A5051957181- Epigenetics and DNA Methylation
- RNA modifications and cancer
- RNA Research and Splicing
- Nutrition, Genetics, and Disease
- DNA Repair Mechanisms
- Digestive system and related health
- Virus-based gene therapy research
- Cell Adhesion Molecules Research
- Redox biology and oxidative stress
- Genomics and Chromatin Dynamics
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- Protease and Inhibitor Mechanisms
- Bioactive Compounds and Antitumor Agents
- interferon and immune responses
- Cell death mechanisms and regulation
- Genomics, phytochemicals, and oxidative stress
- Cancer Research and Treatments
- Cancer-related Molecular Pathways
Harbin Medical University
2025
Southern University of Science and Technology
2024
Industrial Optical Measurement Systems (United States)
2018
First Bethune Hospital of Jilin University
2010-2012
Jilin University
2009
Abstract Epithelial–mesenchymal transition (EMT) is a fundamental cellular process frequently hijacked by cancer cells to promote tumor progression, especially metastasis. EMT orchestrated complex molecular network acting at different layers of gene regulation. In addition transcriptional regulation, posttranscriptional mechanisms may also play role in EMT. Here, we performed pooled CRISPR screen analyzing the influence 1,547 RNA-binding proteins on cell motility colon and identified...
<p>Table S6. The list of differentially expressed proteins upon DDX6 or EDC4 knockout</p>
<p>Table S1. The list of oligos used in the study</p>
<p>Table S4. The list of differentially expressed genes upon DDX6 or EDC4 knockout</p>
<p>Table S1. The list of oligos used in the study</p>
<p>Table S2. The list and sequences of gRNAs</p>
<p>Table S4. The list of differentially expressed genes upon DDX6 or EDC4 knockout</p>
<div>Abstract<p>Epithelial–mesenchymal transition (EMT) is a fundamental cellular process frequently hijacked by cancer cells to promote tumor progression, especially metastasis. EMT orchestrated complex molecular network acting at different layers of gene regulation. In addition transcriptional regulation, posttranscriptional mechanisms may also play role in EMT. Here, we performed pooled CRISPR screen analyzing the influence 1,547 RNA-binding proteins on cell motility colon and...
<p>Table S5. The list of peaks and genes enriched in DDX6-eCLIP-seq</p>
<p>Table S2. The list and sequences of gRNAs</p>
<p>Table S3. The list of candidate genes</p>
<p>Figure S1-S8</p>
<div>Abstract<p>Epithelial–mesenchymal transition (EMT) is a fundamental cellular process frequently hijacked by cancer cells to promote tumor progression, especially metastasis. EMT orchestrated complex molecular network acting at different layers of gene regulation. In addition transcriptional regulation, posttranscriptional mechanisms may also play role in EMT. Here, we performed pooled CRISPR screen analyzing the influence 1,547 RNA-binding proteins on cell motility colon and...
<p>Figure S1-S8</p>
<p>Table S6. The list of differentially expressed proteins upon DDX6 or EDC4 knockout</p>
<p>Table S5. The list of peaks and genes enriched in DDX6-eCLIP-seq</p>
<p>Table S3. The list of candidate genes</p>