A5018202220- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Pleural and Pulmonary Diseases
- Radiomics and Machine Learning in Medical Imaging
- Photodynamic Therapy Research Studies
- Transplantation: Methods and Outcomes
- Airway Management and Intubation Techniques
- Nanoplatforms for cancer theranostics
- Ultrasound in Clinical Applications
- Myasthenia Gravis and Thymoma
- Medical Imaging Techniques and Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Venous Thromboembolism Diagnosis and Management
- Viral Infections and Immunology Research
- Respiratory Support and Mechanisms
- Trauma Management and Diagnosis
- Pneumothorax, Barotrauma, Emphysema
- Gyrotron and Vacuum Electronics Research
- Cancer Genomics and Diagnostics
- Atomic and Subatomic Physics Research
Chiba University
2015-2024
Toronto General Hospital
2019-2024
University of Toronto
2019-2024
University Health Network
2019-2024
NorthEast Regional Epilepsy Group
2018
Health Net
2018
National Hospital Organization
2015-2017
Ospedale Papa Giovanni XXIII
2016
University of Occupational and Environmental Health Japan
2015
Chiba University Hospital
2015
<b><i>Background:</i></b> Elastography is a relatively new technology that can generate images reflective of tissue stiffness (elasticity). Neoplastic usually stiffer than normal structures. <b><i>Objectives:</i></b> The aim this study was to evaluate the feasibility and utility elastography when combined with convex-probe endobronchial ultrasound (CP-EBUS) for predicting localizing metastatic lymph nodes during transbronchial needle aspiration...
Lung adenocarcinoma is classified morphologically into five histological subtypes according to the WHO classification. While each subtype correlates with a distinct prognosis, molecular basis has not been fully elucidated. Here we conducted DNA methylation analysis of 30 lung cases annotated predominant and three normal using Infinium BeadChip. Unsupervised hierarchical clustering revealed subgroups different levels: high-, intermediate-, low-methylation epigenotypes (HME, IME, LME)....
Abstract Background During endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA), the sonographic findings of B‐mode imaging, as well elastography, can be obtained noninvasively and used for prediction nodal metastasis. Methods Patients with lung cancer or suspected who underwent EBUS‐TBNA were recorded prospectively reviewed retrospectively. Both elastographic independently evaluated each lymph node. The features classified according to previously published criteria....
Abstract Tumor spread through air spaces (STAS) in non-small-cell lung cancer (NSCLC) is known to influence a poor patient outcome, even patients presenting with early-stage disease. However, the pre-operative diagnosis of STAS remains challenging. With progress radiomics-based analyses several attempts have been made predict based on radiological findings. In present study, NSCLC which located peripherally and tumors ≤ 2 cm size computed tomography (CT) that were potential candidates for...
Spontaneous pneumothorax is common in relatively young, healthy patients. The risk factors for postoperative recurrence after correction are not fully understood.We retrospectively reviewed the records of patients who underwent surgery spontaneous between January 2006 and October 2017. We assessed possible causing using univariate multivariate analyses. then used inverse probability treatment-weighted method to correct confounding factors.Postoperative was observed 41 233 (17.6%). A...
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a valid modality for nodal lung cancer staging. The sonographic features of EBUS helps determine suspicious lymph nodes (LNs). To facilitate this use method, machine-learning-based computer-aided diagnosis (CAD) medical imaging has been introduced in clinical practice. This study investigated the feasibility CAD prediction metastasis using endobronchial ultrasound images. Image data patients who underwent...
Appropriate device selection is crucial for endobronchial foreign body removal using a bronchoscope. In pediatric patients, bronchoscopy requires the use of thin due to narrow access airway, limiting range useful devices. We herein review our experience in with focus on type bronchoscope and instruments used comparison literature, investigate utility mini grasping basket forceps (FG-55D, Olympus® ; Zero Tip™ , Airway Retrieval Basket, Boston Scientific).Between April 2008 2016, bodies were...
Background: Robot-assisted thoracic surgery (RATS) has become widely used for mediastinal procedures since 2018 when it was included in insurance coverage Japan. Few studies have compared the surgical outcomes of RATS with more established video-assisted (VATS) approach to surgery. We aimed compare perioperative VATS and examine advantages a single institutional cohort.
Conventional flexible bronchoscopy has not achieved the high diagnostic yield for intrapulmonary lesions as seen with image-guided transthoracic biopsy. A thin convex probe endobronchial ultrasound bronchoscope (TCP-EBUS) a 5.9-mm tip was designed to improve peripheral access over conventional EBUS bronchoscopes facilitate real-time sampling of under guidance.TCP-EBUS inserted into distal airways ex-vivo human lungs assess bronchial accessibility relative clinically available bronchoscopes....
Anastomotic failure of a gastric tube inserted for reconstruction following esophagectomy, which is relatively rare, causes pleural infection and persistent irritation, leading to communication with the pulmonary parenchyma. Although several interventions have been reported treat such broncho-gastric fistulas, refractory cases remain. We herein report successful treatment by endoscopic bronchial occlusion an endobronchial Watanabe spigot in 2 patients who suffered from above complication.
ObjectiveSevere pulmonary embolism is often managed with thrombolysis. We sought to determine whether endobronchial ultrasound (EBUS)-guided transbronchial thrombolysis remained effective at lower alteplase doses, the goal of minimizing potential bleeding risk.MethodsYorkshire pigs were anesthetized and ventilated. Preformed autologous blood clots administered into bilateral arteries via EBUS-guided injection. After documenting baseline clot sizes, was injected using a 25-gauge needle...
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a relatively rare subtype of lung malignancy. According to revised 2015 World Health Organization (WHO) criteria for the pathological diagnosis LCNEC, markers must be examined by immunohistochemistry. In this study, we reevaluated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) samples patients previously diagnosed with LCNEC using WHO criteria.Clinical tissue that had been obtained EBUS-TBNA between...