A5000525972- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Biochemical Analysis and Sensing Techniques
- Sleep and Wakefulness Research
- Neurotransmitter Receptor Influence on Behavior
- Biochemical Acid Research Studies
- Tryptophan and brain disorders
- Cannabis and Cannabinoid Research
- Parasites and Host Interactions
- Marine Bivalve and Aquaculture Studies
- Diet, Metabolism, and Disease
- Hormonal Regulation and Hypertension
- Parasite Biology and Host Interactions
- Lipid metabolism and disorders
- Mollusks and Parasites Studies
- Entomopathogenic Microorganisms in Pest Control
- Neuroscience and Neuropharmacology Research
- Adipokines, Inflammation, and Metabolic Diseases
- Pancreatic function and diabetes
- Parasitic Infections and Diagnostics
- Optical Imaging and Spectroscopy Techniques
- Neuroendocrine regulation and behavior
- Meat and Animal Product Quality
- Neuroscience and Neural Engineering
Columbia University
2021-2025
Université Paris Cité
2016-2023
Centre National de la Recherche Scientifique
2016-2023
Unit of Functional and Adaptive Biology
2017-2023
Ifremer
2022
Center for Environmental Health
2019-2020
Helmholtz Zentrum München
2016-2020
Sorbonne Paris Cité
2016-2019
Florey Institute of Neuroscience and Mental Health
2017
John B. Pierce Laboratory
2017
Current approaches for surveying whole brains neurons activated during a particular state typically rely on immediate early gene (IEG) expression. However, IEG expression is variable across subjects and brain areas, demanding large sample sizes. Further, it cannot determine if the same or different respond to two events. To overcome these issues, we present whole-brain screening method utilizing transgenic mice label at timepoints. An imaging analysis pipeline surveys activity in ~500 areas...
The Pacific cupped oyster Crassostrea gigas is one of the most 'globalized' marine invertebrates and its production predominant in many parts world including Europe. However, it threatened by mortality events associated with pathogenic microorganisms such as virus OsHV-1 bacteria Vibrio aestuarianus. C. also a host for protozoan parasites haplosporidians. In contrast Haplosporidium nelsoni previously detected Europe, H. costale was considered exotic although presence French oysters suggested...
Growing evidence demonstrates the role of striatal dopamine system in regulation glucose metabolism. Treatment with antagonists is associated insulin resistance and hyperglycemia, while agonists are used treatment type 2 diabetes. The mechanism underlying effects metabolism, however not fully understood. Here, we provide mechanistic insights into nucleus accumbens shell (sNAc) dopaminergic signaling systemic metabolism.Endogenous production (EGP), blood mRNA expression lateral hypothalamic...
Ten consanguine monogamous SHR couples (G1) were treated from their 5th to 37th week of age with captopril, 50 mg/-kg/day i.p. Male rats without interruption. Treatment was witheld in female delivery weaning. They compared ten similar which only daily i.p, injected the same volume solvent. Second (G2) generation (untreated) studied. In G1 rats, systolic blood pressure (SBP) and heart weight/body weight (HW/BW) ratio decreased, while rate (HR) not changed. Plasma renin activity remained...
Emerging evidence suggests that energy-dense food alters dopaminergic (DA) transmission in the mesocorticolimbic (MCL) system and can promote development of compulsive-like feeding, reward dysfunction, ultimately weight gain. Yet mechanisms by which metabolic signals influence MCL circuitry to control behavior remain poorly understood. Circulating triglycerides (TG) are a conserved post-prandial signature among mammals high plasma TG associated with reduced responsiveness humans. Here, we...
Six consanguine monogamous SHR couples (G1) were treated from 5 weeks of age on with an alpha blocker, nicergoline, 0.1 mg/kg/day i.p.. Male rats without interruption; treatment was withheld in female delivery to weaning. They compare six similar who only daily i.p. injected the same volume solvent conditions as controls, well naive (untreated) rats. Second (G2) and third (G3) generation studied. In G1 rats, systolic blood pressure (SBP), heart rate, weight/body weight ratio bulbar...
It was not until after World War II that neurochemistry emerged as a distinct discipline in the United States with new technologieschromatography; electrophoresis
Abstract The regulation of food intake, a sine qua non requirement for survival, thoroughly shapes feeding and energy balance by integrating both homeostatic hedonic values food. Unfortunately, the widespread access to palatable has led development habits that are independent from metabolic needs. Among these, binge eating (BE) is characterized uncontrolled voracious eating. While reward deficit seems be major contributor BE, physiological molecular underpinnings BE establishment remain...