A5100678183- Genomics and Phylogenetic Studies
- Advanced biosensing and bioanalysis techniques
- Plant biochemistry and biosynthesis
- MicroRNA in disease regulation
- Gut microbiota and health
- RNA Interference and Gene Delivery
- Plant Pathogens and Fungal Diseases
- Aquaculture disease management and microbiota
- RNA modifications and cancer
- Coral and Marine Ecosystems Studies
- Plant Reproductive Biology
- Diet and metabolism studies
- Cellular transport and secretion
- Plant Molecular Biology Research
- Dietary Effects on Health
- Epigenetics and DNA Methylation
- Bone Metabolism and Diseases
- Retinal Development and Disorders
- Photosynthetic Processes and Mechanisms
- Ubiquitin and proteasome pathways
- Insect-Plant Interactions and Control
- Plant Physiology and Cultivation Studies
- Plant and Fungal Species Descriptions
- Angiogenesis and VEGF in Cancer
- Plant Gene Expression Analysis
University of Science and Technology of China
2025
Hainan Medical University
2022-2024
Zhejiang A & F University
2024
Yangzhou University
2023
Kunming University of Science and Technology
2018-2022
Kaohsiung Medical University
2022
Shandong Provincial Hospital
2021
Shandong First Medical University
2021
Changsha Central Hospital
2021
Shanghai Jiao Tong University
2016-2020
Glandular trichomes are generally considered biofactories that produce valuable chemicals. Increasing glandular trichome density is a very suitable way to improve the productivity of these metabolites, but little known about regulation formation. Phytohormone jasmonate (JA) promotes initiation in various plants, its mechanism also unknown. By searching transcription factors regulated by JA Artemisia annua, we identified novel homeodomain-leucine zipper factor, HOMEODOMAIN PROTEIN 1 (AaHD1),...
Summary Glandular trichomes and cuticles are both specialized structures that cover the epidermis of aerial plant organs. The former commonly regarded as ‘biofactories’ for producing valuable natural products. latter generally considered barriers defending plants against abiotic biotic stresses. However, regulatory network their formation relationship remains largely elusive. Here we identify a homeodomain‐leucine zipper (HD‐ZIP) IV transcription factor, AaHD8, directly promoting expression...
Artemisinin, the frontline drug against malaria, is a sesquiterpenoid extracted from Artemisia annua. Light has been proposed to play an important role in activation of artemisinin biosynthesis. Here, we report basic leucine zipper transcription factor (TF) AaHY5 as key regulator light-induced biosynthesis artemisinin. We show that overlaps with genes response light and A. annua tissues. Analysis overexpression RNAi-suppression lines suggests positive expression accumulation complements hy5...
Abstract Glandular secreting trichomes (GSTs) synthesize and secrete large quantities of secondary metabolites, some which have well-established commercial value. An example is the anti-malarial compound artemisinin, synthesized in GSTs Artemisia annua. Accordingly, there considerable interest understanding processes that regulate GST density as a strategy to increase artemisinin production. In this study, we identified GST-specific WRKY transcription factor from A. annua, AaGSW2, positively...
At most synapses, presynaptic Ca 2+ channels are positioned near vesicle release sites, and increasing this distance reduces synaptic strength. We examined the lateral membrane mobility of L-type at photoreceptor ribbon synapses tiger salamander ( Ambystoma tigrinum ) retina. Movements individual were tracked by coupling quantum dots to an antibody against extracellular α 2 δ 4 channel subunit. antibodies labeled terminals colocalized with glycoprotein voltage-gated 1.4 (Ca V 1.4) 1...
Vesicle release from rod photoreceptors is regulated by Ca(2+) entry through L-type channels located near synaptic ribbons. We characterized sites and kinetics of vesicle in salamander rods using total internal reflection fluorescence microscopy to visualize fusion individual vesicles. A small number vesicles were loaded brief incubation with FM1-43 or a dextran-conjugated, pH-sensitive form rhodamine, pHrodo. Labeled organelles matched the diffraction-limited size fluorescent microspheres...
The diabetic autonomic neuropathy is one of the most common complications in type 2 diabetes mellitus (T2DM), especially gastrointestinal (GAN), which occurs up to 75% patients. study aimed investigate gut microbiota composition, structure, and function T2DM patients with GAN (T2DM_GAN) set a link between clinical characteristics patients.DNA was extracted from fecal samples three groups using kit method: healthy volunteers (n = 19), 76), T2DM_GAN 27). Sequencing 16S ribosomal DNA performed...
