Shámila Ismael

ORCID: 0000-0001-7028-4756
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About
Contact & Profiles
Research Areas
  • Diet and metabolism studies
  • Gut microbiota and health
  • Nutritional Studies and Diet
  • Dietary Effects on Health
  • Sodium Intake and Health
  • Diet, Metabolism, and Disease
  • Adipokines, Inflammation, and Metabolic Diseases
  • Pancreatitis Pathology and Treatment
  • Long-Term Effects of COVID-19
  • Liver Disease Diagnosis and Treatment
  • Blood Pressure and Hypertension Studies
  • Metabolism and Genetic Disorders
  • Bariatric Surgery and Outcomes
  • Superconducting Materials and Applications
  • Hops Chemistry and Applications
  • Peroxisome Proliferator-Activated Receptors
  • Sperm and Testicular Function
  • Breastfeeding Practices and Influences
  • Diabetes Treatment and Management
  • COVID-19 Clinical Research Studies
  • Ginseng Biological Effects and Applications
  • Regulation of Appetite and Obesity
  • Adipose Tissue and Metabolism
  • Infant Nutrition and Health
  • Pharmacological Effects and Toxicity Studies

Universidade Nova de Lisboa
2021-2025

University of Strathclyde
2023

Tampere University
2023

University of Cambridge
2023

Karlsruhe Institute of Technology
2023

Kyoto University
2023

University of Twente
2023

Institute of Electrical and Electronics Engineers
2023

X-Fab (Germany)
2023

University of Houston
2023

The Mediterranean diet (MD) has been recommended for type 2 diabetes (T2D) treatment. impact of in shaping the gut microbiota is well known, particularly MD. However, link between MD and outcome improvement not completely clear. This study aims to evaluate role modulation by a nonpharmacological intervention patients with T2D. In this 12-week single-arm pilot study, nine participants received individual nutritional counseling sessions promoting Gut microbiota, biochemical parameters, body...

10.3390/nu13041228 article EN Nutrients 2021-04-08

Adiponectin/leptin ratio, triacylglycerols, and waist-to-hip ratio explained almost half of HOMA-IR variance in the context obesity. This study provides evidence to support adipose tissue dysfunction as a central feature pathophysiology obesity insulin resistance. Early identification individuals at higher risk developing metabolic complications through assessment staging its transient phenotypes can contribute improve therapeutic decision-making.

10.1152/ajpendo.00273.2022 article EN AJP Endocrinology and Metabolism 2022-11-09

Gut microbiota modulation might constitute a mechanism mediating the effects of beer on health. In this randomized, double-blinded, two-arm parallel trial, 22 healthy men were recruited to drink 330 mL nonalcoholic (0.0% v/v) or alcoholic (5.2% daily during 4-week follow-up period. Blood and faecal samples collected before after intervention was analyzed by 16S rRNA gene sequencing. Drinking for 4 weeks did not increase body weight fat mass changed significantly serum cardiometabolic...

10.1021/acs.jafc.2c00587 article EN cc-by Journal of Agricultural and Food Chemistry 2022-06-15

BACKGROUND/OBJECTIVES: Indole-3-propionic acid (IPA) is a tryptophan-derived microbial metabolite that has been associated with protective effects against inflammatory and metabolic diseases.However, there lack of knowledge regarding the IPA under physiological conditions at intestinal level.MATERIALS/METHODS: Human epithelial Caco-2 cells were treated for 2, 24, and/ or 72 h its precursors -indole, tryptophan, propionate -at 1, 10, 100, 250, 500 μM to assess cell viability, integrity,...

10.4162/nrp.2023.17.4.616 article EN Nutrition Research and Practice 2023-01-01

The FEEDMI Study (NCT03663556) evaluated the influence of infant feeding (mother's own milk (MOM), donor human (DHM) and formula) on fecal microbiota composition alkaline phosphatase (ALP) activity in extremely very preterm infants (≤32 gestational weeks). In this observational study, were recruited within first 24 h after birth. Meconium samples collected at four time points (between 2nd 26th postnatal days. Fecal was analyzed by RT-PCR 16S rRNA sequencing. ALP activity, a proposed specific...

10.3390/nu13051564 article EN Nutrients 2021-05-06

Abstract Background Subjects with obesity exhibit changes in gut microbiota composition and function (i.e. dysbiosis) that contribute to metabolic dysfunction, including appetite impairment. Although bariatric surgery is an effective treatment for a great impact on weight loss, some subjects show regain due increased energy intake after the surgery. This involves promote control, but it seems insufficient completely restore obesity-associated dysbiosis — possible contributor regain. Thus,...

10.1186/s13063-023-07383-0 article EN cc-by Trials 2023-05-29

Introduction Empowerment lifestyle programs are needed to reduce the risk of hypertension. Our study compared effectiveness two empowerment-based approaches toward blood pressure (BP) reduction: salt reduction-specific program vs. healthy general program. Methods Three hundred and eleven adults (median age 44 years, IQR 34–54 years) were randomly assigned a reduction ( n = 147) or 164). The outcome measures urinary sodium (Na + ) potassium (K excretion, systolic (SBP) diastolic (DBP)...

10.3389/fpubh.2023.1277355 article EN cc-by Frontiers in Public Health 2023-11-13

10.1016/s2772-5723(23)00155-3 article EN cc-by-nc-nd Gastro Hep Advances 2023-01-01

Although elevated blood levels of trimethylamine N -oxide (TMAO) have been associated with atherosclerosis development in humans, the role its gut microbiota-derived precursor, TMA, this process has not yet deciphered. Taking into account, and fact that increased intestinal fatty acid absorption contributes to onset progression, study aimed evaluate effect TMA on a cell line mimics human enterocytes. Caco-2 cells were treated 250 μM for 24 h. Fatty was assessed by measuring...

10.1017/jns.2023.91 article EN cc-by-nc-nd Journal of Nutritional Science 2023-01-01

Objective: Salt restriction and potassium (K) intake can lower blood pressure (BP) reduce the risk for cardiovascular (CV) diseases. However, it is still unclear which approaches are most effective in changing diet behavior. We evaluated impact of two education prevention programs promoting healthy eating habits general population. Design method: A total 311 adults (20–70 years) responsible acquiring making their meals were randomly assigned to one 2 multi-component educational (intervention...

10.1097/01.hjh.0000748176.73228.01 article EN Journal of Hypertension 2021-04-01

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10.1017/s002966512100080x article EN Proceedings of The Nutrition Society 2021-01-01
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