Gabriela Garrappa

ORCID: 0000-0001-7557-3872
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Laser Applications in Dentistry and Medicine
  • Assisted Reproductive Technology and Twin Pregnancy
  • Hormonal and reproductive studies
  • CRISPR and Genetic Engineering
  • Selenium in Biological Systems
  • Ovarian function and disorders
  • Comparative Animal Anatomy Studies
  • Cytomegalovirus and herpesvirus research
  • Calcium signaling and nucleotide metabolism
  • Genital Health and Disease

National Agricultural Technology Institute
2019-2024

Universidad de Murcia
2019-2024

Institute for the International Education of Students
2019

Abstract Eggs and embryo manipulation is an important biotechnological challenge to enable positioning, entrapment, selection of reproductive cells advance into a new era nature‐like assisted technologies. Oviductin (OVGP1) abundant protein in the oviduct that binds reversibly zona pellucida, extracellular matrix surrounds eggs embryos. Here, study reports method coupling OVGP1 magnetic nanoparticles (NP) forming complex (NPOv). NPOv specifically embryos reversible manner. Eggs/embryos bound...

10.1002/advs.202306901 article EN cc-by Advanced Science 2024-03-06

Studies of knockout (KO) mice with defects in the endolysosomal two-pore channels (TPCs) have shown TPCs to be involved pathophysiological processes, including heart and muscle function, metabolism, immunity, cancer, viral infection. With objective studying TPC2's roles for first time a large, more humanlike animal model, TPC2 KO pigs were produced using CRISPR-Cas9. A major problem CRISPR-Cas9 edit embryos is mosaicism; thus, we studied effect microinjection timing on mosaicism. Mosaicism...

10.1089/crispr.2020.0078 article EN The CRISPR Journal 2021-02-01

Abstract Boar ejaculate is composed of sperm cells and seminal plasma (SP) emitted in different fractions (pre-sperm fraction; spermatic-rich intermediate post-spermatic fraction), with composition SP volume, which could influence the quality during doses preparation, conservation, interaction female reproductive tract. In artificial insemination (AI) centers, are usually prepared fractions, but inclusion other although controversial, beginning to be applied. The objective was evaluate...

10.1038/s41598-023-42254-3 article EN cc-by Scientific Reports 2023-09-14

Nanotechnology and its applications have advanced significantly in recent decades, contributing to various fields, including reproduction. This study introduces a novel method label porcine oocytes with nanoparticles (NPs) bound oviductin (OVGP1, Ov) for use Assisted Reproductive Technologies (ARTs). Despite promising developments, concerns about NP toxicity gametes necessitate thorough investigation. research aims assess the impact of functionalized NPs (NPOv) on sperm functionality. Boar...

10.1111/rda.14654 article EN cc-by-nc-nd Reproduction in Domestic Animals 2024-10-01

Reproduction, Fertility and Development is an international journal publishing original research , review comment in the fields of reproduction developmental biology humans, domestic animals wildlife

10.1071/rdv35n2ab6 article EN Reproduction Fertility and Development 2022-12-05
Coming Soon ...