A5100463035- Analytical Chemistry and Chromatography
- Plant chemical constituents analysis
- Chromatography in Natural Products
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Molecular Biology Techniques and Applications
- Phytochemical compounds biological activities
- Plant biochemistry and biosynthesis
- Genetic diversity and population structure
- Plant tissue culture and regeneration
- Plant Gene Expression Analysis
- Genomics and Phylogenetic Studies
- Chromosomal and Genetic Variations
- vaccines and immunoinformatics approaches
- Genomic variations and chromosomal abnormalities
- Natural product bioactivities and synthesis
- Lipid metabolism and biosynthesis
- Plant and Fungal Species Descriptions
- Pneumonia and Respiratory Infections
- Forest, Soil, and Plant Ecology in China
- RNA and protein synthesis mechanisms
- Magnetic and Electromagnetic Effects
- Insect and Arachnid Ecology and Behavior
- Cancer-related molecular mechanisms research
Second Affiliated Hospital of Fujian Medical University
2019-2025
Fujian Medical University
2019-2025
People's Hospital of Xinjiang Uygur Autonomous Region
2024-2025
Henan Agricultural University
2024
Anhui Agricultural University
2024
South China Agricultural University
2011-2022
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2018-2021
Beijing Forestry University
2004-2020
Tsinghua University
2020
Key Laboratory of Guangdong Province
2019
Streptococcus gallolyticus is a non-motile, gram-positive bacterium that causes infective endocarditis. S. has developed resistance to existing antibiotics, and no vaccine currently available. Therefore, it essential develop an effective vaccine. Core proteomics was used in this study together with subtractive reverse vaccinology approach find antigenic proteins could be utilized for the design of multi-epitope The pipeline identified two as potential targets: penicillin-binding protein ATP...
The HD-Zip transcription factors play a crucial role in plant development, secondary metabolism, and abiotic stress responses, but little is known about I genes soybean. Here, homeodomain-leucine zipper gene designated GmHdz4 was isolated. Chimeric soybean plants, overexpressing ( GmHdz4-oe ), gene-editing via CRISPR/Cas9 gmhdz4 ) hairy roots, were generated to examine the response polyethylene glycol (PEG)-simulated drought stress. Bioinformatic analysis showed belonged clade δ, closely...
Abstract Background The Chinese pine ( Pinus tabuliformis ) is an indigenous conifer species in northern China but relatively underdeveloped as a genomic resource; thus, limiting gene discovery and breeding. Large-scale transcriptome data were obtained using next-generation sequencing platform to compensate for the lack of P. information. Results increasing amount on provides excellent resource multi-gene phylogenetic analysis studies how conserved genes functions are maintained face...
Gene regulatory elements, including promoters, enhancers, silencers, etc., control transcriptional programs in a spatiotemporal manner. Though these elements are known to be able induce either positive or negative control, the community has been mostly studying enhancers which amplify transcription initiation, with less emphasis given silencers repress gene expression. To facilitate study of and investigation their potential roles we developed SilencerDB...
Abstract Streptococcus gallolyticus (Sg) is a non-motile, gram-positive bacterium that causes infective endocarditis (inflammation of the heart lining). Because Sg has gained resistance to existing antibiotics and there currently no drug available, developing effective anti-Sg drugs critical. This study combined core proteomics with subtractive technique identify potential therapeutic targets for Sg. Several bioinformatics approaches were used eliminate non-essential human-specific...
In recent years, various mulberry leaf dishes have gradually gained in popularity. The harvesting period of leaves and the preparation dried samples are critical for retention flavonoid content activity. this study, changes levels during their growth (3–6 months), effects four different drying methods [sun (SD), air (AD), oven (OD), freeze (FD)] on accumulation antioxidant capacity were determined. results showed that grown 6 months had higher flavonoids, could significantly affect leaves....
Introduction Endocarditis is a life-threatening infection of the heart valves, frequently caused by pathogenic bacteria. The growth multidrug-resistant bacteria necessitates development innovative therapeutic techniques, such as vaccines. Methods current study employed core proteome analysis and computational-based reverse vaccinology approach across multiple bacterial pathogens associated with endocarditis to identify prospective universal vaccine candidates. contained 121 highly strains...
