- Spine and Intervertebral Disc Pathology
- Advanced X-ray and CT Imaging
- Orthopedic Surgery and Rehabilitation
- Hepatocellular Carcinoma Treatment and Prognosis
- Peripheral Nerve Disorders
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Advanced MRI Techniques and Applications
- Spinal Fractures and Fixation Techniques
- Shoulder Injury and Treatment
- Medical Imaging and Analysis
- Aortic Disease and Treatment Approaches
- Phytochemicals and Antioxidant Activities
- Gallbladder and Bile Duct Disorders
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Bone and Joint Diseases
- Elbow and Forearm Trauma Treatment
- Pancreatitis Pathology and Treatment
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal pain and rehabilitation
- Liver Disease Diagnosis and Treatment
- Lower Extremity Biomechanics and Pathologies
- Radiomics and Machine Learning in Medical Imaging
- Biochemical and Structural Characterization
National Cheng Kung University Hospital
2016-2025
National Cheng Kung University
2012-2024
Focaltech Systems (Taiwan)
2021
Asia University
2008-2020
WuFeng University
2020
Tzu Chi University
2018
Hualien Tzu Chi Medical Center
2018
Fujian Agriculture and Forestry University
2017
Central Taiwan University of Science and Technology
2015
Asia University
2009
Purpose To assess the use of dual-energy computed tomographic (CT) virtual noncalcium technique in evaluation bone marrow edema vertebral compression fractures. Materials and Methods This prospective study was approved by institutional review board; informed consent obtained from all patients. Sixty-three consecutive patients with 112 thoracic and/or lumbar fractures were studied between January 2011 April 2012. All underwent both CT (100 kV Sn140 kV, where Sn indicates a 0.4-mm tin filter)...
To determine if in vivo detection of choline by using hydrogen 1 (1H) magnetic resonance (MR) spectroscopy with dynamic contrast material-enhanced MR imaging can help differentiate between benign and malignant musculoskeletal tumors.MR was performed 36 consecutive patients bone soft-tissue tumors larger than 1.5 cm diameter. Examinations were at T a surface coil appropriate for the location lesions. Single-voxel 1H point-resolved spectroscopic sequence echo times 40, 135, 270 msec. The...
The calibration of a catheter‐based system to be used for therapeutic radiation treatment prevent restenosis following interventional coronary procedures is described. primary dosimetry was performed ionometrically using an extrapolation chamber equipped with 1‐mm diameter collecting electrode measure absorbed dose in tissue equivalent plastic at depth 2 mm. These results are compared measurements radiochromic dye film, which also characterize sources axial and trans‐axial uniformity,...
It has been unclear to which antimicrobial activities (e.g., anti-gram-positive bacterial, anti-gram-negative antifungal, antiparasitic, and antiviral activities) of peptides (AMPs) a given physiochemical property matters most. This is the first computational study using large-scale AMPs examine relationships between two major properties AMPs-amphipathicity net charge. The results showed that among all kinds activities, amphipathicity charge best differentiated with without bacterial...
To assess the effect of transarterial embolization (TAE) for adhesive capsulitis (AC) by evaluating clinical outcomes and changes in inflammation using magnetic resonance imaging (MRI). Patients who had undergone TAE between August 2020 2023 AC refractory to conservative treatments without any invasive procedures more than 3 months, baseline 3-month post-AC follow-up contrast-enhanced MRI evaluations, were included. A suspension mixture 500 mg imipenem/cilastatin 10 mL iodinated contrast...
Purpose To assess the use of dual-energy computed tomographic (CT) virtual noncalcium technique in evaluation bone marrow edema vertebral compression fractures. Materials and Methods This prospective study was approved by institutional review board; informed consent obtained from all patients. Sixty-three consecutive patients with 112 thoracic and/or lumbar fractures were studied between January 2011 April 2012. All underwent both CT (100 kV Sn140 kV, where Sn indicates a 0.4-mm tin filter)...
