- Gamma-ray bursts and supernovae
- SAS software applications and methods
- Stellar, planetary, and galactic studies
- Astronomy and Astrophysical Research
- Astrophysical Phenomena and Observations
- Astronomical Observations and Instrumentation
- Astro and Planetary Science
- Cell Image Analysis Techniques
- Single-cell and spatial transcriptomics
- Galaxies: Formation, Evolution, Phenomena
- Astrophysics and Cosmic Phenomena
- Pulsars and Gravitational Waves Research
- Cancer Genomics and Diagnostics
- Scientific Computing and Data Management
- Genetics, Bioinformatics, and Biomedical Research
- Adaptive optics and wavefront sensing
- Health, Environment, Cognitive Aging
- Geophysics and Gravity Measurements
- Calibration and Measurement Techniques
- Radio Astronomy Observations and Technology
- Advanced Fluorescence Microscopy Techniques
- Astrophysics and Star Formation Studies
- Cosmology and Gravitation Theories
- Medical Imaging Techniques and Applications
- Evolution and Genetic Dynamics
European Bioinformatics Institute
2023-2025
University of Cambridge
2012-2023
Max Planck Society
2004-2018
Institute of Astronomy
2012
European Southern Observatory
2009-2011
Max Planck Institute for Extraterrestrial Physics
2004-2011
University College Dublin
2009
Excellence Cluster Universe
2009
Technical University of Munich
2009
Thüringer Landessternwarte Tautenburg
2009
Gamma-ray bursts (GRBs) serve as powerful probes of the early Universe, with their luminous afterglows revealing locations and physical properties star forming galaxies at highest redshifts, potentially locating first generation (Population III) stars. Since GRB have intrinsically very simple spectra, they allow robust redshifts from low signal to noise spectroscopy, or photometry. Here we present a photometric redshift z~9.4 for Swift-detected 090429B based on deep observations...
Identifying transcript location in cells where specific RNAs occur within a cell or tissue has been limited by technology and imaging capabilities. Expansion microscopy allowed for better visualization of small structures expanding the tissues with polymer- hydrogel-based system. Alon et al. combined expansion long-read situ RNA sequencing, resulting more precise transcripts. This method, termed “ExSeq” was used to detect RNAs, both new transcripts those previously demonstrated localize...
We describe the construction of GROND, a 7-channel imager, primarily designed for rapid observations gamma-ray burst afterglows. It allows simultaneous imaging in Sloan g' r' i' z' and near-infrared JHK bands. GROND was commissioned at MPI/ESO 2.2 m telescope La Silla (Chile) April 2007, first results its performance calibration are presented.
In this paper we describe the first data release of Visible and Infrared Survey Telescope for Astronomy (VISTA) Deep Extragalactic Observations (VIDEO) survey. VIDEO is a ~12degree^2 survey in near-infrared Z,Y,J,H K_s bands, specifically designed to enable evolution galaxies large structures be traced as function both epoch environment from present day out z=4, active galactic nuclei (AGN) most massive up into reionization. With its depth area, will able fully explore period Universe where...
The VST Photometric Halpha Survey of the Southern Galactic Plane and Bulge (VPHAS+) is surveying southern Milky Way in u, g, r, i at 1 arcsec angular resolution. Its footprint spans latitude range -5 < b +5 all longitudes south celestial equator. Extensions around Centre to latitudes +/-10 bring much Bulge. This ESO public survey, begun on 28th December 2011, reaches down 20th magnitude (10-sigma) will provide single-epoch digital optical photometry for 300 million stars. observing strategy...
The VLT Survey Telescope (VST) ATLAS is an optical ugriz survey aiming to cover ~4700deg^2 of the Southern sky similar depths as Sloan Digital Sky (SDSS). From reduced images and object catalogues provided by Cambridge Astronomical Surveys Unit we first find that median seeing ranges from 0.8 arcsec FWHM in i 1.0 u, significantly better than 1.2-1.5 for SDSS. 5 sigma magnitude limit stellar sources r_AB=22.7 all bands these limits are at least faint SDSS more equivalent galaxy photometry...
Abstract A holistic understanding of tissue and organ structure function requires the detection molecular constituents in their original three-dimensional (3D) context. Imaging mass cytometry (IMC) enables simultaneous up to 40 antigens transcripts using metal-tagged antibodies but has so far been restricted two-dimensional imaging. Here we report development 3D IMC for multiplexed analysis at single-cell resolution demonstrate utility technology by human breast cancer samples. The resulting...
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals institutes across diverse modalities facing these have designed specification process (OME-NGFF) address needs. This paper brings together wide range those members describe cloud-optimized itself-OME-Zarr-along with tools data resources available today increase FAIR access remove barriers...
We present optical and near-infrared photometry of the afterglow long Gamma-Ray Burst GRB 070802 at redshift 2.45 obtained with ESO/MPI 2.2 m telescope equipped multi-channel imager GROND. Follow-up observations in g'r'i'z' JHK_S bands started ~17 min extended up to 28 h post burst. find an increase brightness early times, which can be explained by superposition reverse forward shock (FS) emission or onset FS. Additionally, we detect a strong broad-band absorption feature i' band, interpret...
