Alexander Wang

ORCID: 0000-0001-5911-2590
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About
Contact & Profiles
Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Photosynthetic Processes and Mechanisms
  • Computational Geometry and Mesh Generation
  • Algal biology and biofuel production
  • Generative Adversarial Networks and Image Synthesis
  • Multimodal Machine Learning Applications
  • Digital Image Processing Techniques
  • Reproductive System and Pregnancy
  • Advanced Combinatorial Mathematics
  • Retinoids in leukemia and cellular processes
  • Industrial Vision Systems and Defect Detection
  • Advanced Image and Video Retrieval Techniques
  • Reproductive Physiology in Livestock
  • Estrogen and related hormone effects
  • Spine and Intervertebral Disc Pathology
  • Amino Acid Enzymes and Metabolism
  • Machine Learning in Healthcare
  • Data Visualization and Analytics
  • Anesthesia and Pain Management
  • Polyamine Metabolism and Applications
  • Nausea and vomiting management
  • Family and Patient Care in Intensive Care Units
  • Anesthesia and Sedative Agents
  • Phytase and its Applications
  • Photonic and Optical Devices

Oregon National Primate Research Center
2023-2024

University of Maryland, Baltimore
2024

Children's National
2023

Cell Biotech (South Korea)
2023

Biocat
2023

North Asheboro Middle School
2022

Columbia University
2021

Orlando VA Medical Center
2020

University of Central Florida
2020

University of Toronto
2020

Enhancers are cis-acting elements capable of regulating transcription in a distance and orientation-independent manner. A subset enhancers occupied by RNA polymerase II (RNAP II) transcribed to produce long non-coding RNAs termed eRNAs. We thoroughly investigated the association between eRNA productivity various chromatin marks transcriptional regulators mouse embryonic stem cells (ESCs) through an integrative approach. found that eRNA-producing exhibited elevated levels active mark H3K27Ac,...

10.4161/epi.26597 article EN Epigenetics 2013-10-17

BACKGROUND Management of prostate cancer that either is detectable by specific antigen (PSA) measurements after curative intent or has spread outside its capsule a serious problem. Innovative, nontoxic approaches to the disease are required. One approach might be therapy with retinoids. Retinoid activities mediated two distinct families transcription factors: retinoic acid receptors (RARs) and retinoid X (RXRs), which can induce transcriptional activation through DNA sites inhibiting factor...

10.1002/(sici)1097-0045(19970701)32:2<115::aid-pros6>3.0.co;2-l article EN The Prostate 1997-07-01

Abstract Objective Endocervical mucus production is a key regulator of fertility throughout the menstrual cycle. With cycle-dependent variability in quality and quantity, cervical can either facilitate or block sperm ascension into upper female reproductive tract. This study seeks to identify genes involved hormonal regulation production, modification, through profiling transcriptome endocervical cells from non-human primate, rhesus macaque (Macaca mulatta). Intervention We treated...

10.1093/biolre/ioae121 article EN Biology of Reproduction 2024-08-08

Abstract Astaxanthin (AX) is a carotenoid pigment with antioxidant properties widely used as feed supplement. Wild‐type strains of Phaffia rhodozyma naturally produce low AX yields, but we increased yields 50‐fold in previous research using random mutagenesis P. CBS6938 and fermentation optimization. On that study, genome changes were linked phenotype, relevant metabolic not resolved. In this the wild‐type superior mutant grown chemically defined media instrumented fermenters. Differential...

10.1002/bit.28332 article EN cc-by-nc Biotechnology and Bioengineering 2023-01-14

ABSTRACT Chimeric antigen receptor (CAR) T cells are an effective treatment for some blood cancers. However, the lack of tumor-specific surface antigens limits their wider use. We identified a set that limited in expression to cancer and central nervous system (CNS). developed CAR against one these antigens, LINGO1, which is widely expressed Ewing sarcoma (ES). To prevent CNS targeting, we engineered LINGO1 lacking integrin ⍺ 4 (A4 ko ), adhesion molecule essential migration across...

10.1101/2024.02.08.579002 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-02-11

10.1109/ecai61503.2024.10607535 article EN 2022 14th International Conference on Electronics, Computers and Artificial Intelligence (ECAI) 2024-06-27

OBJECTIVES The purpose of this study was to describe overall screening, prevention, and treatments for pediatric delirium at various neonatal intensive care units (NICUs), cardiac (CICUs), (PICUs) from the Pediatric Pharmacy Association (PPA) membership. primary objective identify number respondents that had a defined delirium-based protocol. secondary objectives included identification assessment tools used, first- second-line treatment options, monitoring practices antipsychotics...

10.5863/1551-6776-28.6.540 article EN The Journal of Pediatric Pharmacology and Therapeutics 2023-10-01

Attribute prior avoidance entails subconscious or willful non-modeling of (meta)attributes that datasets are oft born with, such as the 40 semantic facial attributes associated with CelebA and CelebA-HQ datasets. The consequences this infirmity, we discover, especially stark in state-of-the-art deep generative models learned on these just model pixel-space measurements, resulting an inter-attribute bias-laden latent space. This viscerally manifests itself when perform face manipulation...

