Francesca Di Biasio
A5057627623- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Genetic Neurodegenerative Diseases
- Cerebral Palsy and Movement Disorders
- Autism Spectrum Disorder Research
- Transcranial Magnetic Stimulation Studies
- Parkinson's Disease and Spinal Disorders
- Action Observation and Synchronization
- Balance, Gait, and Falls Prevention
- Advanced Neuroimaging Techniques and Applications
- Vestibular and auditory disorders
- Pain Mechanisms and Treatments
- Dysphagia Assessment and Management
- Nerve Injury and Rehabilitation
- Neural and Behavioral Psychology Studies
- Neuroscience and Neural Engineering
- Functional Brain Connectivity Studies
- Neuroscience and Music Perception
- Stroke Rehabilitation and Recovery
- Neural dynamics and brain function
- Microtubule and mitosis dynamics
- Ion channel regulation and function
- Restless Legs Syndrome Research
- Genetics and Neurodevelopmental Disorders
Ospedale Policlinico San Martino
2018-2025
University of Genoa
2018
Istituto Neurologico Mediterraneo
2011-2017
Sapienza University of Rome
2011-2016
Freezing of gait (FoG) is among the most disabling symptoms Parkinson’s disease (PD) patients. Recent studies showed that action observation training (AOT) with repetitive practice observed actions represents a strategy to induce longer-lasting effects compared standard physiotherapy. We investigated whether AOT may improve FoG and mobility in PD, when applied group-based setting. Sixty-four participants PD were assigned experimental (AO) or control groups underwent 45-minute session, twice...
Abstract Background Tremor disorders remain as clinical diagnoses and the rate of misdiagnosis between commonest non‐parkinsonian tremors is relatively high. Objectives To compare features Essential without other (pure ET), ET plus soft dystonic signs (ET + DS), tremor combined with dystonia (TwD). Methods We compared patients pure ET, DS, TwD enrolled in The ITAlian Network (TITAN). Linear regression models were performed to determine factors associated health status quality life. Results...
Abstract Introduction The recently released classification has revised the nosology of tremor, defining essential tremor (ET) as a syndrome and fueling an enlightened debate about some newly conceptualized entities such ET-plus. As result, precise information demographics, clinical features, natural history these conditions are lacking. Methods ITAlian Network (TITAN) is multicenter data collection platform, aim which to prospectively assess, according standardized protocol, phenomenology...
ABSTRACT Background Postural instability and gait difficulties are key symptoms of Parkinson's disease (PD), elevating the risk falls substantially. Falls afflict 35% to 90% PD patients, representing a major challenge in managing condition. Accurate prediction fall identification contributing factors essential for timely interventions. Objectives Our objective was develop validate machine learning (ML) algorithm across multiple centers Italy accurately forecast identify related using...
Background and purpose Somatosensory t emporal d iscrimination hreshold ( STDT ) is defined as the threshold at which two tactile stimuli applied to skin are perceived clearly distinct. The aim of study was investigate whether extent alterations differs between patients with parkinsonian type m ultiple s ystem a trophy MSA ‐P) P arkinson's isease PD ). Possible differences groups may help differentiate ‐ from . Methods investigated in 20 , 21 18 age‐matched healthy subjects. clinical...
Background Several earlier studies showed a female predominance in idiopathic adult-onset dystonia (IAOD) affecting the craniocervical area and male preponderance limb dystonia. However, sex-related differences may result from bias inherent to study design. Moreover, information is lacking on whether exist expressing other dystonia-associated features spread. Objective To provide accurate relationship between sex differences, motor phenomenology, natural history of IAOD. Methods Data 1701...
Background The burden of Parkinson Disease (PD) represents a key public health issue and it is essential to develop innovative cost-effective approaches promote sustainable diagnostic therapeutic interventions. In this perspective the adoption P3 (predictive, preventive personalized) medicine approach seems be pivotal. NeuroArtP3 (NET-2018-12366666) four-year multi-site project co-funded by Italian Ministry Health, bringing together clinical computational centers operating in field...
Valence (positive and negative) content (embodied vs non-embodied) characteristics of visual stimuli have been shown to influence motor readiness, as tested with response time paradigms. Both embodiment emotional processing are affected in Parkinson's disease (PD) due basal ganglia dysfunction. Here we aimed investigate, using a two-choice paradigm, readiness when embodied (emotional body language [EBL] facial expressions [FACS]) non-embodied scenes [IAPS]) neutral, happy, fearful content....
By providing a stable and smooth L-dopa plasmatic level, L-dopa/carbidopa intestinal gel reproduces the physiological continuous dopaminergic receptor stimulation in patients with Parkinson disease (PD), it therefore represents suitable tool to investigate role of altered neurotransmission pathophysiology motor sensory abnormalities this condition.We studied 11 advanced PD being treated L-Dopa/carbidopa (LCIG) age-matched healthy subjects. Bradykinesia was measured by kinematic recording...