Jean Sénémaud

ORCID: 0000-0001-5353-6405
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About
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Research Areas
  • Aortic aneurysm repair treatments
  • Aortic Disease and Treatment Approaches
  • Infectious Aortic and Vascular Conditions
  • Cardiac, Anesthesia and Surgical Outcomes
  • Abdominal vascular conditions and treatments
  • Vascular Procedures and Complications
  • Peripheral Artery Disease Management
  • Cell Adhesion Molecules Research
  • Esophageal and GI Pathology
  • Protease and Inhibitor Mechanisms
  • Connective tissue disorders research
  • Liver Disease and Transplantation
  • Renal and Vascular Pathologies
  • Cardiac Valve Diseases and Treatments
  • Angiogenesis and VEGF in Cancer
  • Intracranial Aneurysms: Treatment and Complications
  • Atherosclerosis and Cardiovascular Diseases
  • Transplantation: Methods and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Eosinophilic Esophagitis
  • Renal Transplantation Outcomes and Treatments
  • Radiation Dose and Imaging
  • Hemodynamic Monitoring and Therapy
  • Cardiac Structural Anomalies and Repair
  • Climate Change and Health Impacts

Université Paris-Est Créteil
2019-2025

Laboratoire de Recherche Vasculaire Translationnelle
2020-2025

Hôpitaux Universitaires Henri-Mondor
2016-2025

Centre Hospitalier Universitaire Henri-Mondor
2017-2024

Université Paris Cité
2017-2024

Hôpital Bichat-Claude-Bernard
2019-2024

Inserm
2017-2024

Université Gustave Eiffel
2022-2024

Assistance Publique – Hôpitaux de Paris
2017-2023

Sorbonne Université
2022-2023

Alexandre Nuzzo Kévin Guedj Sonja Curac Claude Hercend Claude Bendavid and 95 more Nathalie Gault Alexy Tran‐Dinh Maxime Ronot Antonino Nicoletti Yoram Bouhnik Yves Castier Olivier Corcos Katell Peoc’h Audrey Payancé Carmen Stéfanescu Xavier Treton Francisca Joly Lore Billiauws A. Hamon Auréline Boitet Céline Lekhal David Deutsch Elsa Oiknin Laura Cohen Gabriel Marcellier Jean Sénémaud Félix Corre Damien Soudan Cosmin Sebastian Voican Jean-Baptiste Leclère Jules Iquilles Lucas Raynaud Luisa Paulatto Manon Haas Mathieu Uzzan Mathilde Cohen Sara Tadbiri Servane Prevot Yves Panís Alice Frontali Simon Msika Lara Kelly Ribeiro Lionel Rebibo Konstantinos Arapis Marion Orville Annie Sibert P. Copin Magaly Zappa Marco Dioguardi Burgio Valérie Vilgrain Caroline Bertin Anne Kerbaol Wassim Allaham Quentin Pellenc Arnaud Roussel Pierre Cerceau Iannis Ben Abdallah Antoine Girault Pierre Mordant Romain de Blic Cathérine Paugam‐Burtz Emmanuel Weiss Paër-Sélim Abback I. Enriquez Sylvie Janny Hélène Bout Mikhaël Giabicani Marina Achouf Bénédicte Grigoresco Linda Koy Ear Sonja Curac Agnès Cachier Aurélie Plessier Pierre‐Emmanuel Rautou Dominique Valla Audrey Payancé Alain Sauvanet Safi Dokmak F. Dondéro Ailton Sepulveda Olivier Farges B. Aussilhou Bénédicte Jaïs Dominique Cazals‐Hatem Emmanuelle de Raucourt Larbi Boudaoud Catherine Trichet Hervé Puy Nathalie Pons‐Kerjean Jeanick Stocco J. Bataille Valérie Bouton Philippe Montravers Pascal Augustin Brice Lortat Jacob Jean-Baptiste Michel Dominique Gauguier Marc‐Emmanuel Dumas François Brial Antonis Myridakis

Abstract Early diagnosis of acute mesenteric ischemia (AMI) remains a clinical challenge, and no biomarker has been consistently validated. We aimed to assess the accuracy three promising circulating biomarkers for diagnosing AMI—citrulline, intestinal fatty acid-binding protein (I-FABP), d -lactate. A cross-sectional diagnostic study enrolled AMI patients admitted stroke center controls with abdominal pain another origin. included 129 patients—50 79 controls. Plasma citrulline...

