A5045473392- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Neuroendocrine Tumor Research Advances
- Chronic Lymphocytic Leukemia Research
- Tumors and Oncological Cases
- Oral and Maxillofacial Pathology
- Cardiac Structural Anomalies and Repair
- Alcohol Consumption and Health Effects
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Neuroblastoma Research and Treatments
- Pericarditis and Cardiac Tamponade
- Histiocytic Disorders and Treatments
- Substance Abuse Treatment and Outcomes
- Developmental Biology and Gene Regulation
- Lymphoma Diagnosis and Treatment
- Cannabis and Cannabinoid Research
- RNA Research and Splicing
- Takotsubo Cardiomyopathy and Associated Phenomena
- Neurofibromatosis and Schwannoma Cases
- Bone Tumor Diagnosis and Treatments
- Vascular Tumors and Angiosarcomas
Temple University Hospital
2018-2025
St. Jude Children's Research Hospital
2024-2025
Hospital of the University of Pennsylvania
2023-2025
University of Pennsylvania
2024
The University of Texas of the Permian Basin
2020-2023
Texas Tech University Health Sciences Center
2020-2023
Texas Tech University
2020-2023
University of Leeds
2023
Cincinnati Children's Hospital Medical Center
2023
University of Tennessee Health Science Center
2019-2022
Shotgun metagenomic analysis of the human associated microbiome provides a rich set microbial features for prediction and biomarker discovery in context diseases health conditions. However, use such high-resolution presents new challenges, validated computational tools learning tasks are lacking. Moreover, classification rules have scarcely been independent studies, posing questions about generality generalization disease-predictive models across cohorts. In this paper, we comprehensively...
The increasing COVID-19 cases in the USA have led to overburdening of healthcare regard invasive mechanical ventilation (IMV) utilization as well mortality. We aim identify risk factors associated with poor outcomes (IMV and mortality) hospitalized patients. A meta-analysis observational studies epidemiological characteristics PubMed, Web Science, Scopus, medRxiv from December 1, 2019 May 31, 2020 following MOOSE guidelines was conducted. Twenty-nine full-text detailing characteristics,...
Glucose transporter 1 (GLUT1) is a sensitive immunohistochemical marker for perineural cells and certain mesenchymal neoplasms, including chordoma, desmoplastic small round cell tumor, desmoid-type fibromatosis, epithelioid sarcoma, gastrointestinal stromal myoepithelioma, schwannoma, undifferentiated pleomorphic sarcoma. In this study, we focus on the morphological challenges in differentiating between ganglion cysts perineuriomas. To our knowledge, no previous studies have explored...
Breast self-examination is a screening method used in an attempt to detect breast cancer. The involves the woman herself observing and feeling each for possible lumps, distortions or swelling. self -examination recommended because it safe, easy, feasible, private, painless require no specific equipment. self- examination plays important role preventing cancer by using standard guidelines. Objectives: Current study was designed evaluate nurse’s knowledge practice of BSE order decrease...
Heart failure (HF) is a complex and potentially life-threatening medical condition posing significant risks to individuals. It associated with substantial health care expenditures, considerable morbidity mortality, decline in functional capacity quality of life. Cardiac contractility modulation (CCM) has emerged as promising device-based treatment for patients HF reduced ejection fraction (HFrEF). Studies have shown that CCM HFrEF can improve exercise tolerance life reduce hospitalizations....
Heparin resistance can be defined as high doses of unfractionated heparin (UFH), greater than 35,000 IU/day, required to raise the activated partial thromboplastin time (aPTT) and coagulation (ACT) within therapeutically desired ranges or impossibility doing so. The most common pathology responsible is deficiency anti-thrombin III (ATIII) deficiency. Other clinically relevant conditions that present with are congenital deficiencies; use during extracorporeal circulation, asparaginase therapy...
We present curatedMetagenomicData, a Bioconductor and command-line interface to thousands of metagenomic profiles from the Human Microbiome Project other publicly available datasets, ExperimentHub, platform for convenient cloud-based distribution data R desktop. The resource provides standardized per-participant metadata linked bacterial, fungal, archaeal, viral taxonomic abundances, as well quantitative metabolic functional profiles. datasets can be immediately analyzed in or software with...
Despite a growing appreciation for microglial influences on the developing brain, responsiveness of microglia to insults during gestation remains less well characterized, especially in embryo when themselves are still maturing. Here, we asked if fetal could coordinate an innate immune response exogenous insult. Using time-lapse imaging, showed that hypothalamic actively surveyed their environment by near-constant "touching" radial glia projections. However, following insult (i.e., IUE or AAV...
Islet-1 (ISL1) plays key roles in programming the epigenome and facilitating recruitment of additional regulatory factors. Although it has been used as a marker for pancreatic neuroendocrine tumors (PanNETs), ISL1 reactivity other tumor types are critically missing. immunohistochemistry was performed on 147 (NET) originated pancreas, gastrointestinal tract, lung, thyroid, parathyroid, pituitary, adrenal medulla, head/neck, genitourinary skin; 110 non-neuroendocrine thymus, mesothelium,...
Posterior reversible encephalopathy syndrome (PRES) is an increasingly recognizable neuro-clinical syndrome. Clinical and neurological manifestations of PRES include hypertension, headache, encephalopathy, seizures, symmetrical white matter changes on brain MRI. Most common precipitants are acute medical illness, hypertensive crisis, eclampsia, immunosuppressive therapy, chemotherapy. Bevacizumab a monoclonal antibody that halts angiogenesis by inhibiting vascular endothelial growth factor....
Several morphologically overlapping (myo)fibroblastic neoplasms harbour USP6 fusions, including aneurysmal bone cysts, nodular fasciitis, myositis ossificans, cranial fibro-osseous pseudotumour of the digits, and cellular fibroma tendon sheath. USP6-induced are almost universally benign cured by local excision. We aim to highlight diagnostic value fusion detection in a series aggressive-appearing paediatric myofibroblastic tumours.Three deep-seated, radiographically aggressive, rapidly...
Problem: Systems-based practice focuses on the organization, financing, and delivery of medical services. The American Association Medical Colleges has recommended that systems-based be incorporated into schools' curricula. However, experiential learning in practice, including practical strategies to improve quality efficiency clinical care, is often absent from or inconsistently included education. Intervention: A multidisciplinary clinician nonclinician faculty team partnered with a...
One-third of gastrointestinal stromal tumors (GISTs) that lack KIT or PDGFRA mutations show succinate dehydrogenase (SDH) promoter hypermethylation. Most SDH-deficient GISTs occur in the pediatric, adolescent, young adult setting and have unique features including predilection for stomach, multinodular plexiform architecture, epithelioid cytology, prominence lymphovascular invasion, nodal metastasis. Dedifferentiation GIST is a rare histologic change which may de novo secondary to imatinib...
Systemic lupus erythematous (SLE) is frequently encountered in clinical practice; a widespread immunological response can involve any organ system, sometimes leading to rare and diagnostically challenging presentations. We describe 38-year-old female who presented with symmetric numbness tingling of the hands feet, cervical pain. Imaging studies were not diagnostic serious underlying pathology. The patient developed ascending paresis involving lower extremities cranial muscles (dysphagia...