- Helicobacter pylori-related gastroenterology studies
- Acute Kidney Injury Research
- Cardiac Arrest and Resuscitation
- Gestational Diabetes Research and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Pregnancy and preeclampsia studies
- Cervical Cancer and HPV Research
- Pediatric health and respiratory diseases
- Birth, Development, and Health
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Nutrition and Health in Aging
- Galectins and Cancer Biology
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Liver Disease Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Cancer Cells and Metastasis
- Liver Disease and Transplantation
- Ovarian function and disorders
- MRI in cancer diagnosis
- Ultrasound in Clinical Applications
- Viral gastroenteritis research and epidemiology
- Peptidase Inhibition and Analysis
- Cardiac and Coronary Surgery Techniques
- Gastric Cancer Management and Outcomes
Nanjing Medical University
2014-2025
Zhejiang Chinese Medical University
2025
Fujian Medical University
2023-2025
Shanghai Children's Medical Center
2023-2025
The First People's Hospital of Shunde
2022-2025
Southern Medical University
2022-2025
Hunan University
2025
The Central Hospital of Shaoyang
2025
Jiangxi Provincial Cancer Hospital
2013-2024
Zhongnan Hospital of Wuhan University
2020-2024
The aim of the study was to evaluate risk factors for long-term mortality and progressive chronic kidney disease (CKD) after cardiac surgery in patients with normal preoperative renal function postoperative acute injury (AKI). From April 2009 December 2012, we prospectively enrolled 3245 our hospital. primary endpoints included survival rates secondary endpoint incidence a follow-up period 2 years. Acute staged by KDIGO classification. Progressive CKD defined as GFR ≤ 30 mL/min/1.73 m2 or...
Nicaragua was the first developing nation to implement routine immunization with pentavalent rotavirus vaccine (RV5). In this RV5-immunized population, understanding infectious etiologies of childhood diarrhea is necessary direct treatment and prevention efforts.We followed a population-based sample children <5 years in León, for episodes through household visits. Information obtained on RV5 history sociodemographics. Stool samples collected during among healthy underwent laboratory analysis...
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication with poor prognosis. In order to identify modifiable perioperative risk factors for AKI, which existing scores are insufficient predict, dynamic clinical score allow clinicians estimate the of CSA-AKI from preoperative early postoperative periods needed.A total 7233 cardiac surgery patients in our institution January 2010 April 2013 were enrolled prospectively and distributed into 2 cohorts. Among derivation...
This study sought to compare the clinical outcomes of upper versus whole-neck prophylactic irradiation in treatment patients with node-negative nasopharyngeal carcinoma (NPC).Between November 2005 and June 2012, 301 NPC were randomly assigned receive primary plus neck (UNI, 153 patients) or (WNI, 148 patients). Patients both groups received tumor nodal regions, WNI group also lower neck. The main endpoint was control rate between 2 groups.With a median follow-up period 39 months (range, 6-84...
Acute kidney injury (AKI) following cardiac surgery is common and associated with poor patient outcomes. Early risk assessment for development of AKI remains a challenge. The combination urinary tissue inhibitor metalloproteinase 2 (TIMP-2) insulin-like growth factor binding protein 7 (IGFBP7) has been shown to be an excellent predictor surgery, but reported studies are predominately non-Asian populations. Adult patients were prospectively enrolled at Zhongshan hospital in Shanghai, China....
Background: The placenta acts not only as a conduit of nutrient and waste exchange between mother developing fetus but also functions regulator the intrauterine environment. Pre-eclampsia (PE) gestational diabetes mellitus (GDM) are leading causes complications during pregnancy. Pathophysiologies show that they associated with one another. Epigenetics provides link environmental factors have previously been linked to poor pregnancy outcomes fetal programming. Methods Results: present study...
Abstract The role of Helicobacter pylori ( H . ) infection in haematological system diseases is not well understood. We conducted this retrospective study to explore the association between and anaemia Chinese population. This was performed Aerospace Center Hospital Beijing. derived data from registration physical population 2012–2016. Logistic regression models were used anaemia. Among 17,791 subjects, there 7,804 (43.9%) subjects with 950 (5.3%) prevalence (+) group significantly higher...
