A5101437173- Pregnancy and preeclampsia studies
- Lipid metabolism and biosynthesis
- Cancer-related molecular mechanisms research
- Plant Gene Expression Analysis
- Advanced biosensing and bioanalysis techniques
- Gastrointestinal disorders and treatments
- Biofuel production and bioconversion
- Gastrointestinal Tumor Research and Treatment
- RNA modifications and cancer
- Natural Products and Biological Research
- Diet, Metabolism, and Disease
- Polysaccharides Composition and Applications
- Meat and Animal Product Quality
- Protein Hydrolysis and Bioactive Peptides
- Gastric Cancer Management and Outcomes
- Aquaculture Nutrition and Growth
- Plant pathogens and resistance mechanisms
- Nonmelanoma Skin Cancer Studies
- Congenital Diaphragmatic Hernia Studies
- RNA and protein synthesis mechanisms
- Lignin and Wood Chemistry
- Reproductive System and Pregnancy
- Medical Research and Treatments
- Plant responses to water stress
- Advanced Nanomaterials in Catalysis
Southern Medical University
2020-2025
Nanfang Hospital
2020-2025
Shanghai University of Medicine and Health Sciences
2023-2024
University of Groningen
2024
Southwest University
2017-2023
Nanjing Medical University
2023
Chongqing Academy of Agricultural Sciences
2023
University of Shanghai for Science and Technology
2023
Australian Regenerative Medicine Institute
2023
Monash University
2023
MYB transcription factors are major actors regulating plant development and adaptability. Brassica napus is a staple oil crop hampered by lodging diseases. Here, four B. MYB69 (BnMYB69s) genes were cloned functionally characterized. They dominantly expressed in stems during lignification. BnMYB69 RNA interference (BnMYB69i) plants showed considerable changes morphology, anatomy, metabolism gene expression. Stem diameter, leaves, roots total biomass distinctly larger, but height was...
Objectives The aim of this study is to derive and validate a reliable indicator for predicting an increased risk postoperative mortality in elderly patients undergoing curative resection colorectal cancer (CRC). Design This multicentre retrospective design. Setting participants A total 1227 CRC (age ≥65 years) from three distinct cohorts were enrolled. Participant consisted the derivation (n=845), external validation (n=95) localised (n=287) groups. carcinoembryonic antigen (CEA) lymphocyte...
Arabidopsis thaliana MYB43 (AtMYB43) is suggested to be involved in cell wall lignification. PtrMYB152, the Populus orthologue of AtMYB43, a transcriptional activator lignin biosynthesis and vessel deposition. In this research, genes from Brassica napus (rapeseed) its parental species B. rapa oleracea were molecularly characterized, which dominantly expressed stem other vascular organs showed responsiveness Sclerotinia sclerotiorum infection. The BnMYB43 family was silenced by RNAi,...
In contemporary society, the improper use of antibiotics leads to their persistent presence in ecological environment. Due diverse physical and chemical properties antibiotics, spatial temporal distribution environment varies. Moreover, can stimulate emergence antibiotic resistance genes (ARGs), which complicates monitoring regulation poses a significant threat both aquatic terrestrial environments. This study investigated 15 11 typical ARGs across four categories at 19 sites drinking water...
Membrane lipid chemistry is remarkably different in archaea compared with bacteria and eukaryotes. In the evolutionary context, this also termed divide reflected by distinct biosynthetic pathways. Contemporary organisms have almost without exception only one type of membrane lipid. During early evolution, mixed stages likely occurred, it was hypothesized that instability such mixtures driving force for divide. To examine compatibility between archaeal bacterial lipids, bacterium
Abstract Although DNA 5-hydroxymethylcytosine (5hmC) is recognized as an important epigenetic mark in cancer, its precise role lymph node metastasis remains elusive. In this study, we investigated how 5hmC associates with breast cancer. Accompanying high expression of TET1 and TET2 proteins, large numbers genes the metastasis-positive primary tumors exhibit higher levels than those metastasis-negative tumors. contrast, TET protein decrease significantly within metastatic lesions nodes...
Abstract Background Substantial studies have demonstrated that oxidative stress placenta and endothelial injury are considered to inextricably critical events in the pathogenesis of preeclampsia (PE). Systemic inflammatory response dysfunction induced by circulating factors released from placentae. As a novel biomarker stress, advanced oxidation protein products (AOPPs) levels strongly correlated with PE characteristics. Nevertheless, molecular mechanism underlying effect is still largely...
Objective To investigate the diagnostic value of dermoscopy in defining tumor margin cutaneous squamous cell carcinoma (cSCC) for appropriate surgical margin. Methods A total 90 cSCC patients were enrolled study. All recruited into two groups: those who preserved intact macroscopic features neoplasms without or after incisional biopsy and with uncertain residual tumors excisional biopsy. dermoscopy-defined 8mm outward was used according to boundaries observed naked eye dermoscopy. excised...
Colorectal cancer (CRC) is one of the most common tumor types digestive tract. Its incidence and mortality rates are among highest all gastrointestinal types. The expression leucine zipper downregulated in 1 (LDOC1) decreased numerous In present study, aim was to investigate role LDOC1 determine potential molecular mechanisms its action CRC. CRC tissues adjacent normal detected by reverse transcription‑quantitative polymerase chain reaction immunohistochemistry. four cell lines, compared...
Sclerotinia sclerotiorum (Ss) is a devastating fungal pathogen that causes stem rot in rapeseed (Brassica napus), and also detrimental to mulberry many other crops. A wild germplasm, Morus laevigata, showed high resistance Ss, but the molecular basis for largely unknown. Here, transcriptome response characteristics of M. laevigata Ss infection were revealed by RNA-seq. total 833 differentially expressed genes (DEGs) detected after inoculation leaf laevigata. After GO terms KEGG pathways...
Abstract In this study, an electrochemical biosensor was constructed for the detection of fibrin, specifically by a simple two‐step approach, with novel artificial enzyme (Tetrazyme) based on DNA tetrahedral framework as signal probe. The multichannel screen‐printed electrode activated surface cannot only remove some biological impurities, but also serve carrier to immobilize large number antigen proteins. nanostructure employed ensure high sensitivity probe analysis. hemin chimeric into...
Detection of microRNA-196a (miRNA-196a) is crucial in cancer research, enabling early diagnosis and providing guidance for individualized treatment. In this work, we employed a naturally occurring negatively charged nano silk fibroin (NSF) with high mechanical properties, biocompatibility, conductivity to be encapsulated positively gold nanoparticles (AuNPs) were used as film-forming materials electrostatic layer-by-layer self-assembly modify the working electrode screen-printed carbon...