A5100385499- Diet and metabolism studies
- Histiocytic Disorders and Treatments
- Polymer Surface Interaction Studies
- Genetics and Neurodevelopmental Disorders
- Adipose Tissue and Metabolism
- RNA and protein synthesis mechanisms
- Mesoporous Materials and Catalysis
- Molecular Junctions and Nanostructures
- Supramolecular Self-Assembly in Materials
- Sirtuins and Resveratrol in Medicine
- Pain Mechanisms and Treatments
- Trace Elements in Health
- Ion channel regulation and function
- Genetic and rare skin diseases.
- Tuberous Sclerosis Complex Research
- Healthcare innovation and challenges
- Gut microbiota and health
- Advanced Glycation End Products research
- Urban Heat Island Mitigation
- Cerebral Palsy and Movement Disorders
- Community Development and Social Impact
- Extracellular vesicles in disease
- Telomeres, Telomerase, and Senescence
- Social Media in Health Education
- Protease and Inhibitor Mechanisms
Sichuan University
2021-2025
West China Hospital of Sichuan University
2021-2025
Guangzhou Medical University
2022-2024
Nanjing University of Science and Technology
2024
UNSW Sydney
2024
Shanxi Medical University
2023-2024
First Hospital of Shanxi Medical University
2024
Kingmed Diagnostics
2022
University of Science and Technology of China
2022
The University of Melbourne
2017-2021
The orientation-specific immobilization of antibodies onto nanoparticles, to preserve antibody–antigen recognition, is a key challenge in developing targeted nanomedicines. Herein, we report the targeting ability metal–phenolic network (MPN)-coated gold nanoparticles with surface-physisorbed against respective antigens. MPN coatings were self-assembled from metal ions (FeIII, CoII, CuII, NiII, or ZnII) cross-linked tannic acid. Upon physisorption antibodies, all particle systems exhibited...
Abstract Supramolecular complexation is a powerful strategy for engineering materials in bulk and at interfaces. Metal–phenolic networks (MPNs), which are assembled through supramolecular complexes, have emerged as suitable candidates surface particle owing to their diverse properties. Herein, we examine the dynamics of MPNs during thermal transformation processes. Changes local network including enlarged pores, ordered aromatic packing, metal relocation arise from treatment air or an inert...
Abstract A large number of data suggest that caloric restriction (CR) has a protective effect on myocardial ischemia/reperfusion injury (I/R) in the elderly. However, mechanism is still unclear. In this study, we created I/R model vivo by ligating mice left coronary artery for 45 min followed reperfusion. C57BL/6J wild-type were randomly divided into young group fed ad libitum (y-AL), aged (a-AL) and calorie (a-CR, 70% diet restriction), 6 weeks. The area infarction was measured Evan’s...
Cobalt–tannic acid-coated gold nanoparticles are found to better inhibit amyloid fibril formation than other metal-based tannic particles.
Abstract Functional coatings are of considerable interest because their fundamental implications for interfacial assembly and promise numerous applications. Universally adherent materials have recently emerged as versatile functional coatings; however, such generally limited to catechol, ( ortho ‐diphenol)‐containing molecules, building blocks. Here, we report a facile, biofriendly enzyme‐mediated strategy assembling wide range molecules (e.g., 14 representative in this study) that do not...
Tendon xanthoma is very rare. We report FDG PET/CT findings of tendon in a 33-year-old man. On image, it manifested as multiple symmetric nodules with an SUVmax 9.37, located the tendons both elbows, knees and ankles. The final pathology supported diagnosis xanthoma.
The development of noninvasive approaches to precisely control neural activity in mammals is highly desirable. Here, we used the ion channel transient receptor potential ankyrin-repeat 1 (TRPA1) as a proof principle, demonstrating remote near-infrared (NIR) activation endogenous neuronal channels mice through an engineered nanoagonist. This achievement enables specific neurostimulation nongenetically modified mice. Initially, target-based screening identified flavins photopharmacological...
Multifunctional host–guest supramolecular PCD-acetal-PGEA/Ad-PEG-FA polyplexes showing FA-targeting and acid-triggered intracellular gene release resulted in good transfection efficiency low cytotoxicity.
Abstract Functional coatings are of considerable interest because their fundamental implications for interfacial assembly and promise numerous applications. Universally adherent materials have recently emerged as versatile functional coatings; however, such generally limited to catechol, ( ortho ‐diphenol)‐containing molecules, building blocks. Here, we report a facile, biofriendly enzyme‐mediated strategy assembling wide range molecules (e.g., 14 representative in this study) that do not...
Abstract Supramolecular complexation is a powerful strategy for engineering materials in bulk and at interfaces. Metal–phenolic networks (MPNs), which are assembled through supramolecular complexes, have emerged as suitable candidates surface particle owing to their diverse properties. Herein, we examine the dynamics of MPNs during thermal transformation processes. Changes local network including enlarged pores, ordered aromatic packing, metal relocation arise from treatment air or an inert...
The purpose of this study was to determine which method, individual information-centered (IIC) or group (GIC), is more efficient in recovering missing physical activity (PA) data.A total 2,758 Chinese children and youth aged 9 17 years old (1,438 boys 1,320 girls) wore ActiGraph GT3X/GT3X+ accelerometers for 7 consecutive days. Those with no data (n = 900) were used form a nonmissing sample, which, based on semisimulation approach, create set evaluate recovery methods, including 2 IIC 22 GIC...
Abstract Langerhans cell histiocytosis only involving the posterior elements of spine is rare. We report case a 7-year-old boy who has pain and restricted motion his neck. 18 F-FDG PET/CT revealed an osteolytic lesion in fourth cervical vertebra. The high uptake with SUVmax 8.01. An operation was performed, final pathological finding histiocytosis.
Abstract LRP1, the low-density lipoprotein receptor 1, would be a novel candidate epilepsy gene according to our bioinformatic results and animal study. In this study, we explored role of LRP1 in Epilepsy whether Beta-hydroxybutyrate, principal ketone body ketogenic diet can treat caused by deficiency. UAS/GAL4 system was used establish different genotype models. Flies were given Standard, High-sucrose, food randomly. The bang-sensitive test performed on flies seizure-like behavior assessed....
Abstract LRP1, the low-density lipoprotein receptor 1, would be a novel candidate gene of Epilepsy according to our bioinformatic results and animal study. In this study, we explored role LRP1 in whether Beta-hydroxybutyrate, principal ketone body ketogenic diet, can treat epilepsy caused by deficiency. UAS/GAL4 system was used establish different genotype models. Flies were given Standard, High-sucrose, food randomly. The bang-sensitive test performed on flies seizure-like behavior...