10.1038/s41598-021-98012-w article EN cc-by Scientific Reports 2021-09-23

Background Data on the prognostic impact of type A aortic dissection involving common carotid arteries (CCAs) are scarce. Methods status CCAs were available in 1106 patients who underwent surgery for acute DeBakey 1 recruited a retrospective, multicentre European registry, that is, ERTAAD. Postoperative neurological complications defined as ischaemic stroke, haemorrhagic stroke and/or global brain ischaemia. Results Patients without artery dissection, those with unilateral or bilateral CCA...

10.1136/openhrt-2024-002882 article EN cc-by-nc-nd Open Heart 2025-01-01

IgE type immunoglobulins and their specific effector cells, mast cells (MCs), are associated with abdominal aortic aneurysm (AAA) progression. In parallel, immunoglobulin-producing B organised in tertiary lymphoid organs (TLOs) within the wall, have also been linked to aneurysmal We aimed at investigating potential role mechanism linking local MCs, TLO production progression.Through histological assays conducted on human surgical samples from AAA patients, we uncovered that activated MCs...

10.1371/journal.pone.0295408 article EN cc-by PLoS ONE 2023-12-06

Abstract There is a need for new targets to specifically localize inflammatory foci, usable in wide range of organs. Here, we hypothesized that the cleaved molecular form CD31 suitable target imaging inflammation. We evaluated bioconjugate D-P8RI, synthetic peptide binds all cells with CD31, an experimental rat model sterile acute Male Wistar rats were injected turpentine oil into gastrocnemius muscle two days before 99m Tc-HYNIC-D-P8RI (or its analogue L-Proline) SPECT/CT or [ 18 F]FDG...

10.1038/s41598-019-56163-x article EN cc-by Scientific Reports 2019-12-20

<b><i>Introduction:</i></b> Saccular aneurysms are thought to have a worse prognosis than fusiform in humans, due hemodynamic reasons. However, data comparing and biology saccular lacking. The main objective was evaluate the impact of aneurysm morphology on intra-luminal thrombus (ILT) formation activity. <b><i>Methods:</i></b> Forty Lewis rats were ran­domly divided into 2 groups 20: “saccular” (Group A) “fusiform” B) aneurysms. Decellularized...

10.1159/000506159 article EN Journal of Vascular Research 2020-01-01

Airway complications are frequent after lung transplantation (LT), as they affect up to 23% of recipients. The implication perioperative extracorporeal membrane oxygenation (ECMO) support and haemodynamic instability has never been specifically assessed. first aim this study was explore the impact ECMO on bronchial anastomotic dehiscence (BAD) at Day 90 LT. This prospective observational monocentric analysed BAD in all consecutive patients who underwent LT Bichat Claude Bernard Hospital,...

10.1186/s12890-022-02280-9 article EN cc-by BMC Pulmonary Medicine 2022-12-20

Purpose: The study sought to estimate the prevalence of primary non-aortic lesions (PNAL) unrelated extension aortic dissection (AD) in a cohort patients with Marfan syndrome (MFS). Methods: Adult presenting pathogenic FBN1 mutations and an available pan-aortic contrast-enhanced CTA eight French MFS clinics from April October 2018 were included. Clinical radiological data, particularly presence PNAL (including aneurysm ectasia), retrospectively analyzed. Results: Out 138 patients, 28 (20.3%)...

10.3390/jcm12082902 article EN Journal of Clinical Medicine 2023-04-17

Thymic function decreases progressively with age but may be boosted in certain circumstances. We questioned whether heart transplantation was such a situation and thymic related to the onset of rejection. Twenty-eight antithymocyte globulin-treated transplant recipients were included. Patients diagnosed for an antibody-mediated rejection on endomyocardial biopsy had higher proportion circulating recent emigrant CD4+ T cells cell receptor excision circle levels than other transplanted...

10.1111/ajt.14595 article EN cc-by-nc-nd American Journal of Transplantation 2017-11-21

Background In Marfan syndrome (MFS), an aortic or peripheral arterial dilatation is usually the consequence of dissection. Non-dissecting distal and aneurysms (DAPA) are barely described. We sought to determine incidence prognostic impact non-dissecting DAPA, requiring a surgical repair in large population patients with MFS. Methods The referred French MFS reference center were included prospective database, treated for DAPA between 2013 2020 retrospectively reviewed. first-line therapy was...

10.3389/fcvm.2022.827357 article EN cc-by Frontiers in Cardiovascular Medicine 2022-03-11

We report a case of 16-year-old man in cardiogenic shock secondary to On-X mitral prosthesis dysfunction due leaflet embolization through aortic mechanical prosthesis. He underwent an emergency redo valve replacement and, few days later, removal by open surgery with full recovery.

10.1016/j.jaccas.2024.102237 article EN cc-by-nc-nd JACC Case Reports 2024-02-09
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