Objective Gut microbiota have been thought to play a role in the emergence of obesity and metabolic disorders, thus dietary fiber may be an effective strategy for management by modulating gut microbiota. The aim present study was investigate effects konjaku flour (KF) supplementation on treating regulating intestinal obese adults. Methods In 5-week, randomized, double-blind, place-controlled trial, sixty-nine volunteers aged 25 35 with body mass index ≥28 kg/m 2 were randomly assigned...
Seven strains, ICMP 19430T, 19429, 19431, WSM4637, WSM4638, WSM4639 and WSM4640, were isolated from nitrogen-fixing nodules on roots of the invasive South African legume Dipogon lignosus (subfamily Papilionoideae, tribe Phaseoleae) in New Zealand Western Australia, their taxonomic positions investigated by using a polyphasic approach. All seven strains grew at 10-37 °C (optimum, 25-30 °C), pH 4.0-9.0 6.0-7.0) with 0-2 % (w/v) NaCl (optimum growth absence NaCl). On basis 16S rRNA gene...
Sensitive and portable quantification of biomarkers has particular significance in the monitoring treatment clinical diseases. Conventional immunoassays were accustomed to introducing or incorporating enzymes for signal amplification, which commonly suffered from poor stability inferior tolerance. Herein, we constructed a novel nonenzyme amplification methodology based on fluorogenic Ag+-tetrazolate aggregation coupled with silver corrosion sensitization biomarker determination. A...
The gut microbiota is believed to play a significant role in psychological and gastrointestinal symptoms heroin addicts. However, the underlying mechanism remains largely unknown. We show here that addicts had decrease body mass index (BMI) abnormal serum D-lactic acid (DLA), endotoxin (ET) diamine oxidase (DAO) levels during their withdrawal stage, suggesting potential intestinal injury. microbial profiles mouse model with dependence showed slightly decreased alpha diversity, as well higher...
A Gram-negative, heterotrophic, marine bacterium, designated strain SW-11(T), was isolated from the reef-building coral Isopora palifera in Kenting, Taiwan. Cells were rods and motile by a single polar flagellum. The grew at 10-45 °C (optimum, 30-35 °C), pH 7.0-8.0 7.5) with 2.0-4.0 % NaCl 2.5-3.0 %). lipids comprised phosphatidylethanolamine, phosphatidylglycerol, phosphatidylserine, diphosphatidylglycerol four unknown phospholipids. Isoprenoid quinones consisted of ubiquinone 9 (78.8 %) 8...
Osteosarcoma (OS) has been demonstrated to be difficult cure due its potently malignant metastasis. Therefore, new therapeutic approaches blocking the metastatic potential of OS are urgently required improve outcomes for patients. In present study, anti‑metastatic capacity sea cucumber (Cucumaria frondosa) fucoidan (Cf‑Fuc) was evaluated on osteosarcoma cells by cell adhesion assay, Transwell assay and U2OS migration assay. The underlying mechanism dynamic remodeling cytoskeleton also...
A bacterial strain, designated SW-3 T , was isolated from the reef-building coral Isopora palifera Southern Taiwan, and characterized by using a polyphasic taxonomic approach. Cells of strain were Gram-reaction-negative, aerobic, rod-shaped motile means monopolar flagella formed cream–white colonies. Phylogenetic analyses based on 16S rRNA gene sequences showed that belonged to genus Paracoccus its most closely related neighbours P. aestuarii B7 homiensis DD-R11 marinus KKL-A5 denitrificans...
A bacterial strain, isolated from a sample of reef-building coral (Isopora palifera) collected off the coast southern Taiwan, was characterized using polyphasic taxonomic approach. The designated sw-2(T), Gram-staining-negative, aerobic, rod-shaped and motile, with subpolar flagella, formed greyish pink colonies. Phylogenetic analyses based on 16S rRNA gene sequences indicated that strain sw-2(T) most closely related to Roseivivax halodurans Och 239(T) (97.4 % sequence similarity)...
A bacterial strain designated SW15 T was isolated from a sample of the reef-building coral Isopora palifera , collected in southern Taiwan. The novel characterized using polyphasic taxonomic approach. Cells were Gram-negative, aerobic, light yellow, rod-shaped and motile by means single polar flagellum. In phylogenetic analyses based on 16S rRNA gene sequences, appeared to belong genus Idiomarina class Gammaproteobacteria be most closely related homiensis PO-M2 (97.6 % sequence similarity)....
Genetic variation among populations within plant species can have huge impact on canopy biochemistry and structure across broad spatial scales. Since spectral reflectance is determined largely by structure, be used as a means to capture the variability of th genetic characteristics species. In this study, we measurements Bermuda grass [Cynodon dactylon (L.) Pers.] at both leaf levels characterize traits pertinent phylogeographic along longitudinal latitudinal gradients. An integration...