- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Infectious Aortic and Vascular Conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Abdominal vascular conditions and treatments
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Cell Adhesion Molecules Research
- Esophageal and GI Pathology
- Protease and Inhibitor Mechanisms
- Connective tissue disorders research
- Liver Disease and Transplantation
- Renal and Vascular Pathologies
- Cardiac Valve Diseases and Treatments
- Angiogenesis and VEGF in Cancer
- Intracranial Aneurysms: Treatment and Complications
- Atherosclerosis and Cardiovascular Diseases
- Transplantation: Methods and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Eosinophilic Esophagitis
- Renal Transplantation Outcomes and Treatments
- Radiation Dose and Imaging
- Hemodynamic Monitoring and Therapy
- Cardiac Structural Anomalies and Repair
- Climate Change and Health Impacts
Université Paris-Est Créteil
2019-2025
Laboratoire de Recherche Vasculaire Translationnelle
2020-2025
Hôpitaux Universitaires Henri-Mondor
2016-2025
Centre Hospitalier Universitaire Henri-Mondor
2017-2024
Université Paris Cité
2017-2024
Hôpital Bichat-Claude-Bernard
2019-2024
Inserm
2017-2024
Université Gustave Eiffel
2022-2024
Assistance Publique – Hôpitaux de Paris
2017-2023
Sorbonne Université
2022-2023
Abstract Early diagnosis of acute mesenteric ischemia (AMI) remains a clinical challenge, and no biomarker has been consistently validated. We aimed to assess the accuracy three promising circulating biomarkers for diagnosing AMI—citrulline, intestinal fatty acid-binding protein (I-FABP), d -lactate. A cross-sectional diagnostic study enrolled AMI patients admitted stroke center controls with abdominal pain another origin. included 129 patients—50 79 controls. Plasma citrulline...
Background Data on the prognostic impact of type A aortic dissection involving common carotid arteries (CCAs) are scarce. Methods status CCAs were available in 1106 patients who underwent surgery for acute DeBakey 1 recruited a retrospective, multicentre European registry, that is, ERTAAD. Postoperative neurological complications defined as ischaemic stroke, haemorrhagic stroke and/or global brain ischaemia. Results Patients without artery dissection, those with unilateral or bilateral CCA...
IgE type immunoglobulins and their specific effector cells, mast cells (MCs), are associated with abdominal aortic aneurysm (AAA) progression. In parallel, immunoglobulin-producing B organised in tertiary lymphoid organs (TLOs) within the wall, have also been linked to aneurysmal We aimed at investigating potential role mechanism linking local MCs, TLO production progression.Through histological assays conducted on human surgical samples from AAA patients, we uncovered that activated MCs...
Abstract There is a need for new targets to specifically localize inflammatory foci, usable in wide range of organs. Here, we hypothesized that the cleaved molecular form CD31 suitable target imaging inflammation. We evaluated bioconjugate D-P8RI, synthetic peptide binds all cells with CD31, an experimental rat model sterile acute Male Wistar rats were injected turpentine oil into gastrocnemius muscle two days before 99m Tc-HYNIC-D-P8RI (or its analogue L-Proline) SPECT/CT or [ 18 F]FDG...
<b><i>Introduction:</i></b> Saccular aneurysms are thought to have a worse prognosis than fusiform in humans, due hemodynamic reasons. However, data comparing and biology saccular lacking. The main objective was evaluate the impact of aneurysm morphology on intra-luminal thrombus (ILT) formation activity. <b><i>Methods:</i></b> Forty Lewis rats were randomly divided into 2 groups 20: “saccular” (Group A) “fusiform” B) aneurysms. Decellularized...
Airway complications are frequent after lung transplantation (LT), as they affect up to 23% of recipients. The implication perioperative extracorporeal membrane oxygenation (ECMO) support and haemodynamic instability has never been specifically assessed. first aim this study was explore the impact ECMO on bronchial anastomotic dehiscence (BAD) at Day 90 LT. This prospective observational monocentric analysed BAD in all consecutive patients who underwent LT Bichat Claude Bernard Hospital,...
Purpose: The study sought to estimate the prevalence of primary non-aortic lesions (PNAL) unrelated extension aortic dissection (AD) in a cohort patients with Marfan syndrome (MFS). Methods: Adult presenting pathogenic FBN1 mutations and an available pan-aortic contrast-enhanced CTA eight French MFS clinics from April October 2018 were included. Clinical radiological data, particularly presence PNAL (including aneurysm ectasia), retrospectively analyzed. Results: Out 138 patients, 28 (20.3%)...
Thymic function decreases progressively with age but may be boosted in certain circumstances. We questioned whether heart transplantation was such a situation and thymic related to the onset of rejection. Twenty-eight antithymocyte globulin-treated transplant recipients were included. Patients diagnosed for an antibody-mediated rejection on endomyocardial biopsy had higher proportion circulating recent emigrant CD4+ T cells cell receptor excision circle levels than other transplanted...
Background In Marfan syndrome (MFS), an aortic or peripheral arterial dilatation is usually the consequence of dissection. Non-dissecting distal and aneurysms (DAPA) are barely described. We sought to determine incidence prognostic impact non-dissecting DAPA, requiring a surgical repair in large population patients with MFS. Methods The referred French MFS reference center were included prospective database, treated for DAPA between 2013 2020 retrospectively reviewed. first-line therapy was...
We report a case of 16-year-old man in cardiogenic shock secondary to On-X mitral prosthesis dysfunction due leaflet embolization through aortic mechanical prosthesis. He underwent an emergency redo valve replacement and, few days later, removal by open surgery with full recovery.