A5068546978- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Thyroid Cancer Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Peptidase Inhibition and Analysis
- RNA modifications and cancer
- Tracheal and airway disorders
- Lung Cancer Treatments and Mutations
- Urological Disorders and Treatments
- Cancer-related gene regulation
- Neuroendocrine Tumor Research Advances
- Per- and polyfluoroalkyl substances research
- Genetic factors in colorectal cancer
- Medical Imaging and Pathology Studies
- Cancer, Hypoxia, and Metabolism
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Advanced Biosensing Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Ferroptosis and cancer prognosis
- DNA Repair Mechanisms
- Microbial Community Ecology and Physiology
- Tea Polyphenols and Effects
Chengdu University of Technology
2024-2025
Soochow University
2024
First Affiliated Hospital of Soochow University
2024
Zhejiang University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2018-2024
Chongqing Medical University
2018-2024
First Affiliated Hospital Zhejiang University
2023-2024
Huzhou University
2024
Shanghai Ocean University
2023
Pudong New Area People's Hospital
2021-2023
Porosity is considered to be one of the key factors affecting structural properties porous lattices, but in fact, pore size also plays an important role, and it has great potential adjust porosity independently improve properties. In this work, by adjusting sheet thickness triply periodic minimal surface (TPMS) lattice structures height single row structure according linear constant laws, TPMS with given adjustable are designed, mechanical response investigated. Based on preparing samples...
Radioresistance is the major reason for failure of radiotherapy in esophageal squamous cell carcinoma (ESCC). Previous evidence indicated that stanniocalcin 2 (STC2) participates various biological processes malignant tumors. However, researches on its effect radioresistance cancers are limited. In this study, STC2 was screened out by RNA-sequencing and bioinformatics analyses as a potential prognosis predictor ESCC radiosensitivity then determined to facilitate radioresistance. We found...
Objectives: To develop reliable nomograms to estimate individualized overall survival (OS) and cancer specific (CSS) for patients with primary small cell carcinoma of the bladder (SCCB) compare predictive value AJCC stages. Patients Methods: 582 eligible SCCB identified in Surveillance, Epidemiology, End Results (SEER) dataset were randomly divided into training (n=482) validation (n=100) cohorts. Akaike information criterion was used select clinically important variables multivariate Cox...
Background: We aimed to evaluate the prognostic value of site-specific metastases in patients with metastatic bladder cancer and analyze roles that surgeries play treatment this malignancy. Materials methods: A population-based retrospective study using Surveillance, Epidemiology End Results dataset was performed were classified according sites (bone, brain, liver, lung distant lymph nodes). Kaplan–Meier analysis log-rank test used for survival comparisons. Multivariate Cox regression model...
Mutations of BRAFV600E and TERT promoters are associated with thyroid cancer development. This study further investigated association these mutations clinicopathological characteristics from patients papillary carcinoma (PTC).Tumor tissues 342 PTC were obtained for DNA extraction polymerase chain reaction amplification to detect the mutation using amplification-refractory system-polymerase reaction. promoter assessed Sanger sequencing. The gene was then statistically analyzed.Two hundred...
By comparing the detection rate and type of targeted gene mutations in non-small cell lung cancer (NSCLC) between amplification refractory mutation system PCR (ARMS-PCR) next-generation sequencing (NGS), characteristics application advantages are explained, providing a basis for clinicians to effectively select corresponding methods.The cases genes were selected from First Affiliated Hospital Chongqing Medical University January 2016 October 2020. A sample 4467 was selected, they diagnosed...
Abstract Due to the deficiency of mechanical supporting after discectomy and weak proliferative capacity annulus fibrosus (AF) cells, AF defect repair remains a clinical challenge. Herein, myofibroblasts derived extracellular vesicles (M‐EVs) functional “brick‐cement” bio‐integrated system (M‐EVs@PGBgel) is developed defect. The modified Poly(glycerol‐sebacate) (PGBS), “bio‐brick” layer, exhibited excellent support features on account its elastomeric properties. loaded M‐EVs in “bio‐cement”...
Abstract Suspension bath‐based 3D bioprinting (SUB3BP) is effective in creating engineered vascular structures. The transfer of oxygen and nutrients via networks necessary for tissue or organ survival integration following transplantation. Existing SUB3BP techniques face challenges fabricating hierarchical structures with multicellular organization, including issues related to suspension bath removal, restricted material choices, low accuracy. A next‐generation technique that removal‐free...
Microsatellite instability (MSI) is one of the most important molecular characteristics colorectal cancer (CRC), which mainly results from defective DNA mismatch repair (MMR). This study was performed to investigate concordance between deficient MMR and MSI testing, evaluate association these two with clinicopathological in Chinese CRC patients.A total 738 patients were included. Tumor tissues paired peripheral blood specimens obtained. Screening for investigated using immunohistochemical...
Fibronectin (FN) is associated with tumorigenesis and progression in bladder cancer, however, the underlying mechanisms causing this remain largely unknown. Furthermore, cancerous inhibitor of protein phosphatase 2A (CIP2A) has been shown to play important regulatory roles cancer proliferation. Here, we investigated whether FN regulates CIP2A expression promote cell The correlations stromal proliferating nuclear antigen (PCNA) were analyzed a cohort patients. regulating proliferation...
To assess the predictability value of Sarcopenia index((SI, serum creatinine value/cystatin C value×100) in determining potential chemotherapy-induced undesirable reactions and eventual death older patients diagnosed with stage III or IV non-small cell lung cancer (NSCLC). General information was retrieved from health records mortality data obtained by phone interview. Serum Cr CysC levels were measured before chemotherapy. The endpoints recorded any causes. Logit regression analysis...
Effective characterization of protein biomarkers status on the cell surface has important value in diagnosis and treatment diseases.Traditional immunohistochemistry can only assess expression level rather than accurately reflect their interaction oligomerization, resulting inevitable problems for personalized therapy.Methods: Herein, we developed a novel DNAzyme-catalyzed tyramide depositing reaction (DCTDR) situ amplified imaging membrane status.By using human epidermal growth factor...
Purpose: This study aimed to compare perioperative outcomes of open partial nephrectomy (OPN) and laparoscopic (LPN) from a retrospective single-center dataset. Patients Methods: A analysis 210 patients who underwent (n=91) or (n =119) for RCC was conducted between 2012 2015. All were grouped into low complexity, moderate high complexity according the R.E.N.A.L. Nephrometry Score, respectively. The rates intraoperative postoperative complications estimated blood loss, warm ischemia time,...
Imatinib plasma trough levels (IM Cmin) have been reported to a considerable clinical impact in patients with gastrointestinal stromal tumors (GISTs). We therefore investigated the factors affecting IM concentration Chinese GIST patients.IM Cmin 190 who were taking measured.In treated 300 mg/day (n = 16), 400 168), and > (500: n 1, 600: 5), was 1,564.54 ± 596.15, 1,521.26 610.33, 2,540.31 1,298.14 ng/mL, respectively. Of 168 mg/day, significantly lower males (1,353.94 492.89 ng/mL) than...
Poor response and chemotherapy resistance to cisplatin (DDP)‑based therapy frequently lead treatment failure in advanced bladder cancer; however the underlying mechanism is extremely complex unclear. Furthermore, cancerous inhibitor of protein phosphatase 2A (CIP2A), a recently identified human oncoprotein, has been shown play important regulatory roles cancer cell survival. The present study aimed investigate correlation CIP2A with sensitivity DDP cells. In study, knockdown was performed...