Jatropha curcas L. seeds an oilseed plant with great potential for biodiesel production. However, low seed yield, which was limited by its lower female flowers, a major drawback utilization. Our previous study found that the flower number and female-to-male ratio were increased gibberellin treatment. Here, we compared transcriptomic profiles of inflorescence meristem at different time points after gibberellic acid A3 (GA3) The present showed 951 differentially expressed genes obtained in...
Abstract The WRKY gene family is an ancient plant transcription factor (TF) with a vital role in growth and development, especially response to biotic abiotic stresses. Although many researchers have studied TFs numerous species, little known of them Tartary buckwheat ( Fagopyrum tataricum ). Based on the recently reported genome sequence buckwheat, we identified 78 FtWRKY proteins that could be classified into three major groups. All 77 genes were distributed unevenly across all eight...
Background: The rapid outbreak of coronavirus disease 2019 (COVID-19) posed a serious threat to China, followed by compulsive measures taken against the national emergency control its further spread. This study was designed describe residents' knowledge, attitudes, and practice behaviors (KAP) during COVID-19. Methods: An anonymous online questionnaire randomly administrated residents in mainland China between Mar 7 16, 2020. Residents' responses KAP were quantified descriptive stratified...
Toona ciliata (Meliaceae) is a rare, fast-growing commercial tree species that produces red timber with beautiful grains. It used to be widely distributed in the past, but few natural forests exist field now. Here, we tested 12 nuclear microsatellite markers derived from 551 individuals of 29 populations China, and investigated genetic diversity population structure T. ciliata. Our results revealed 146 alleles obtained all studied here, an average polymorphic information content 0.723. The...
Abstract Many previous studies have focused on the foraging behaviors and strategies of red imported fire ants, Solenopsis invicta Buren solid food or granular bait; little attention has been paid to how liquid sugar is fed upon. In present study, behavioral responses S. 25% sucrose water droplets were observed. Five patterns identified in colonies under laboratory conditions: (i) no feeding, feeding was observed; (ii) surround ants surrounded along edge droplet; (iii) stacked (iv)...
Zanthoxylum armatum (Z. armatum) is a highly economically important tree that presents special numbing taste. However, the underlying regulatory mechanism of taste remains poorly understood. Thus, elucidation key genes associated with biosynthesis pathways critical for providing genetic information on Z. armatumand breeding high-quality germplasms this species.Here, de novo transcriptome assembly was performed five major organs armatum, including roots, stems, leaf buds, mature leaves and...
Machilus pauhoi Kanehira is an important timber species in China. A provenance trial was recently set up to evaluate the growth performance of trees from different localities, with aim designing seed transfer guidelines. Here, we tested twelve nuclear microsatellite markers derived other Lauraceae family and investigated population genetic structure M. pauhoi. Both number observed alleles per locus (Na) polymorphic information content (PIC) significantly decreased against latitude, but...
ABSTRACT S-palmitoylation is an important reversible protein post-translational modification in organisms. However, its role fungi uncertain. Here, we found the treatment of rice false fungus Ustilaginoidea virens with inhibitor 2 BP resulted a significant decrease fungal virulence. Comprehensive identification sites and proteins U. revealed total 4,089 identified among 2,192 that S-palmitoylated were involved diverse biological processes. Among five palmitoyltransferases, UvPfa3 UvPfa4 to...
Abstract Copy-number-variable (CNV) loci differ from single nucleotide polymorphic (SNP) sites in size, mutation rate, and mechanisms of maintenance natural populations. It is therefore hypothesized that population genetic divergence at CNV will found SNP sites. Here, we test this hypothesis by analysing 856 the genomes 1184 healthy individuals 11 HapMap populations with a wide range ancestry. The results show generally more than three times lower genome-wide Populations exhibit very small (...
Obstructive sleep apnea (OSA) is associated with increased cancer mortality, but the underlying mechanism remains poorly understood. MicroRNAs (miRNAs) are confirmed to be involved in tumorigenesis and tumor progression. However, whether miRNAs have any differential expressions OSA population needs elucidated. The aim of this experimental study was determine alterations various xenograft mice exposed chronic intermittent hypoxia (IH) which considered a hallmark OSA.Sequencing applied screen...