- Structural Load-Bearing Analysis
- Superconducting Materials and Applications
- Structural Behavior of Reinforced Concrete
- Fire effects on concrete materials
- Colorectal Cancer Surgical Treatments
- Primate Behavior and Ecology
- Physics of Superconductivity and Magnetism
- Memory and Neural Mechanisms
- Colorectal Cancer Treatments and Studies
- Retinal Development and Disorders
- Colorectal and Anal Carcinomas
- Neuroscience and Neuropharmacology Research
- Bacteriophages and microbial interactions
- CRISPR and Genetic Engineering
- Anesthesia and Sedative Agents
- Spacecraft and Cryogenic Technologies
- Management of metastatic bone disease
- HVDC Systems and Fault Protection
- Structural Engineering and Vibration Analysis
- Frequency Control in Power Systems
- Neural dynamics and brain function
- Structural Response to Dynamic Loads
- COVID-19 and healthcare impacts
- Advanced machining processes and optimization
- Skin Protection and Aging
Kyoto University
1997-2024
Nippon Steel (Japan)
2009-2024
Nagoya University
2024
Hyogo University
2023-2024
National Institute for Land and Infrastructure Management
2022
Shizuoka Medical Center
2022
Saga University
2019
Hyogo Medical University
2019
Nippon Steel (Germany)
2018
Gunma University
2017
Recent emphasis has been placed on gene transduction mediated through recombinant adeno-associated virus (AAV) vector to manipulate activity of neurons and their circuitry in the primate brain. In present study, we created a novel which capsid was composed proteins derived from both AAV serotypes 1 2 (AAV1 AAV2). Following injection into frontal cortex macaque monkeys, this mosaic vector, termed AAV2.1 found exhibit excellence transgene expression (for AAV1 vector) neuron specificity AAV2...
Summary Extramedullary myeloma ( EMM ) occurs when develops outside the bone marrow; it often after chemotherapy and is associated with acquisition of chemo‐resistance a fatal course. The mechanisms underlying extramedullary spread have not yet been fully elucidated. MALAT 1 highly abundantly ubiquitously expressed long non‐coding RNA that plays important roles in cancer metastasis. aims this study were to clarify association elucidate mechanism formation under chemotherapeutic pressure....
To interrogate particular neuronal pathways in nonhuman primates under natural and stress-free conditions, we applied designer receptors exclusively activated by drugs (DREADDs) technology to common marmosets. We injected adeno-associated virus vectors expressing the excitatory DREADD hM3Dq into unilateral substantia nigra (SN) four Using multi-tracer positron emission tomography imaging, detected expression vivo, which was confirmed nigrostriatal dopamine neurons immunohistochemistry, as...
AME Aquatic Microbial Ecology Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 73:171-183 (2014) - DOI: https://doi.org/10.3354/ame01713 Temperature alters algicidal activity of DNA and RNA viruses infecting Chaetoceros tenuissimus Y. Tomaru1,*, K. Kimura1,2, H. Yamaguchi3 1National Research Institute Fisheries Environment Inland Sea, Agency, 2-17-5 Maruishi, Hatsukaichi, Hiroshima 739-0452, Japan...
A subcortical pathway through the superior colliculus and pulvinar has been proposed to provide amygdala with rapid but coarse visual information about emotional faces. However, evidence for short-latency, facial expression-discriminating responses from individual neurons is lacking; even if such a response exists, how it might contribute stimulus detection unclear. Also, no definitive anatomical available assumed pathway. Here we showed that ensemble of in monkeys carried robust...
This paper describes results of the R and D on 70 MW class superconducting generators called model machines in an 11-year period project conducted by Super-GM. Three types are under manufacturing now. Static excitation tests two slow response type performed. The test facility is also construction.
