A5063769184- Organ Transplantation Techniques and Outcomes
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Hepatitis C virus research
- Retinoids in leukemia and cellular processes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal Transplantation Outcomes and Treatments
- Pancreatic and Hepatic Oncology Research
- Vascular Procedures and Complications
- Case Reports on Hematomas
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Peripheral Artery Disease Management
- Electrolyte and hormonal disorders
- Liver physiology and pathology
- Gallbladder and Bile Duct Disorders
- NF-κB Signaling Pathways
- Entomological Studies and Ecology
- Hepatitis Viruses Studies and Epidemiology
- Dermatologic Treatments and Research
- Genomics, phytochemicals, and oxidative stress
- Anesthesia and Pain Management
- Neurological and metabolic disorders
Chonnam National University Hospital
2019-2023
Konkuk University
2012-2023
Gyeongsang National University Hospital
2007-2020
Chonnam National University Hwasun Hospital
2018
Konkuk University Medical Center
2008-2015
Santa Clara County Behavioral Health Services
2014
Gyeongsang National University
2007-2011
Doheny Eye Institute
2010
Virginia Commonwealth University Medical Center
2004-2005
University Malaya Medical Centre
2001-2004
Postlaparoscopic shoulder pain (PLSP) frequently follows laparoscopic surgery. In this placebo-controlled study, we evaluated the efficacy of two perioperative doses pregabalin 300 mg 12 h apart for preventing and attenuating PLSP after cholecystectomy. The frequency severity PLSP, need postoperative rescue analgesia, side effect profiles were assessed 48 postoperatively. both groups, overall incidence did not differ significantly, score time to first cumulative ketorolac consumption similar...
Tetraarsenic hexoxide (As4O6) has been used in Korean folk medicines for the treatment of cancer, however its anti-cancer mechanisms remain obscured. Here, this study investigated effect As4O6 on SW620 human colon cancer cells. showed a dose-dependent inhibition cells proliferation. significantly increased sub-G1 and G2/M phase population, Annexin V-positive manner. arrest was concomitant with augment p21 reduction cyclin B1, cell division cycle 2 (cdc 2) expressions. Nuclear condensation,...
Genetic alterations of TERT and CTNNB1 have been documented in hepatocellular carcinoma. promoter mutations are the earliest genetic events multistep process hepatocarcinogenesis related to cirrhosis. However, analyses carcinoma tumor samples not performed Korean population, where hepatitis B virus-related is prevalent. In order identify role pathogenesis recurrent carcinoma, we sequence 140 nodules (including 107 carcinomas), 8 pairs matched primary relapsed carcinomas. were only observed...
Background: The extract of Allium cepa Linn is commonly used as adjuvant food for cancer therapy.We assumed that it includes a potential source anti-cancer properties.Methods: We investigated effects polyphenols extracted from lyophilized A. (PEAL) in AGS human cells.Results: PEAL inhibited cell growth dose-dependent manner.It was related to caspase-dependent apoptosis.We confirmed this finding with annexin V staining.PEAL up-regulated p53 expression, and subsequent Bax induction, down...
Objective:We wanted to evaluate the status of self-expandable nitinol stents implanted in P2 and P3 segments popliteal artery Korean patients. Materials Methods:We retrospectively analyzed 189 consecutive patients who underwent endovascular treatment for stenoocclusive lesions femoropopliteal from July 2003 March 2009, 18 stent placement arterial were fi nally enrolled.Lesion patency was evaluated by ultrasound or CT angiography, fracture assessed plain X-rays at 1, 3, 6 12 months annually...
Evidence suggests that auranofin (AF) exhibits anticancer activity by inhibiting thioredoxin reductase (TrxR). Here, in this study, we have investigated the synergistic effects of AF and morin their mechanism for focusing on apoptosis Hep3B human hepatocellular carcinoma cells. We assessed activities annexin V/PI double staining, caspase, TrxR assay. Morin enhances inhibitory as well reducing cell viability. Annexin staining revealed morin/AF cotreatment induced apoptotic death. AF‐induced...
We previously demonstrated that anthocyanins from the fruits of Vitis coignetiae Pulliat (AIMs) induced apoptosis hepatocellular carcinoma cells. However, many researchers argued concentrations AIMs were too high for in vivo experiments. Therefore, we performed vitro at lower and experiments anti-cancer effects AIMs. inhibited cell proliferation Hep3B cells a dose-dependent manner with maximum concentration 100 µg/mL. also invasion migration µg/mL or without presence TNF-α. To establish...
