A5101968865- Organ Transplantation Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Liver physiology and pathology
- Pancreatitis Pathology and Treatment
- Cancer Mechanisms and Therapy
- Radiomics and Machine Learning in Medical Imaging
- Abdominal Trauma and Injuries
- Organ Donation and Transplantation
- Congenital Anomalies and Fetal Surgery
- Cancer-related molecular mechanisms research
- Cancer, Hypoxia, and Metabolism
- Hepatitis B Virus Studies
- Cancer, Lipids, and Metabolism
- Biological and pharmacological studies of plants
- GABA and Rice Research
- Plant Molecular Biology Research
- Transplantation: Methods and Outcomes
- Cancer Research and Treatments
- Biliary and Gastrointestinal Fistulas
Beijing Tsinghua Chang Gung Hospital
2016-2025
Tsinghua University
2016-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2025
Tangshan College
2025
Chinese Academy of Engineering
2025
Second Hospital of Shandong University
2022-2025
Beijing Tongren Hospital
2025
Capital Medical University
2025
Ministry of Industry and Information Technology
2025
Nanjing University of Science and Technology
2025
<b><i>Background:</i></b> Primary liver cancer, around 90% are hepatocellular carcinoma in China, is the fourth most common malignancy and second leading cause of tumor-related death, thereby posing a significant threat to life health Chinese people. <b><i>Summary:</i></b> Since publication <i>Guidelines for Diagnosis Treatment Liver Cancer (2017 Edition)</i> 2018, additional high-quality evidence has emerged with relevance...
The sudden outbreak of novel coronavirus 2019 (COVID-19) increased the diagnostic burden radiologists. In time an epidemic crisis, we hoped artificial intelligence (AI) to help reduce physician workload in regions with outbreak, and improve diagnosis accuracy for physicians before they could acquire enough experience new disease. Here, present our building deploying AI system that automatically analyzes CT images detect COVID-19 pneumonia features. Different from conventional medical AI,...
Unlike hematological malignancies, solid tumors have proved to be less susceptible chimeric antigen receptor (CAR)-T cell therapy, which is partially caused by reduced accumulation of therapeutic T cells in tumor site. Since efficient trafficking the precondition and pivotal step for infused CAR-T exhibit their anti-tumor function, strategies are highly needed improve ability treatment. Here, based on natural lymphocyte chemotaxis theory characteristics microenvironments, we explored...
Nagino, Masato MD; DeMatteo, Ronald Lang, Hauke Cherqui, Daniel Malago, Massimo Kawakatsu, Shoji DeOliveira, Michelle L. Adam, René Aldrighetti, Luca Boudjema, Karim Chapman, William Clary, Bryan de Santibañes, Eduardo Dong, Jiahong Ebata, Tomoki Endo, Itaru Geller, David Guglielmi, Alfredo Kato, Tomoaki Lee, Sung-Gyu Lodge, Peter Nadalin, Silvio Pinna, Antonio Polak, Wojciech Soubrane, Olivier Clavien, Pierre-Alain MDAuthor Information
To assess the feasibility and safety of robotic-assisted laparoscopic anatomic hepatectomy.The development minimally invasive surgery has led to an increase in use hepatectomy. However, hepatectomy remains technically challenging is not widely developed. Robotic represents a recent evolution that being used increasingly for complex surgical procedures. Herein, we report our initial experience with 13 consecutive patients.Between April July 2009, patients underwent hepatectomies benign...
To analyze the risk factors for pancreatic fistula after pancreaticoduodenectomy.
Detection of hepatocellular carcinoma circulating tumor cells performed with conventional strategies, is significantly limited due to inherently heterogeneous and dynamic expression EpCAM, as well degradation cytokeratins during epithelial-to-mesenchymal transition, which inevitably lead non-negligible false negative detection such "uncapturable invisible" CTCs. A novel SE-iFISH strategy, improved for HCC CTCs in this study, was applied comprehensively detect, situ phenotypically...
Portal vein tumor thrombus (PVTT) is very common and it plays a major role in the prognosis clinical staging of hepatocellular carcinoma (HCC). We have published first version guideline 2016 revised 2018. Over past several years, many new evidences for treatment PVTT become available, especially advent targeted drugs immune checkpoint inhibitors which further improved PVTT. So, Chinese Association Liver Cancer Medical Doctor 2018 to adapt development treatment. Future strategies HCC with...
Intracellular lipid accumulation is commonly seen in fibrotic livers, but its exact role liver fibrosis remains elusive. Here, we established a multimodal nonlinear optical microscopy to quantitatively map distribution of biomolecules livers. Our data revealed that unsaturated triglycerides were predominantly accumulated central vein area during not portal area. Moreover, the homeostasis was remarkably dysregulated late-stage compared early-stage fibrosis, including increased with decreased...
The role of autotransplantation in end-stage hepatic alveolar echinococcosis (AE) is unclear. We aimed to present our 15-case experience and propose selection criteria for autotransplantation. All patients were considered have unresectable AE by conventional resection due critical invasion retrohepatic vena cava, hepatocaval region along with three veins, the tertiary portal arterial branches. successfully underwent ex vivo extended right hepatectomy without intraoperative mortality. median...
To establish a scoring system to predict clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreaticoduodenectomy (PD).The clinical records of 921 consecutive patients who underwent PD between 2008 and 2013 were reviewed retrospectively. Postoperative (POPF) was defined classified by the international study group (ISGPF). We used logistic regression model determine independent risk factors CR-POPF developed based on coefficient model. The optimal cut-off value divide...
Clinically significant portal hypertension (CSPH) is associated with an incremental risk of esophageal varices and overt clinical decompensations. However, hepatic venous pressure gradient (HVPG) measurement, the gold standard for defining CSPH (HVPG≥10 mm Hg) invasive therefore not suitable routine practice. This study aims to develop validate a radiomics-based model as noninvasive method accurate detection in cirrhosis.The prospective multicenter diagnostic trial (CHESS1701,...
Objective: To test the degree of agreement in selecting therapeutic options for patients suffering from colorectal liver metastasis (CRLM) among surgical experts around globe. Summary/Background: Only few areas medicine have seen so many novel over past decades as tumors. Significant variations may therefore exist regarding choices treatment, even experts, which confuse both medical community and patients. Methods: Ten cases CRLM with different levels complexity were presented to 43 expert...