10.48550/arxiv.1907.12917 preprint EN cc-by arXiv (Cornell University) 2019-01-01

Endocervical mucus production is a key regulator of fertility throughout the menstrual cycle. With cycle-dependent variability in quality and quantity, cervical can either facilitate or block sperm ascension into upper female reproductive tract. This study seeks to identify genes involved hormonal regulation production, modification, through profiling transcriptome endocervical cells from non-human primate, Rhesus Macaque (Macaca mulatta).

10.1101/2023.05.18.541362 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-05-18

For integrated silicon photonics to mature as an industry platform, robust methods for measuring and extracting the geometry of fabricated waveguides are needed. Due cost time needed SEM or AFM imaging, a method waveguide variability though optical measurements is often preferred. Here, we present study regression-based machine learning (ML) techniques that enable such extraction while maintaining compatibility with wafer-scale measurements. We first explicitly investigate issue non-unique...

10.1117/12.2594255 article EN 2021-07-30

Banknotes are special notes authorized by the government and carry monetary value. As a result, there incentives for criminals to create counterfeit. The goal of this study is models using machine learning techniques that can accurately classify banknote as authentic or fake. methods used were logistic regression artificial neural networks. An open-source data set was obtained split into 7 sub-datasets, multiple created model data. There total models, each corresponding one sub-datasets....

10.47611/jsrhs.v11i3.3777 article EN Journal of Student Research 2022-08-31

10.1002/bit.28138 article EN Biotechnology and Bioengineering 2023-04-12

10.1002/bit.28144 article EN Biotechnology and Bioengineering 2023-10-13

A small triangulation of the sphere product can be found in lower dimensions by computer search and is known few other cases: Klee Novik constructed a centrally symmetric $\mathbb{S}^i\times \mathbb{S}^{d-i-1}$ with $2d+2$ vertices for all $d\geq 3$ $1\leq i\leq d-2$; they also proposed balanced $\mathbb{S}^1\times \mathbb{S}^{d-2}$ $3d$ or $3d+2$ vertices. In this paper, we provide another $(2d+2)$-vertex $\mathbb{S}^2\times \mathbb{S}^{d-3}$. We construct first \mathbb{S}^{d-3}$ $4d$...

10.48550/arxiv.1811.08505 preprint EN other-oa arXiv (Cornell University) 2018-01-01

10.1016/j.ejc.2019.103043 article EN publisher-specific-oa European Journal of Combinatorics 2019-11-05

In this demonstration, we present a generalized platform customized to suit the needs of fast power-efficient and autonomous delivery system. As an application deployed mapping localization system based on combination sensor sources. An online navigation algorithm utilizes map information deliver destination in mapped area.

10.1109/metrocad48866.2020.00013 article EN 2020-02-01

Sketch drawings capture the salient information of visual concepts. Previous work has shown that neural networks are capable producing sketches natural objects drawn from a small number classes. While earlier approaches focus on generation quality or retrieval, we explore properties image representations learned by training model to produce images. We show this generative, class-agnostic produces informative embeddings images novel examples, classes, and even datasets in few-shot setting....

10.48550/arxiv.2009.04806 preprint EN other-oa arXiv (Cornell University) 2020-01-01

Astaxanthin (AX) is a carotenoid pigment with antioxidant properties. AX used widely in the animal feed industry as supplement. Wild-type strains of Phaffia rhodozyma naturally produce low yields, but we increased yields 50-fold previous research using random mutagenesis P. CBS6938 and fermentation optimisation. Genome sequencing linked phenotype genome changes production relevant metabolic were not resolved. In this study, wild-type superior mutant grown chemically defined media...

10.22541/au.165218774.43718228/v1 preprint EN Authorea (Authorea) 2022-05-10

Pichia pastoris ( Komagataella phaffii ) is a fast-growing methylotrophic yeast with the ability to assimilate several carbon sources such as methanol, glucose, or glycerol. It has been shown have outstanding secretion capability variety of heterologous proteins. In previous studies, we engineered P. co-express E. coli AppA phytase and HAC1 transcriptional activator using bidirectional promoter. Phytase production was characterised in shake flasks did not reflect industrial conditions....

10.22541/au.165816380.04897659/v1 preprint EN Authorea (Authorea) 2022-07-18

BACKGROUND Management of prostate cancer that either is detectable by specific antigen (PSA) measurements after curative intent or has spread outside its capsule a serious problem. Innovative, nontoxic approaches to the disease are required. One approach might be therapy with retinoids. Retinoid activities mediated two distinct families transcription factors: retinoic acid receptors (RARs) and retinoid X (RXRs), which can induce transcriptional activation through DNA sites inhibiting factor...

10.1002/(sici)1097-0045(19970701)32:2<115::aid-pros6>3.3.co;2-4 article EN The Prostate 1997-07-01
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