Sarcopenic obesity is associated with several negative health outcomes. However, there are only a few studies on the relationship between SO and metabolic diseases such as diabetes, hypertension, abnormal lipid metabolism in Chinese adults. The aim of this work was to evaluate association adults, explore prediction using relevant anthropometric indicators.All participants underwent questionnaire interview for collection demographic data. Thereafter, they physical examination measurement...
Abstract Objective This study aimed to explore the causal effect of body mass index (BMI) on polycystic ovarian syndrome (PCOS). Methods Genome-wide association data for BMI and PCOS were sourced from Mendelian randomization (MR) base platform. Significantly associated single nucleotide polymorphisms (SNPs) served as instrumental variables in bidirectional 2-sample MR analyses investigate relationship between PCOS. Analytical techniques utilized encompassed inverse variance weighted (IVW)...
AIMTo explore the association between Helicobacter pylori (H.pylori ) infection and obesity/weight gain in a Chinese population. METHODSOur primary outcome was change body mass index (BMI).The generalized linear models were used to H. of BMI, logistic regression obesity. RESULTSA total 3039 subjects recruited analyzed, which 12.8% obese.The prevalence 53.9% (1639/3039) overall 54.6% (212/388) obese subjects.The BMI (+) group not significantly higher than that (-) after adjustment for...
To evaluate the efficacy of using internal jugular vein variability (IJVV) as an index fluid responsiveness in mechanically ventilated patients after cardiac surgery. Seventy were assessed Hemodynamic data coupled with ultrasound evaluation IJVV and inferior vena cava (IVCV) collected calculated at baseline, a passive leg raising (PLR) test 500-ml challenge. Patients divided into volume responders (increase stroke ≥ 15%) non-responders < 15%). We compared differences measured variables...
Although phthalates are common environmental pollutants, few studies have focused on the relationship of exposure with non-alcoholic fatty liver disease (NAFLD) or fibrosis, and especially, alternative been questioned in recent years about whether they better choices. Thus, this study aimed to explore associations major NAFLD fibrosis.Data 1450 adults from National Health Nutrition Examination Survey (NHANES) 2017-2018 were collected. The urinary metabolite concentrations di-2-ethylhexyl...
Introduction Thyroid function has a large impact on humans’ metabolism and is affected by iodine levels, but there scarcity of studies that elucidate the association between thyroid other elements. Methods We performed cross-sectional study 1,067 adults to evaluate associations common essential metals with in living an iodine-adequate area China. Serum free thyroxine (FT4), triiodothyronine (FT3), stimulating hormone (TSH), blood (zinc, iron, copper, magnesium, manganese, calcium) were...
ABSTRACT Background To assess the Knowledge, Attitude, and Practice (KAP) of medical students at Hunan Medicine College towards insomnia TCM treatment. Methods The study included 676 students. More than half were female (64.20%), 33.8% reported experiencing for over a week. Participants' KAP scores evaluated on treatment using scale. Results mean 58.93%, 73.75%, 64.94%, respectively, indicating insufficient knowledge but positive attitudes moderate practices. 78.18%, suggesting better...
Infantile hemangiomas (IHs) are characterized by spontaneous regression, and their pathogenesis involves immune cell infiltration programmed death. The molecular pathways mechanisms involved in pyroptosis IHs still unclear. This study aimed to identify genes related IH regression bioinformatics methods explore the effects of these pyroptosis-related (PRGs) on disease pathology infiltration. microarray dataset GSE127487 was assessed differentially expressed (DEGs) between proliferation-phase...
Abstract Aims The utilization of targeted metabolomics technology promises to facilitate the identification novel metabolic markers in women with gestational diabetes mellitus (GDM), which may turn a more comprehensive investigation underlying mechanisms GDM. Materials and Methods In this study, we used identify serum metabolites from or without differential were categorized analysed using pathway analyses, correlated maternal glucose level, assessed as predictors GDM by receiver operating...
Background Dysthyroid optic neuropathy (DON), the most severe complication of thyroid eye disease (TED), has unclear mechanisms and unsatisfactory treatment outcomes. This study aimed to identify key pathways inflammation-related core genes driving DON progression, potentially informing new therapeutic strategies improving management. Methods Retro-orbital tissues from DON, non-DON TED, healthy controls (HCs) were analyzed using bulk RNA sequencing. Differentially expressed (DEGs) identified...