Norin Ahmed
A5072093341- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Microscopic Colitis
- Inflammatory Bowel Disease
- Venous Thromboembolism Diagnosis and Management
- Mental Health Research Topics
- Meta-analysis and systematic reviews
- Diagnosis and treatment of tuberculosis
- Liver Disease and Transplantation
- Intracerebral and Subarachnoid Hemorrhage Research
- Health Policy Implementation Science
- Statistical Methods in Clinical Trials
- Liver Disease Diagnosis and Treatment
- Intestinal Malrotation and Obstruction Disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Gastrointestinal disorders and treatments
- Treatment of Major Depression
- Hepatitis Viruses Studies and Epidemiology
University College London
2021-2025
MRC Clinical Trials Unit at UCL
2022-2025
Faculty (United Kingdom)
2021
Rationale Atrial fibrillation causes one-fifth of ischemic strokes, with a high risk early recurrence. Although long-term anticoagulation is highly effective for stroke prevention in atrial fibrillation, initiation after usually delayed by concerns over intracranial hemorrhage risk. Direct oral anticoagulants offer significantly lower than other anticoagulants, potentially allowing earlier and recurrence, but the safety efficacy this approach has not been established. Aim Optimal timing...
The optimal timing of anticoagulation for patients with acute ischaemic stoke atrial fibrillation is uncertain. We investigated the efficacy and safety early compared delayed initiation direct oral anticoagulants (DOACs) in stroke associated fibrillation.
Abstract Objectives Predicting longer term response to biological therapy for small bowel Crohn’s disease (SBCD) is an unmet clinical need. Diffusion-weighted MR imaging (DWI) may indicate activity, but its predictive ability, if any, unknown. We investigated the prognostic value of DWI one year or remission (RoR) in SBCD patients commencing biologic therapy, including incremental over C-reactive protein (CRP) and faecal calprotectin (FC). Methods A subset participants a prospective,...
Abstract Background Atrial fibrillation causes one-fifth of ischaemic strokes, with a high risk early recurrence. Although long-term anticoagulation is highly effective for stroke prevention in atrial fibrillation, initiation after can be delayed by concerns over intracranial haemorrhage risk. Direct oral anticoagulants offer significantly lower than other anticoagulants, potentially allowing earlier and recurrence, but the safety efficacy this approach has not been established. This article...
Abstract Background Small bowel Crohn’s disease (SBCD) is increasingly treated with biological therapies. Predicting response or remission (RoR) for individual patients difficult and complicates treatment strategy. We aimed to determine if motility magnetic resonance imaging (mMRI) superior CRP fecal calprotectin (FC) the prediction of RoR at 1 year in commencing biologics SBCD. Methods Prospective, multicenter (n = 13) cohort study active non-stricturing SBCD requiring anti-TNFα...
Abstract Objectives Altered body fat and muscle mass in Crohn’s disease (CD) have been linked to adverse course outcomes. Prediction of treatment response or remission (RoR) small bowel CD (SBCD) biologic therapy remains challenging. We aimed establish the prognostic value composition parameters measured using MR enterography (MRE) for RoR at 1 year patients with SBCD commencing therapy. Methods Participants were identified from those recruited a prospective, multicentre study investigating...
Bacterial infection is a major cause of mortality in patients with cirrhosis. Spontaneous bacterial peritonitis (SBP) serious and common cirrhosis ascites. Secondary prophylactic antibiotic therapy has been shown to improve outcomes after an episode SBP but primary prophylaxis prevent the first remains contentious. The aim this trial assess whether co-trimoxazole improves overall survival compared placebo adults ascites.The ASEPTIC multicentre, placebo-controlled, double-blinded, randomised...
Abstract Objective To improve communication of harm in publications randomised controlled trials via the development recommendations for visually presenting outcomes. Design Consensus study. Setting 15 clinical units registered with UK Clinical Research Collaboration, an academic population health department, Roche Products, and The BMJ . Participants Experts trials: 20 statisticians, one industry statistician, economist, data graphics designer, two clinicians. Main outcome measures A...
Abstract Background According to the cognitive neuropsychological model, antidepressants reduce symptoms of depression and anxiety by increasing positive relative negative information processing. Most studies whether alter emotional processing use small samples healthy individuals, which lead low statistical power selection bias are difficult generalise clinical practice. We tested selective serotonin reuptake inhibitor (SSRI) sertraline altered recall in a large randomised controlled trial...