Lan Liu

ORCID: 0000-0001-7642-6479
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Acute Kidney Injury Research
  • Cardiac Arrest and Resuscitation
  • Gestational Diabetes Research and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pregnancy and preeclampsia studies
  • Cervical Cancer and HPV Research
  • Pediatric health and respiratory diseases
  • Birth, Development, and Health
  • Radiomics and Machine Learning in Medical Imaging
  • Pancreatic and Hepatic Oncology Research
  • Nutrition and Health in Aging
  • Galectins and Cancer Biology
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Liver Disease Diagnosis and Treatment
  • Genetic factors in colorectal cancer
  • Cancer Cells and Metastasis
  • Liver Disease and Transplantation
  • Ovarian function and disorders
  • MRI in cancer diagnosis
  • Ultrasound in Clinical Applications
  • Viral gastroenteritis research and epidemiology
  • Peptidase Inhibition and Analysis
  • Cardiac and Coronary Surgery Techniques
  • Gastric Cancer Management and Outcomes

Nanjing Medical University
2014-2025

Zhejiang Chinese Medical University
2025

Fujian Medical University
2023-2025

Shanghai Children's Medical Center
2023-2025

The First People's Hospital of Shunde
2022-2025

Southern Medical University
2022-2025

Hunan University
2025

The Central Hospital of Shaoyang
2025

Jiangxi Provincial Cancer Hospital
2013-2024

Zhongnan Hospital of Wuhan University
2020-2024

The aim of the study was to evaluate risk factors for long-term mortality and progressive chronic kidney disease (CKD) after cardiac surgery in patients with normal preoperative renal function postoperative acute injury (AKI). From April 2009 December 2012, we prospectively enrolled 3245 our hospital. primary endpoints included survival rates secondary endpoint incidence a follow-up period 2 years. Acute staged by KDIGO classification. Progressive CKD defined as GFR ≤ 30 mL/min/1.73 m2 or...

10.1097/md.0000000000002025 article EN cc-by-nc Medicine 2015-11-01

Nicaragua was the first developing nation to implement routine immunization with pentavalent rotavirus vaccine (RV5). In this RV5-immunized population, understanding infectious etiologies of childhood diarrhea is necessary direct treatment and prevention efforts.We followed a population-based sample children <5 years in León, for episodes through household visits. Information obtained on RV5 history sociodemographics. Stool samples collected during among healthy underwent laboratory analysis...

10.1097/inf.0000000000000427 article EN The Pediatric Infectious Disease Journal 2014-05-30

Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication with poor prognosis. In order to identify modifiable perioperative risk factors for AKI, which existing scores are insufficient predict, dynamic clinical score allow clinicians estimate the of CSA-AKI from preoperative early postoperative periods needed.A total 7233 cardiac surgery patients in our institution January 2010 April 2013 were enrolled prospectively and distributed into 2 cohorts. Among derivation...

10.1161/jaha.116.003754 article EN cc-by-nc-nd Journal of the American Heart Association 2016-08-05

This study sought to compare the clinical outcomes of upper versus whole-neck prophylactic irradiation in treatment patients with node-negative nasopharyngeal carcinoma (NPC).Between November 2005 and June 2012, 301 NPC were randomly assigned receive primary plus neck (UNI, 153 patients) or (WNI, 148 patients). Patients both groups received tumor nodal regions, WNI group also lower neck. The main endpoint was control rate between 2 groups.With a median follow-up period 39 months (range, 6-84...

10.1002/cncr.28201 article EN Cancer 2013-06-13

Acute kidney injury (AKI) following cardiac surgery is common and associated with poor patient outcomes. Early risk assessment for development of AKI remains a challenge. The combination urinary tissue inhibitor metalloproteinase 2 (TIMP-2) insulin-like growth factor binding protein 7 (IGFBP7) has been shown to be an excellent predictor surgery, but reported studies are predominately non-Asian populations. Adult patients were prospectively enrolled at Zhongshan hospital in Shanghai, China....

10.1186/s12882-017-0592-8 article EN cc-by BMC Nephrology 2017-05-30

Background: The placenta acts not only as a conduit of nutrient and waste exchange between mother developing fetus but also functions regulator the intrauterine environment. Pre-eclampsia (PE) gestational diabetes mellitus (GDM) are leading causes complications during pregnancy. Pathophysiologies show that they associated with one another. Epigenetics provides link environmental factors have previously been linked to poor pregnancy outcomes fetal programming. Methods Results: present study...

10.1159/000366386 article EN cc-by-nc Cellular Physiology and Biochemistry 2014-01-01

Abstract The role of Helicobacter pylori ( H . ) infection in haematological system diseases is not well understood. We conducted this retrospective study to explore the association between and anaemia Chinese population. This was performed Aerospace Center Hospital Beijing. derived data from registration physical population 2012–2016. Logistic regression models were used anaemia. Among 17,791 subjects, there 7,804 (43.9%) subjects with 950 (5.3%) prevalence (+) group significantly higher...

10.1038/s41598-017-13955-3 article EN cc-by Scientific Reports 2017-10-12

Sarcopenic obesity is associated with several negative health outcomes. However, there are only a few studies on the relationship between SO and metabolic diseases such as diabetes, hypertension, abnormal lipid metabolism in Chinese adults. The aim of this work was to evaluate association adults, explore prediction using relevant anthropometric indicators.All participants underwent questionnaire interview for collection demographic data. Thereafter, they physical examination measurement...

