A5010275556- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Spinal Fractures and Fixation Techniques
- Head and Neck Surgical Oncology
- Vascular Malformations Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Moyamoya disease diagnosis and treatment
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Facial Trauma and Fracture Management
- Cerebrovascular and Carotid Artery Diseases
- Management of metastatic bone disease
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury Research
- Medical Imaging and Analysis
- Musculoskeletal pain and rehabilitation
- Infectious Diseases and Tuberculosis
- Epilepsy research and treatment
- Cervical and Thoracic Myelopathy
- Glioma Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Craniofacial Disorders and Treatments
- Acute Ischemic Stroke Management
Johannes Gutenberg University Mainz
2019-2025
University Medical Center of the Johannes Gutenberg University Mainz
2019-2025
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
2021-2022
University Hospital of Geneva
2009-2018
University of Geneva
2010-2018
Hôpital Beau-Séjour
2014-2017
University of Bonn
2010
Background and Purpose— According to the International Study of Unruptured Intracranial Aneurysms (ISUIA), anterior circulation (AC) aneurysms <7 mm in diameter have a minimal risk rupture. It is general experience, however, that communicating artery (AcoA) are frequent mostly rupture at mm. The aim study was assess whether AcoA behave differently from other AC aneurysms. Methods— Information about 932 patients newly diagnosed with intracranial between November 1, 2006, March 31, 2012,...
OBJECTIVE Spinal ependymomas are rare glial neoplasms. Because their incidence is low, only a few larger studies have investigated this condition. There no clear data concerning prognosis and therapy. The aim of the study was to describe natural history, perioperative clinical course, local tumor control adult patients with spinal who were surgically treated under modern treatment standards. METHODS authors performed multicenter retrospective study. They identified 158 had received surgical...
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The discovery of cellular tumor networks in glioblastoma, with routes malignant communication extending far beyond the detectable margins, has highlighted potential supramarginal resection strategies. Retrospective data suggest that these approaches may improve long-term disease control. However, their application is limited by proximity critical brain regions and vasculature, posing challenges for validation randomized trials. Anterior temporal lobectomy (ATL) a standardized surgical...
Pathogenesis of intracranial aneurysm is complex and the precise biomechanical processes leading to their rupture are uncertain. The goal our study was characterize aneurysmal wall histologically correlate histological characteristics with clinical radiological factors used estimate risk rupture. A new biobank domes resected at Geneva University Hospitals (Switzerland) used. Histological analysis revealed that unruptured aneurysms have a higher smooth muscle cell (SMC) content lower...
Background Intracranial aneurysms (IAs) are more common in women than men; however, there is still limited knowledge on sex‐dependent differences regarding aneurysm location, multiplicity, rupture risk, risk factors, and histopathology. Methods This cross‐sectional, consecutive cohort study examined whether IAs differ geometry, histology between sexes. Results We included 982 patients (714 women, 268 men) totaling 1484 (1056 unruptured, 397 ruptured). A total of 363 (36.97%) had multiple...
<b>Objective</b> To evaluate whether anterior lumbar interbody fusion (ALIF) is superior to transforaminal (TLIF) in cases of post-discectomy syndrome (PDS). <b>Methods</b> In this retrospective study, we analyzed the consecutive results 83 patients operated for PDS refractory conservative treatment. A total 46 underwent ALIF via a retroperitoneal approach; 37 TLIF. Both types were augmented by means pedicle screw instrumentation. Early and delayed complications registered within course...
Abstract Anaplastic meningioma is seldom encountered. Moreover, distant metastasis extremely rare, with only a handful cases reported. Here, we report the case of 74-year-old female patient who underwent combined cranial and endonasal approach for an extensive spheno-orbital anaplastic (WHO grade III), followed by adjuvant radiotherapy. Although local tumor control was achieved, she presented lung 2 years later. The then died from pulmonary complications related to chest metastasis. On basis...
The Oswestry Spinal Risk Index (OSRI) was designed to predict life expectancy of patients presenting with spinal metastases. It integrates the most predictive items existing scores and is calculated using not more than two items: General condition primary tumor.The purpose this study externally validate OSRI in a large cohort compare it established scores.We retrospectively identified 211 consecutive surgical symptomatic We collected clinical radiographic data, such as Karnofsky Performance...
Abstract Numerous materials of implants used for cranioplasty after decompressive craniectomy (DC) have been investigated to meet certain demanded key features, such as stability, applicability, and biocompatibility. We aimed evaluate the feasibility safety biocompatible calcium-phosphate (CaP) compared polymethylmethacrylate (PMMA) implants. In this retrospective observational cohort study, medical records all patients who underwent between January 1st, 2015, 2022, were reviewed....
OBJECTIVE Although several studies have suggested that the incidence of intracranial aneurysms (IAs) is higher in smokers, prevalence subarachnoid hemorrhage (SAH) smokers remains uncertain. It unclear whether smoking additionally contributes to formation multiple and risk rupture. The aim this study was determine associated with IA formation, multiplicity, or METHODS Patients from prospective multicenter @neurIST database (n = 1410; 985 females [69.9%]) were reviewed for presence SAH,...