A5080065714- Meningioma and schwannoma management
- Cerebrospinal fluid and hydrocephalus
- Epilepsy research and treatment
- Glioma Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Intraoperative Neuromonitoring and Anesthetic Effects
- Neurofibromatosis and Schwannoma Cases
- Neuroscience and Neuropharmacology Research
- Surgical Simulation and Training
- Traumatic Brain Injury and Neurovascular Disturbances
- Pharmacological Effects and Toxicity Studies
- Facial Trauma and Fracture Management
- Anatomy and Medical Technology
- Intracranial Aneurysms: Treatment and Complications
- Congenital Heart Disease Studies
- Neurosurgical Procedures and Complications
- Kawasaki Disease and Coronary Complications
- Traumatic Ocular and Foreign Body Injuries
- Advanced MRI Techniques and Applications
- Aortic Disease and Treatment Approaches
- Augmented Reality Applications
- Neuroblastoma Research and Treatments
- Trigeminal Neuralgia and Treatments
- Brain Metastases and Treatment
- Spinal Dysraphism and Malformations
Medical University of Vienna
2021-2025
Universitätsklinikum Erlangen
2021
Augmented reality (AR) is increasingly being used to improve surgical planning and assist in real time procedures. A retrospective investigation was conducted study its feasibility pediatric epilepsy surgery at a single institution. Functional neuronavigation using multimodal imaging data (fMRI, DTI-tractography, PET, SPECT, sEEG) were augment the navigation by transferring MRI reconstructions as AR maps into microscope overlaying field. Altogether, 43 patients (17 female, 0-18 yrs, mean 9...
The discovery of cellular tumor networks in glioblastoma, with routes malignant communication extending far beyond the detectable margins, has highlighted potential supramarginal resection strategies. Retrospective data suggest that these approaches may improve long-term disease control. However, their application is limited by proximity critical brain regions and vasculature, posing challenges for validation randomized trials. Anterior temporal lobectomy (ATL) a standardized surgical...
Vestibular schwannoma (VS) surgery is feasible for various tumor sizes that are inappropriate wait and scan or radiosurgery. The predictive value of 2 grading systems was investigated postoperative hearing preservation (HP) in a large series.Retrospective analysis.Neurosurgical patient database the University Erlangen queried between 2014 2017.Retrospective single-center analysis on 138 VSs operated via retrosigmoidal approach. mean size 20.4 mm (SD, 7.6 mm) with fundal infiltration 67.4%....
To evaluate the neurosurgical and economical effectiveness of a newly launched intraoperative high field (3-Tesla) magnetic resonance MR imaging suite for pediatric tumor epilepsy neurosurgery. Altogether, 148 procedures 124 patients (mean age 8.7 years, range 0 – 18 years) within 2.5-year periode were undertaken in two- room MRI (iopMRI) suite. Surgeries mainly performed intractable (n=81, 55%) or brain tumors (n=65, 44%) supine (n=113, 76%) prone (n=35, 24%) position. The mean time iopMRI...
Objective: Management of patients after failed epilepsy surgery is still challenging. Advanced diagnostic and intraoperative tools including magneto-encephalography (MEG) as well neuronavigation magnetic resonance imaging (iopMRI) may contribute to a better postoperative seizure outcome in this patient group.Methods: We retrospectively analyzed consecutive reoperation for medically refractory at the University Erlangen between 1988 2017. Inclusion criteria were available MEG, iopMRI data....
Objective: The aim of this retrospective cohort study was to assess seizure and memory outcomes following temporal lobe surgery in patients suffering from medically refractory epilepsy (TLE) hippocampal sclerosis (HS).Methods: A monocentric data analysis performed consecutive who were operated on during 2002-2018. In the first decennium, standard resections (TLR) predominately performed, later, antero-temporal (ATLR) mainly performed. Seizure over time assessed according ILAE/Engel...
Objectives: We recently introduced a navigated, robot-driven laser beam craniotomy for use with stereoelectroencephalography (SEEG) applications. This method was intended to substitute the hand-held electric power drill in an ex vivo study. The purpose of this non-recovery pilot study acquire data depth control unit device, test feasibility cutting bone channels, and assess dura perforation possible cortex damage related cold ablation. Methods: Multiple holes suitable SEEG channels were...
<title>Abstract</title> <bold>Background: </bold>Augmented reality (AR) is increasingly being used to improve surgical planning and assist in real time procedures. A retrospective investigation was conducted study its role pediatric epilepsy surgery at a single institution. <bold>Methods: </bold>Functional neuronavigation using multimodal imaging data (fMRI, DTI-tractography, PET, SPECT, sEEG) were augment the navigation by transferring 3D reconstructions as AR maps into microscope...
Motivation: Immediate changes in functionality during brain surgery tumor and epilepsy patients are worth investigating order to improve prediction of surgical outcomes. Goal(s): We want implement a preprocessing-pipeline for pre- post-resection data that allows comparison between both scans the application further analysis methods. Approach: propose two-step approach, where we first pre-register anatomical MNI-space with consideration resection area then use this second step preprocessing...
INTRODUCTION: Direct facial nerve stimulation during vestibular schwannoma surgery (VSS) allows preservation of the in its continuity. However, prognostication post- operative function remains challinging. METHODS: In total, 51 patients (median age 52yrs; 19-84) with unilateral VS size 20mm;10-50) were included. Intraoperative neuromonitoring consisted auditory evoked potentials (AEPs), direct and CoMEPs. An anodal via subdermal corkscrew electrodes on position C3 or C4 a cathode near Cz...
Facial and cochlear nerve preservation in large vestibular schwannomas is a major challenge. Bimanual pincers or plate-knife dissection techniques have been described as crucial for preservation. The authors demonstrate recently applied diamond knife technique to peel the nerves from tumor capsule. This minimizes trauma significantly, complete resection of schwannoma without any facial palsy hearing possible. illustrate this during surgery 2.6-cm 27-year-old male patient resulting normal...