A5101957850- Health, Nursing, Elderly Care
- Healthcare during COVID-19 Pandemic
- Healthcare Regulation
- Neuroscience and Neural Engineering
- Drug-Induced Hepatotoxicity and Protection
- Brucella: diagnosis, epidemiology, treatment
- Family and Patient Care in Intensive Care Units
- Axon Guidance and Neuronal Signaling
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Research on Leishmaniasis Studies
- Consumer Attitudes and Food Labeling
- Neural dynamics and brain function
- Transcranial Magnetic Stimulation Studies
- Toxoplasma gondii Research Studies
- 3D Printing in Biomedical Research
- Poisoning and overdose treatments
- Electrochemical Analysis and Applications
- Dental Health and Care Utilization
- Metastasis and carcinoma case studies
- Sensory Analysis and Statistical Methods
- Public Health in Brazil
- Aluminum toxicity and tolerance in plants and animals
- Maternal and Neonatal Healthcare
- Endoplasmic Reticulum Stress and Disease
- Pediatric Pain Management Techniques
Centre d’Immunologie de Marseille-Luminy
2024
Hospitais da Universidade de Coimbra
2019-2023
University of Coimbra
2017-2021
Chartered Institute of Management Accountants
2018
Pearson (United States)
2017
Universitat Autònoma de Barcelona
2014-2017
Centro de Investigación Biomédica en Red
2014-2017
Biomedical Research Networking Center on Neurodegenerative Diseases
2014-2017
University of Beira Interior
2016-2017
Universidade Federal de Minas Gerais
2016
Objective. In this study we present the development and testing in a rat model of self-opening neural interface (SELINE), novel flexible peripheral interface. Approach. This polyimide-based electrode has three-dimensional structure that provides an anchorage system to nerve confers stability after implant. geometry been achieved by means plastic deformation polyimide. Mechanical electrochemical characterizations have performed prove integrity with very good results. Functionality SELINEs for...
Objective. As artificial prostheses become more refined, they are most often used as a therapeutic option for hand amputation. By contrast to extra- or intraneural interfaces, regenerative nerve electrodes designed enable electrical interfaces with regrowing axonal bundles of injured nerves, aiming achieve high selectivity recording and stimulation. However, the developed designs pose an obstacle regrowth mechanisms due low transparency cause impairment regeneration. Approach. Here we...
A 25-year-old man admitted for generalised muscle pain with an insidious onset 3 years ago. He had exercise intolerance and decrease in strength, requiring gait support. was previously healthy, no chronic medication or recent history of drugs toxics. National vaccination plan actualised hepatitis B tetanus vaccines administered 10 2 years, respectively, before symptom onset. No analytical, imaging electromyography changes were found. Muscle biopsy revealed inflammatory infiltrate...
ABSTRACT The unfolded protein response (UPR) is a key stress resistance pathway that has become potential target for improving the efficacy of cancer chemotherapy. UPR involves activation three ER-resident sensors: PERK, IRE-1 and ATF6 with different signalling outcomes leading to cell death or survival. These cell-fate decisions are difficult predict result complex interaction downstream events have differences in their dynamics interplay. characteristics still poorly defined due lack...
Q fever is a zoonotic infection caused by the pathogen Coxiella burnetii, and patients can present with wide spectrum of clinical manifestations, depending on whether it an acute or chronic infection. We case 61-year-old male fatigue, posterior thoracalgia, intermittent fever, night sweats weight loss for month. After extensive workup, he was diagnosed large-vessel vasculitis. The FDG-PET/CT scan suggested active vasculitis specifically in thoracic aorta, proximal abdominal subclavian...
Os inibidores das Janus Associated Kinases (JAK) sao uma estrategia recente direcionada para o tratamento de diversas patologias como a artrite reumatoide, psoriase, alopecia areata e diversos tipos cancro. Contudo, estes medicamentos estao associados reacoes adversas graves, estando subentendida importância da monitorizacao farmacoterapeutica dos doentes submetidos tratamentos. O objetivo do estudo foi efetuar revisao diferentes JAK aprovados no mercado nacional internacional, as suas...
Introduction Needle procedures can be very painful for children and generate stress anxiety. Virtual reality (VR) has been used to enhance a child's distraction pain control during these procedures. This study aims identify the advantages limitations of VR in using needles pediatrics. Methods Studies were limited aged 4–18 years undergoing procedure involving use with goggles, headset, or helmet. A comprehensive search strategy CINAHL Complete, MedicLatina, Medline B-on, LILACS, SciELO...
<h3>Background</h3> Janus associated kinase family (JAK 1, JAK 2, 3 and Tyk2) are molecular targets for enzyme inhibition that represent a useful strategy the treatment of different clinical conditions, such as arthritis, psoriasis, organ rejection multiple cancer types. However, inhibitors with major adverse drug reactions (ADR), which underlines importance close monitoring by healthcare professionals. <h3>Purpose</h3> The aim this study was to review all available on pharmaceutical market,...
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Drug-induced liver injury is hardly diagnosed, considering not only the wide range of hepatotoxic substances but also diversity associated phenotypes and absence specific biomarkers. Symptom chronology, drug or toxic exposure, temporal association help to establish diagnosis. Exposure isopropanol has known rare effects. We report clinical case a 33-year-old female hairdresser admitted hospital with fatigue, epigastric pain, jaundice. She presented following values: aspartate...