analyzed a cohort patients multicenter, prospective, long-running registry (the PERFORM) collecting admitted sites within 72 h onset symptoms. was based on data collected November 2020 March 2023....
We report, for the first time, a case of pyogenic spondylodiscitis combined with vertebral osteomyelitis and bilateral psoas abscesses after acupuncture.A 60-year-old man was diagnosed rectal cancer, radical rectectomy permanent colostomy were carried out. However, 3 years surgery patient complained pain in lower back, symptoms worsened seven sessions acupuncture. Technetium 99m-labelled methylene diphosphonate ((99m)Tc-MDP) bone scintigraphy (BS) revealed abnormal uptake (99m)Tc-MDP L4 L5...
Introduction Infected pancreatic necrosis (IPN) and its related septic complications are the major causes of death in patients with acute necrotising pancreatitis (ANP). Therefore, prevention IPN is great clinical value, immunomodulatory therapy thymosin alpha 1 may be beneficial. This study was designed to test hypothesis that administration during phase ANP will result a reduced incidence IPN. Methods analysis randomised, multicentre, double-blind, placebo-controlled study. 520 eligible...
Jingshu Keli (or granules), a traditional Chinese medicine, are widely used for treating cervical spondylotic radiculopathy in China; however, no randomized, double-blind, controlled study has verified their effectiveness.To evaluate the efficacy and safety of treatment randomized trial.From August 2015 to July 2017, multicenter, placebo-controlled trial was conducted at 13 large- medium-sized hospitals China.A total 360 120 patients were initially enrolled control groups, respectively; 386...
Cadmium (Cd), a ubiquitous toxic heavy metal, with the intractable trait of low degradation, can induce multiple organ damage. Whereas, far less is known about its neurotoxicity and specific mechanism in chronic Cd exposure. To investigate Cd2+ , we traced effects for up to 30 months mice which were exposed by drinking mimicking Cd-polluted water. We found toxicity exposure was process associated transition from autophagy apoptosis, switch autophagy-apoptosis dose-dependent threshold [Cd2+ ]...
Immune-enhancing thymosin alpha 1 (Tα1) therapy may reduce infected pancreatic necrosis (IPN) in acute necrotising pancreatitis (ANP). However, the efficacy might be impacted by lymphocyte count due to pharmacological action of Tα1. In this post-hoc analysis, we tested hypothesis that pre-treatment absolute (ALC) determines whether patients with ANP benefit from Tα1 therapy. A analysis data a multicentre, double-blind, randomised, placebo-controlled trial testing predicted severe was...
Objective. To identify significant pathways and genes in intervertebral disc degeneration (IDD) based on bioinformatics analysis. Design. The GEO database was used to download the GSE124272 dataset. Differentially expressed (DEGs) were analyzed using Limma package R language. Then, gene ontologies (GO), Kyoto encyclopedia of genomes (KEGG), protein-protein interaction (PPI) networks further hub genes. mRNA expression levels top six verified. Results. We found 563 DEGs, which 214 upregulated...
Hepatogastric fistula (HGF) is an uncommon occurrence that can be associated with various medical conditions. The primary causes typically involve peptic ulcer disease, infections (such as pyogenic, amoebic or tuberculosis), iatrogenic factors (like post transarterial chemoembolization radiotherapy). Massive gastrointestinal hemorrhage following HGF extremely rare, iodine-125 (
About 55% of hepatocellular carcinoma (HCC) cases in China are advanced HCC at the initial diagnosis. We aimed to evaluate efficacy and safety hepatic arterial infusion chemotherapy (HAIC) for with portal vein tumor thrombosis (PVTT) compared transcatheter chemoembolization (TACE) after propensity score matching (PSM).A score-matched cohort study was performed patients PVTT who underwent either HAIC using oxaliplatin plus raltitrexed or TACE three institutions between January 2016 2021....
The study aimed to assess the safety and efficacy of conversion therapy with portal vein embolization (PVE) transcatheter arterial chemoembolization (TACE) in patients large unresectable hepatocellular carcinoma (HCC) ipsilateral tumor thrombus (PVTT).This retrospective evaluated consecutive initially (≥5 cm) HCC PVTT who underwent PVE + TACE at our center between June 2016 September 2020 (Group A). Clinically equivalent from three centers were receiving tyrosine kinase inhibitors (TKIs) B)...
Percutaneous transhepatic biliary drainage (PTBD) is an effective treatment for benign and malignant obstructive jaundice. Major bleeding complications occur in approximately 2-3% of patients after PTBD, which can result death. A case involving a 63-year-old male with jaundice, who experienced severe reported. Emergency digital subtraction angiography, celiac trunk artery superior mesenteric angiography were performed; however, no signs arterial found. To identify etiology, portal venography...
In order to solve the problem of observation blind area on outer end face cigarette groove filter centering drum GD121—AF12 assembler, an auxiliary mirror was designed and installed inner wall nearby. According light reflection law, according space position central , design surface support parts refer available screw holes center wall, calculate relative deflection angle parts. Based above data, are with Pro/E, made 3D printer. After improved equipment is blocked, manual cleaning time...
Objective To discuss the feasibility of biodegradable covered magnesium alloys stent for a rabbit model lateral aneurysm in common carotid artery (CCA). Methods The left CCA was ligated 20 conventional New Zealand rabbits. MRA neck performed 1 month after ligation. The rabbits with thickening right and non- or slight bilateral vertebral arteries were selected making. venous pouch wall by discontinuous extroversion sutures, to form model. stents Willis inserted two weeks Angiography...
Objective To explore the clinical value of percutaneous osteoplasty (POP) with and without interventional internal fixation (IIF) on malignant impending pathological fracture proximal femur. Methods In this retrospective study, a total 40 patients femur were recruited for POP IIF (n=19) or alone (n=21). Pain relief,fracture,bone cement leakage survival was observed after treatment, which difference between two groups compared by Chi-square test. visual analog scale(VAS),karnofsky...
The objective of this study was to investigate the method, efficacy, and safety endovascular treatment (EVT) delayed splenic artery branch (SAB) hemorrhage after pancreaticoduodenectomy.From March 2019 January 2022, all patients underwent EVT SAB for post-pancreaticoduodenectomy were included. Demographic, laboratory, angiographic, clinical follow-up data collected analyzed.A total eight enrolled. In two patients, celiac axis angiography alone failed, but selective (SA) demonstrated...