The frequency of isoniazid hepatotoxicity is low in children receiving therapy for latent tuberculosis infection. However, may cause liver failure and death. We evaluated who developed to determine demographic clinical characteristics.A retrospective review was performed medical records 1582 patients aged <18 years were at a public health department clinic California.There 13 had infection (0.8% all started isoniazid; 1.1% 1235 completed the 9-month therapy). There 8 girls (62%) 9 Hispanic...
Anthocyanins isolated from Vitis coignetiae Pulliat (Meoru in Korea) (AIMs) have various anti-cancer properties by inhibiting Akt and NF-κB which are involved drug resistance. Cisplatin (CDDP) is one of the popular agents. Studies reported that MCF-7 human breast cancer cells high resistance to CDDP compared other cell lines. In this study, we confirmed tested whether AIMs can overcome cells. Cell viability assay revealed were more resistant treatment than MDA-MB-231 exhibiting aggressive...
Background Diabetes mellitus tends to have the greatest impact on smaller vessels and contributes significantly occlusive disease from popliteal artery distally. Purpose To evaluate clinical outcomes after a balloon angioplasty with or without stent placement in diabetic patients critical limb ischemia (CLI) by chronic total occlusion (CTO) limited below-the-knee (BTK) arteries. Material Methods From August 2005, who presented CLI CTO BTK arteries, underwent endovascular treatment, were...
The shortage of donor organs occasionally mandates the use hepatic allografts from anti-HBc (+) donors. HBIG and/or lamivudine are recommended for prevention de novo HBV infection in naive patients, but there attendant problems, such as mutant strain emergence and high cost. Active immunization presents a better alternative than or lamivudine, if it can be proven to effective. Accordingly, we investigated outcome vaccination pediatric transplant recipients. Between July 1999 October 2001, 19...
Abstract: Liver recipients who have antibodies to hepatitis B core antigen (anti‐HBc) or received an anti‐HBc positive liver graft are at risk of acquiring de novo infection so a life long prophylaxis is required. A post‐transplant vaccination against virus (HBV) can offer better alternative than either hyperimmune globulin (HBIG) lamivudine. This study investigated the course anti‐HBs titer after and analyzed factors that influence response. Between October 1999 February 2003, 37 pediatric...
Cisplatin (cis-diaminedichloroplatinum, CDDP) is a widely used chemotherapeutic agent for the treatment of many cancers. However, initial resistance to CDDP serious problem in treating these Vitis coignetiae Pulliat (Meoru Korea) have shown anti-nuclear factor kappa B and anti-epidermal growth receptor activities cancer cells.In this study, order seeking an approach increase anti-cancer effects with natural products. Here, we investigated anthocyanins isolated from (anthocyanidins meoru,...
A fecaloma refers to a mass of accumulated feces that is much harder than associated with fecal impaction. Fecalomas are usually found in the rectosigmoid area. 10-year-old male chronic constipation was admitted because increasing abdominal pain. An computed tomography scan and simple x-ray revealed rapidly evolving mechanical obstruction small intestine. Most fecalomas successfully treated by conservative methods such as laxatives, enemas rectal evacuation. When treatments have failed,...
What is known and objective Febuxostat now recommended as the first-line pharmacological urate-lowering therapy for gout in American College of Rheumatology guidelines. There no case rhabdomyolysis associated with febuxostat among reported side effects drug. Our to report on a initiation patient chronic kidney disease (CKD). Case summary A 73-year-old male visited our emergency room due progressive weakness both lower extremities starting 3 days earlier. Ten before presentation, his primary...
To evaluate the technical feasibility and preliminary results of endovenous foam sclerotherapy using a microcatheter in varicose tributaries followed by laser treatment (EVLT) incompetent saphenous veins.From July 2005 to August 2006, 312 patients (M:F=139:173, mean age 45.8) who presented with veins reflux saphenofemoral, saphenopopliteal junction or were enrolled. Under ultrasound fluoroscopy guidance, selective microcatheterization slcerotherapy first performed tributaries, EVLT (980 nm)...
Percutaneous ablation of incompetent perforators has been introduced as a safe and efficacious alternative.To compare two methods treating thigh perforator great saphenous veins (GSV).Patients with varicose CEAP C2 C3 perforating (IPVs) in the without evidence saphenofemoral reflux obvious venous from IPVs into GSV distal to were included. Endovenous laser was done using (IPV (IPVA) versus ablation: GSVA). Their technical success rate, clinical complications compared at 1 week, 1, 3, 6, 12...