A5046569227- Genetic and phenotypic traits in livestock
- Animal Virus Infections Studies
- Ruminant Nutrition and Digestive Physiology
- Viral gastroenteritis research and epidemiology
- Genetic Mapping and Diversity in Plants and Animals
- Animal Disease Management and Epidemiology
- Virus-based gene therapy research
- Reproductive Physiology in Livestock
- Animal Nutrition and Physiology
- Genetics and Plant Breeding
- Effects of Environmental Stressors on Livestock
- Bioenergy crop production and management
- Cancer-related molecular mechanisms research
- Livestock Management and Performance Improvement
- Molecular Biology Techniques and Applications
- Gut microbiota and health
- Helminth infection and control
- Microbial infections and disease research
- Amphibian and Reptile Biology
- Agriculture and Farm Safety
- Genomics and Phylogenetic Studies
- melanin and skin pigmentation
- Ultrasound in Clinical Applications
- Agricultural Systems and Practices
- Agriculture Sustainability and Environmental Impact
University of Nevada, Reno
2022-2024
AgResearch
2019-2023
Iowa State University
2013-2021
Allegheny College
2015
Abstract Dramatic improvements in measuring genetic variation across agriculturally relevant populations (genomics) must be matched by identifying and trait such many environments (phenomics). Identifying the most critical opportunities challenges genome to phenome (G2P) research is focus of this paper. Previously (Genome Biol, 23(1):1–11, 2022), we laid out how Agricultural Genome Phenome Initiative (AG2PI) will coordinate activities with USA federal government agencies expand...
Fitting covariates representing the number of haplotype alleles rather than single nucleotide polymorphism (SNP) may increase genomic prediction accuracy if linkage disequilibrium between quantitative trait loci and SNPs is inadequate. The objectives this study were to evaluate accuracy, bias computation time Bayesian methods that fit fixed-length haplotypes or SNPs. Genotypes at 37,740 common Illumina BovineSNP50 high-density panels phased for ~58,000 New Zealand dairy cattle. Females born...
Porcine reproductive and respiratory syndrome (PRRS) is one of the most important swine diseases in world genetic selection pigs for increased resistance to PRRS an attractive method improve health status herd. This study compared phenotypic responses infection with two genetically distinct type 2 virus (PRRSV) isolates: NVSL-97-7895 (NVSL) KS-2006-72109 (KS06), evaluated whether single nucleotide polymorphism (SNP) WUR10000125 (WUR) on chromosome 4 that was associated viral load weight gain...
A host can adopt two response strategies to infection: resistance (reduce pathogen load) and tolerance (minimize impact of infection on performance). Both may be under genetic control could thus targeted for improvement. Although there is evidence that supports a basis porcine reproductive respiratory syndrome (PRRS), it not known whether pigs also differ genetically in tolerance. We determined what extent have been shown vary PRRS exhibit variation Multi-trait linear mixed models random...
Microbial community profiles have been associated with a variety of traits, including methane emissions in livestock. These can be difficult and expensive to obtain for thousands samples (e.g. accurate association microbial traits), therefore the objective this work was develop low-cost, high-throughput approach capture diversity rumen microbiome. Restriction enzyme reduced representation sequencing (RE-RRS) using ApeKI or PstI, two bioinformatic pipelines (reference-based reference-free)...
Porcine reproductive and respiratory syndrome (PRRS) is a devastating disease in the swine industry. Identification of host genetic factors that enable selection for improved performance during PRRS virus (PRRSV) infection would reduce impact this on animal welfare production efficiency. We conducted genomewide association study (GWAS) analyses data from 13 trials approximately 200 commercial crossbred nursery-age piglets were experimentally infected with 1 2 type isolates PRRSV (NVSL...
Gender of the calf whose birth initiates lactation could influence whole milk yield dam due to hormonal influences on mammary gland development, or through gender effects gestation length. Fetal late yields because cows become pregnant at peak lactation. The sequences in parities 1–3 were assessed by separately fitting animal models datasets from New Zealand comprising 274 000 Holstein Friesian and 85 Jersey cows, decreasing 12 4 parity 3. initiated a female rather than male was associated...
Rumen microbes break down complex dietary carbohydrates into energy sources for the host and are increasingly shown to be a key aspect of animal performance. Host genotypes can combined with microbial DNA sequencing predict performance traits or related environmental impact, such as enteric methane emissions. Metagenome profiles were generated from 3139 rumen samples, collected 1200 dual purpose ewes, using restriction enzyme-reduced representation (RE-RRS). Phenotypes available (CH4) carbon...
Abstract Polymorphic species provide an excellent system to study population divergence because different phenotypes often face diverse selection pressures within their shared environment. Previous studies have demonstrated that color morphs of P lethodon cinereus (striped and unstriped), which vary in degree melanin‐based coloration, temporally seasonal activity differ metrics associated with stress physiology. Despite the known association between coloration disease resistance among...