10.2147/dmso.s308387 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2021-04-01

Abstract Objective This study aimed to explore the causal effect of body mass index (BMI) on polycystic ovarian syndrome (PCOS). Methods Genome-wide association data for BMI and PCOS were sourced from Mendelian randomization (MR) base platform. Significantly associated single nucleotide polymorphisms (SNPs) served as instrumental variables in bidirectional 2-sample MR analyses investigate relationship between PCOS. Analytical techniques utilized encompassed inverse variance weighted (IVW)...

10.1210/clinem/dgae446 article EN publisher-specific-oa The Journal of Clinical Endocrinology & Metabolism 2024-06-29

AIMTo explore the association between Helicobacter pylori (H.pylori ) infection and obesity/weight gain in a Chinese population. METHODSOur primary outcome was change body mass index (BMI).The generalized linear models were used to H. of BMI, logistic regression obesity. RESULTSA total 3039 subjects recruited analyzed, which 12.8% obese.The prevalence 53.9% (1639/3039) overall 54.6% (212/388) obese subjects.The BMI (+) group not significantly higher than that (-) after adjustment for...

10.3748/wjg.v23.i15.2750 article EN cc-by-nc World Journal of Gastroenterology 2017-01-01

To evaluate the efficacy of using internal jugular vein variability (IJVV) as an index fluid responsiveness in mechanically ventilated patients after cardiac surgery. Seventy were assessed Hemodynamic data coupled with ultrasound evaluation IJVV and inferior vena cava (IVCV) collected calculated at baseline, a passive leg raising (PLR) test 500-ml challenge. Patients divided into volume responders (increase stroke ≥ 15%) non-responders < 15%). We compared differences measured variables...

10.1186/s13613-017-0347-5 article EN cc-by Annals of Intensive Care 2018-01-16

Although phthalates are common environmental pollutants, few studies have focused on the relationship of exposure with non-alcoholic fatty liver disease (NAFLD) or fibrosis, and especially, alternative been questioned in recent years about whether they better choices. Thus, this study aimed to explore associations major NAFLD fibrosis.Data 1450 adults from National Health Nutrition Examination Survey (NHANES) 2017-2018 were collected. The urinary metabolite concentrations di-2-ethylhexyl...

10.3389/fnut.2022.1059675 article EN cc-by Frontiers in Nutrition 2022-11-22

Introduction Thyroid function has a large impact on humans’ metabolism and is affected by iodine levels, but there scarcity of studies that elucidate the association between thyroid other elements. Methods We performed cross-sectional study 1,067 adults to evaluate associations common essential metals with in living an iodine-adequate area China. Serum free thyroxine (FT4), triiodothyronine (FT3), stimulating hormone (TSH), blood (zinc, iron, copper, magnesium, manganese, calcium) were...

10.3389/fendo.2023.1134208 article EN cc-by Frontiers in Endocrinology 2023-03-27

ABSTRACT Background To assess the Knowledge, Attitude, and Practice (KAP) of medical students at Hunan Medicine College towards insomnia TCM treatment. Methods The study included 676 students. More than half were female (64.20%), 33.8% reported experiencing for over a week. Participants' KAP scores evaluated on treatment using scale. Results mean 58.93%, 73.75%, 64.94%, respectively, indicating insufficient knowledge but positive attitudes moderate practices. 78.18%, suggesting better...

10.1111/jep.14309 article EN Journal of Evaluation in Clinical Practice 2025-01-13

Infantile hemangiomas (IHs) are characterized by spontaneous regression, and their pathogenesis involves immune cell infiltration programmed death. The molecular pathways mechanisms involved in pyroptosis IHs still unclear. This study aimed to identify genes related IH regression bioinformatics methods explore the effects of these pyroptosis-related (PRGs) on disease pathology infiltration. microarray dataset GSE127487 was assessed differentially expressed (DEGs) between proliferation-phase...

10.2147/ccid.s492535 article EN cc-by-nc Clinical Cosmetic and Investigational Dermatology 2025-01-01

Abstract Aims The utilization of targeted metabolomics technology promises to facilitate the identification novel metabolic markers in women with gestational diabetes mellitus (GDM), which may turn a more comprehensive investigation underlying mechanisms GDM. Materials and Methods In this study, we used identify serum metabolites from or without differential were categorized analysed using pathway analyses, correlated maternal glucose level, assessed as predictors GDM by receiver operating...

10.1111/dom.16213 article EN Diabetes Obesity and Metabolism 2025-01-30

Background Dysthyroid optic neuropathy (DON), the most severe complication of thyroid eye disease (TED), has unclear mechanisms and unsatisfactory treatment outcomes. This study aimed to identify key pathways inflammation-related core genes driving DON progression, potentially informing new therapeutic strategies improving management. Methods Retro-orbital tissues from DON, non-DON TED, healthy controls (HCs) were analyzed using bulk RNA sequencing. Differentially expressed (DEGs) identified...

10.3389/fimmu.2025.1550694 article EN cc-by Frontiers in Immunology 2025-03-12
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