We report on the detection by Swift of GRB 080913, and subsequent optical/near-infrared follow-up observations GROND, which led to discovery its optical/NIR afterglow recognition high-z nature via a spectral break between i' z' bands. Spectroscopy obtained at ESO-VLT revealed continuum extending down λ = 9400 Å, zero flux for 7500 Å<λ < we interpret as onset Gunn–Peterson trough z 6.695± 0.025 (95.5% confidence level), making 080913 highest-redshift gamma-ray burst (GRB) date, more distant...
Context. Thirteen years after the discovery of first afterglows, nature dark gamma-ray bursts (GRB) still eludes explanation: while each long-duration GRB typically has an X-ray afterglow, optical/NIR emission is only seen for 40–60% them.
(Abridged) Until recently the information inferred from gamma-ray burst follow-up observations was mostly limited to optically bright afterglows, biasing all demographic studies against sight-lines that contain large amounts of dust. Here, we present GRB afterglow and host for a sample bursts are exemplary previously missed ones because high visual extinction along sight-line. This facilitates an investigation properties, geometry location absorbing dust these poorly-explored galaxies,...
In this paper, we describe the routine photometric calibration of data taken with VISTA infrared camera (VIRCAM) instrument on ESO Visible and Infrared Survey Telescope for Astronomy (VISTA) telescope. The broad-band ZYJHKs are directly calibrated from Two Micron all Sky (2MASS) point sources visible in every image. We present empirical transformations between 2MASS VISTA, Wide-Field Camera systems regions low reddening. investigate long-term performance VISTA+VIRCAM. An investigation...
Fermi can measure the spectral properties of gamma-ray bursts over a very large energy range and is opening new window on prompt emission these energetic events. Localizations by instruments in combination with follow-up Swift provide accurate positions for observations at longer wavelengths leading to determination redshifts, true budget, host galaxy facilitate comparison pre-Fermi bursts. Multi-wavelength were performed afterglows four high detected Fermi/LAT : GRB090323, GRB090328,...
We report on the surprisingly high metallicity measured in two absorption systems at redshift, detected Very Large Telescope spectrum of afterglow gamma-ray burst GRB 090323. The systems, redshift z=3.5673 and z=3.5774 (separation Delta v ~ 660 km/s), are dominated by neutral gas interstellar medium parent galaxies. From singly ionized zinc sulfur, we estimate oversolar metallicities [Zn/H] =+0.29+/-0.10 [S/H] = +0.67+/- 0.34, blue red absorber, respectively. These highest ever galaxies z>3....
The detection of GeV photons from gamma-ray bursts (GRBs) has important consequences for the interpretation and modelling these most-energetic cosmological explosions. full exploitation high-energy measurements relies, however, on accurate knowledge distance to events. Here we report discovery afterglow subsequent redshift determination GRB 080916C, first detected by Fermi Gamma-Ray Space Telescope with high significance at >0.1 GeV. Observations were done 7-channel imager GROND 2.2m...
Abstract We report the discovery of a narrow stellar stream crossing constellations Sculptor and Fornax in Southern celestial hemisphere. The portion detected Data Release 1 photometry ATLAS survey is at least 12° long, while its width ≈0 $_{.}^{\circ}$25. colour–magnitude diagram this halo sub-structure consistent with metal-poor [Fe/H] ≲ −1.4 population located heliocentric distance 20 ± 2 kpc. There are three globular clusters that could tentatively be associated stream: NGC 7006, 7078...
Context. Chemically inhomogeneous populations are observed in most globular clusters, but not open clusters. Cluster mass seems to play a key role the existence of multiple populations.
We present the curation and verification of a new combined optical near infrared dataset for cosmology astrophysics, derived by combining u g r i -band imaging from Kilo-Degree Survey (KiDS) Z Y J H K s VISTA Kilo degree Infrared Galaxy (VIKING) survey. This is unrivaled in cosmological surveys due to combination its area (458 deg 2 before masking), depth ( ≤ 25), wavelength coverage ). survey depth, area, (most importantly) allows significant reductions systematic uncertainties (i.e....
We present observations and analysis of the broadband afterglow Swift GRB 071025. Using optical infrared (RIYJHK) photometry, we derive a photometric redshift 4.4 < z 5.2; at this our simultaneous multicolour begin ~30 s after trigger in host frame during initial rising phase afterglow. associate light curve peak 580 observer with formation forward shock, giving an estimate Lorentz factor Gamma_0 ~ 200. The red spectral energy distribution (even regions not affected by Lyman-alpha break)...
Context: The link between the duration of GRBs and nature their progenitors remains disputed. Short bursts (with durations less than ~2 s) are frequently observed, technically more difficult to localize, exhibit significantly fainter afterglows. Aims: It is critical importance establish whether burst can reliably distinguish different GRB population models collapsars compact stellar mergers. Swift 090426 provides an unique opportunity address this question. Its (T_90=1.28 places firmly in...
In this paper we describe the routine photometric calibration of data taken with VIRCAM instrument on ESO VISTA telescope. The broadband ZYJHKs are directly calibrated from 2MASS point sources visible in every image. We present empirical transformations between and VISTA, WFCAM systems for regions low reddening. investigate long-term performance VISTA+VIRCAM. An investigation dependence interstellar reddening leads to these conclusions: (1) For all filters, a linear colour-dependent...