The entorhinal cortex (EC) is a major gateway between the hippocampus and telencephalic structures, plays critical role in memory navigation. Through use of various molecular markers genetic tools, neuron types constituting EC are well studied rodents, their layer-dependent distributions, connections, functions have also been characterized. In primates, however, such cell-type-specific understandings lagging. To bridge gap rodents here we provide first cell-type-based global map macaque...
Post-operative biting sensitivity is a significant clinical problem after placement of posterior resin composites and may be due to dentinal fluid movement. The occlusal surfaces extracted teeth were filled with amalgam (control) or various composites, the movement induced by loading restorations was studied. In addition, firing pulpal nerves class 5 composite in canine dogs also investigated. When entire cavity etched an acid gel then composite, response significantly (p less than 0.01)...
Abstract Given their high sociality and close evolutionary distance to humans, monkeys are an essential animal model for unraveling the biological mechanisms underlying human social behavior elucidating pathogenesis of diseases exhibiting abnormal behavior. However, behavioral analysis naturally behaving requires manual counting various behaviors, which has been a bottleneck due problems in throughput objectivity. Here, we developed three-dimensional markerless motion capture system that...
Background and aims – Diatoms are one of the most species rich groups organisms on Earth. They fundamental in supporting biomass natural environment. The presence marine viruses can greatly influence diatom diversity their environment has attracted interest from multi-disciplinary research teams after a infected virus was reported for first time 21st century. As initial this field demonstrated, acquisition new it is important to learn about infect hosts. Therefore, we have been searching...
The radiological diagnosis of Crohn's disease (CD)‑related anorectal cancer is difficult; it often found in advanced stages and has a poor prognosis because the difficulty curative surgery. However, there are no studies on predicting CD‑related cancer. present study aimed to develop predictive model diagnose CD cancerous lesions more accurately way that can be interpreted by clinicians. Patients with who developed at Hyogo Medical University (Nishinomiya, Japan) between March 2009 June 2022...
Recent emphasis has been placed on gene transduction mediated through recombinant adeno-associated virus (AAV) vector to manipulate activity of neurons and their circuitry in the primate brain. In present study, we created a novel AAV which capsid was composed proteins derived from serotypes 1 2 (AAV1 AAV2). Following injection into frontal cortex macaque monkeys, this mosaic vector, termed AAV2.1 found exhibit excellence transgene expression (for AAV1 vector) neuron specificity AAV2...
The objective of this study is to develop weld-free beam-to-column connection for H-SA700A high strength steel members, and verify the structural behavior proposed connections. Knee brace damper friction were used connect beam column by bolts; trigger level these dampers designed remain as elastic. Full-scale testing knee-brace showed that yielded at target all part connections performed expected. Friction damper, which aluminum sprayed surface, obtained 0.7 slip coefficient a stable...
To interrogate particular neuronal pathways in non-human primates under natural and stress-free conditions, we applied designer receptors exclusively activated by drugs (DREADDs) technology to common marmosets. We injected adeno-associated virus vectors expressing the excitatory DREADD hM3Dq into unilateral substantia nigra three Using multi-tracer positron emission tomography imaging, detected expression vivo, which was confirmed nigrostriatal dopamine neurons immunohisto-chemistry,...
A national project to develop a superconducting generator was begun in 1988 Japan under the New Sunshine Project of AIST, MITI. This has merits higher efficiency and compactness for transmission lines. 70 MW class is goal project. The authors have been developing rotor having field winding stator an air-gap armature winding. designed be cryostable so as recover from partial transition normal conduction. tested nonrotating cryostat, excitation performance stability were confirmed enough...
HcRNAV is a small icosahedral virus that infects the shellfish-killing marine dinoflagellate Heterocapsa circularisquama, which harbors dicistronic linear single-stranded RNA (ssRNA) genome ca. 4.4 kb in length. Its major capsid protein (MCP) gene sequence not expressed by various strains of Escherichia coli, possibly because codon usage problem. To solve this problem, chemically modified (i.e., de novo synthesized) was designed and cloned into pCold-GST expression vector, transformed E....