- Cardiac, Anesthesia and Surgical Outcomes
- Esophageal Cancer Research and Treatment
- Enhanced Recovery After Surgery
- Lung Cancer Diagnosis and Treatment
- Anesthesia and Pain Management
- Shoulder and Clavicle Injuries
- Tracheal and airway disorders
- Delphi Technique in Research
- Airway Management and Intubation Techniques
- Gastric Cancer Management and Outcomes
- Anesthesia and Sedative Agents
- Nausea and vomiting management
- Trauma Management and Diagnosis
- Mobile Health and mHealth Applications
- Music Therapy and Health
- Esophageal and GI Pathology
- Surgical Simulation and Training
- Pain Management and Opioid Use
- Traumatic Ocular and Foreign Body Injuries
- Aortic aneurysm repair treatments
- Pituitary Gland Disorders and Treatments
- Metastasis and carcinoma case studies
- Gallbladder and Bile Duct Disorders
- Parathyroid Disorders and Treatments
- Innovations in Medical Education
University Medical Center Utrecht
2018-2025
Utrecht University
2021-2025
University of Amsterdam
2024
Amsterdam University Medical Centers
2024
University Health Network
2023
Toronto General Hospital Research Institute
2023
University of Toronto
2023
Toronto General Hospital
2023
Importance Current fasting guidelines for procedures under anesthesia are poorly implemented, leading to negative metabolic sequelae. Recent studies in children showed support of liberal clear fluid intake; adult physiology can intake, but implementation lacking. Objective To evaluate the successfulness a policy with regard duration, well-being, and safety adults scheduled anesthesia. Design, Setting, Participants This was quality improvement study conducted from January 2016 July 2021 at...
Major surgery is associated with negative postoperative outcomes such as complications and delayed or poor recovery. Multimodal prehabilitation can help to reduce the effects of major surgery. Offering by means mobile health (mHealth) could be an effective new approach.The objectives this pilot study were (1) evaluate usability Be Prepared mHealth app prototype for people undergoing surgery, (2) explore whether was capable bringing about a change in risk behaviors, (3) estimate preliminary...
Corticosteroids are prescribed commonly to patients with autoimmune or pulmonary diseases, post-transplant and neurosurgery, as well adrenal insufficiency [1, 2]. These at risk of tertiary gland insufficiency, for which supplementation corticosteroids during stress, such surgery, is advised [3, 4]. The Peri-operative Replacement Exogenous Steroids (PREdS) study performed an audit compliance guidelines supplemental in possible the UK [5]. A total 21,411 adult undergoing surgery under care...
Abstract Background Thoracic epidural analgesia is the standard postoperative pain management strategy in esophageal cancer surgery. However, paravertebral block may achieve comparable control while inducing less side effects, which be beneficial for recovery. This study primarily aims to compare quality of recovery between catheter versus thoracic patients undergoing minimally invasive esophagectomy. Methods represents a randomized controlled superiority trial. A total 192 will 4 Dutch...
SUMMARY Adequate postoperative pain management is essential to facilitate uneventful recovery after esophagectomy. Although epidural analgesia the gold standard, it not satisfactory in all patients. The aim of this study describe efficacy and complication profile minimally invasive esophagectomy (MIE). A total 108 patients who underwent a robot-assisted (McKeown) MIE for esophageal cancer were included from single center prospective database (2012–2015). number that could receive analgesia,...
Adequate pain control is essential in the treatment of patients with traumatic rib fractures. Although epidural analgesia recommended international guidelines, use remains debatable and not undisputed. The aim this study was to describe efficacy safety multiple A retrospective cohort performed. Patients ≥3 fractures following blunt chest trauma who received between January 2015 2018 were included. main outcome parameters success rate incidence medication-related side effects catheter-related...
Abstract The aim of this study was to evaluate the surgical treatment esophago-tracheobronchial fistulas (ETBFs) that occurred after esophagectomy with gastric conduit reconstruction in a tertiary referral center for esophageal surgery. All patients who underwent repair an ETBF were included center. primary outcome successful recovery ETBF, defined as patent airway at 90 days fistula repair. Secondary outcomes details on clinical presentation, diagnostics, and postoperative course Between...
Abstract Background Functional capacity is used as an indicator for cardiac testing before non-cardiac surgery and often performed subjectively. However, the value of subjectively estimated functional in predicting complications under debate. We determined predictive assessed on postoperative mortality. Design An observational cohort study patients aged 60 years over undergoing elective inpatient a tertiary referral hospital. Methods Subjective was by anaesthesiologists. The primary outcome...
Laparoscopic gastrectomy could reduce pain and opioid consumption, compared to open gastrectomy. However, it is difficult judge the clinical relevance of this reduction, since these outcomes are reported in few randomized trials limited detail. This secondary analysis a multicenter trial laparoscopic versus for resectable gastric adenocarcinoma (cT1-4aN0-3bM0). Postoperative was analyzed by consumption oral morphine equivalents (OME, mg/day) at postoperative day (POD) 1–5, WHO analgesic...
Objective: To compare quality of recovery in patients receiving epidural or paravertebral analgesia for minimally invasive esophagectomy (MIE). Summary Background Data: Paravertebral may be a promising alternative to analgesia, avoiding potential side effects and improving postoperative recovery. Methods: This randomized controlled superiority trial was conducted across four Dutch centers with esophageal cancer scheduled transthoracic MIE intrathoracic anastomosis, randomizing receive either...
Abstract Background Thoracic epidural analgesia has been the mainstay for pain control in esophageal cancer patients undergoing minimally invasive esophagectomy (MIE). Although effective potentially contributes to achieving enhanced recovery after surgery (ERAS) goals MIE, it can have counterproductive side effects such as hypotension, urinary retention and reduced mobility. Paravertebral may be a promising alternative analgesia, avoiding potential improving postoperative recovery. Methods...
With the increasing complexity and prolonged duration of endoscopic retrograde cholangiopancreatography (ERCP) procedures, sedation shifted from conscious with benzodiazepines to deep propofol. We assessed technical success adverse event rates ERCP versus sedation.
Although elective surgery is generally safe, some procedures remain associated with an increased risk of complications. Improved preoperative stratification and earlier recognition these complications may ameliorate postoperative recovery improve long-term outcomes. The perioperative longitudinal study outcomes (PLUTO) cohort aims to establish a comprehensive biorepository that will facilitate research in this field. In profile paper, we discuss its design rationale opportunities for future...
Abstract Background Adequate postoperative pain management is essential to facilitate uneventful recovery after esophagectomy. Although epidural analgesia the gold standard, it not satisfactory in all patients. The aim of this study was describe efficacy and complication profile minimally invasive esophagectomy (MIE). Methods A total 108 patients who underwent a robot-assisted (McKeown) MIE for esophageal cancer were included from single center prospective database (2012–2015). number that...
<sec> <title>BACKGROUND</title> Major surgery is associated with negative postoperative outcomes such as complications and delayed or poor recovery. Multimodal prehabilitation can help to reduce the effects of major surgery. Offering by means mobile health (mHealth) could be an effective new approach. </sec> <title>OBJECTIVE</title> The objectives this pilot study were (1) evaluate usability Be Prepared mHealth app prototype for people undergoing surgery, (2) explore whether was capable...