Abstract Background Porcine reproductive and respiratory syndrome (PRRS) is a threat to pig production worldwide. Our objective was understand mechanisms of persistence PRRS virus (PRRSV) in tonsil. Transcriptome data from tonsil samples collected at 42 days post infection (dpi) were generated by RNA-seq NanoString on 51 pigs that selected contrast the two PRRSV isolates used, NVSL KS06, high low viral level dpi, favorable unfavorable genotypes genetic marker (WUR) for putative resistance...
High resistance (the ability of the host to reduce pathogen load) and tolerance maintain high performance at a given are two desirable traits for producing animals that resilient infections. For Porcine Reproductive Respiratory Syndrome (PRRS), one most devastating swine diseases worldwide, studies have identified substantial genetic variation in pigs, but evidence has so far been inconclusive. Resistance usually considered as static traits. In this study, we used longitudinal viremia...
DAO Diseases of Aquatic Organisms Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 116:205-212 (2015) - DOI: https://doi.org/10.3354/dao02915 Salamanders increase their feeding activity when infected with pathogenic chytrid fungus Batrachochytrium dendrobatidis Alexandra Hess*, Caroline McAllister, Joseph DeMarchi, Makenzie Zidek, Julie Murone, Matthew D. Venesky*,** Department Biology, Allegheny...
Genetic and antigenic variability between Porcine Reproductive Respiratory Syndrome Virus (PRRSV) isolates has encumbered vaccine development. Here, the genetic basis of PRRSV antibody response was assessed using data from experimental infection trials commercial crossbred weaner pigs across with one two distinct isolates, NVSL-97-7895 (~750 pigs) KS-2006-72109 (~450 pigs). Objectives were to estimate parameters response, measured as sample positive ratio (S:P) N-protein specific IgG in...
Abstract Background Producing animal protein while reducing the animal’s impact on environment, e.g., through improved feed efficiency and lowered methane emissions, has gained interest in recent years. Genetic selection is one possible path to reduce environmental of livestock production, but these traits are difficult expensive measure many animals. The rumen microbiome may serve as a proxy for due its role digestion. Restriction enzyme-reduced representation sequencing (RE-RRS)...
Porcine reproductive and respiratory syndrome (PRRS) is one of the most important global swine diseases from both an economic animal welfare standpoint. PRRS has plagued US industry for over 25 yr, containment virus (PRRSV) been unsuccessful to date. The primary phase PRRS, tracked by serum viremia, typically clears between 21 42 d postinfection (dpi) but tonsils are a main site PRRSV persistence can be detected in excess 150 dpi. Measuring tonsil (TV) levels at late stages infection (6 7 wk...
Genomic prediction of the pig’s response to porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) would be a useful tool in swine industry. This study investigated accuracy genomic based on SNP60 Beadchip data using training validation datasets from populations with different genetic backgrounds that were challenged PRRSV isolates. averaged 0.34 for viral load (VL) 0.23 weight gain (WG) following experimental challenge, which demonstrates selection could used improve infection....
Abstract As technological advancements enhance our ability to study population genetics, we must understand how the intrinsic properties of datasets influence decisions make when designing experiments. Filtering parameter thresholds, such as call rate and minimum minor allele frequency (MAF), are known affect inferences structure in reduced representation sequencing (RRS) studies. However, it is unclear what extent impacts these choices vary across datasets. Here, reviewed literature on...
Abstract Increased climatic variability represents the most significant threat to arid rangeland production systems. We set out describe land use behavior of sheep and associations between phenotypes body weight (BW) gain via investigation GPS data paired with vaginal temperature sensors characterize fitness under stress. During a fortnight spanning Aug 19th Sep 1st, 2023, we deployed 200 199 collars on extensively managed Australian Merinos, ⅝ Merino X ⅜ Rambouillet composite line in...
Abstract Gastrointestinal nematode (GIN) infection adversely affects the performance and well-being of forage-based sheep throughout world. The study objectives were to estimate longitudinal differences between birth seasons production systems for lamb postweaning growth indicators GIN infection. Data collected on Katahdin lambs within a single flock from 2006 2022. Lambs born in either winter or fall reared conventional certified organic systems. Four sub-flocks defined as combination...
Abstract Microbial community profiles have been associated with a variety of traits, including methane emissions in livestock, however, these can be difficult and expensive to obtain for thousands samples. The objective this work was develop low-cost, high-throughput approach capture the diversity rumen microbiome. Restriction enzyme reduced representation sequencing (RE-RRS) using ApeK I or Pst I, two bioinformatic pipelines (reference-based reference-free) were compared 16S rRNA gene...