Objective: To retrospectively compare treatment of hepatocellular carcinoma (HCC) with transarterial chemoembolization (TACE) using gelatin sponges or microspheres plus lipiodol-doxorubicin vs. doxorubicin-loaded drug-eluting beads (DEB).Materials and Methods: A total 158 patients HCC received TACE from November 2010 to 2011 were enrolled in this study, including 64 (40.5%) (group A), 41 (25.9%) B), 53 (33.5%) DEB C).Tumor response adverse events (AEs) evaluated.Results: No significant...
Currently, no standard of care or therapies have been established for patients with advanced HCC. We evaluated the efficacy and safety conventional transarterial chemoembolization using gelatin sponges microspheres plus lipiodol-doxorubicin (cTACE) TACE doxorubicin-loaded drug eluting beads (DEB-TACE).This retrospective study included 273 who received cTACE (n = 201) DEB-TACE. Tumor response, survival, adverse events were over a 5-year follow-up period.During follow-up, greater percentage...
In this study, we modified the previously proposed X2CT-GAN to build a 2Dto3D-GAN of spine. This study also incorporated radiologist's perspective in adjustment input signals prove feasibility automatic production three-dimensional (3D) structures spine from simulated bi-planar two-dimensional (2D) X-ray images. Data 1012 computed tomography (CT) studies 984 patients were retrospectively collected. We tested model under different dataset sizes (333, 666, and 1012) with bone signal conditions...
PURPOSE: To evaluate the usefulness of magnetic resonance (MR) cholangiography in excluding biliary atresia as cause neonatal cholestasis. MATERIALS AND METHODS: MR was performed on 10 control and 16 jaundiced neonates infants aged 3 days to 5 months. Diagnosis (n = 6) confirmed with surgery liver biopsy, or without surgical cholangiography. hepatitis 9) clinical follow-up until jaundice resolved. In one infant, paucity intrahepatic ducts diagnosed at biopsy. respiratory-triggered, heavily...
Antimicrobial peptides (AMPs) are potent drug candidates against microbes such as bacteria, fungi, parasites, and viruses. The size of AMPs ranges from less than ten to hundreds amino acids. Often only a few acids or the critical regions antimicrobial proteins matter functionality. Accurately predicting AMP could benefit experimental designs. However, no extensive analyses have been done specifically on computational modeling them is either non-existent settled other problems. With focus...
IscR, an Fe–S cluster-containing transcriptional factor, regulates genes involved in various cellular processes. In response to environmental stimuli such as oxidative stress and iron levels, IscR switches between its holo apo forms regulate targets. binding sequences are classified into two types: the type 1 box that is specific for holo-IscR binding, 2 binds holo- apo-IscR. Studying Klebsiella pneumoniae CG43S3, we have previously shown availability capsular polysaccharide (CPS)...
Summary The effects of blanching, drying and extraction processes on the antioxidant activities one kind Taiwanese yam peel, Darsan ( Dioscorea alata ), were investigated. measurements included total phenolic content, reducing power α ,α‐diphenyl‐β‐pricryl‐hydrazyl (DPPH) radical‐scavenging activity. 50% ethanolic, hot water extracts from peel all had much higher than those flesh. Among three methods, ethanolic resulted in highest while was more appropriate for Blanching by immersing 85 °C...
<i>Background:</i> The administration of memantine, an N-methyl-<i>D</i>-aspartate (NMDA) receptor antagonist, has clinically improved the cognitive function patients with Alzheimer’s disease (AD), indicating that a disturbance in glutamatergic transmission might be involved predisposition to developing disease. <i>Aim:</i> potential association polymorphisms NMDA subunits NR3A and NR3B, encoded by <i>GRIN3A</i> and<i> GRIN3B</i>...
Solanum lyratum Thunberg (Solanaceae) has been used as a folk medicine for treating liver, lung and esophagus in the Chinese population. Our previous studies have shown that crude extract of S. (SLE) induced apoptosis colo 205 human colon adenocarcinoma cells; however, there is no report to show SLE affect immune responses vivo. In this study, vivo effects on leukemia WEHI-3 cells such phagocytosis natural killer (NK) cell activity normal mice were investigated. The treatment decreases...
changes may occur in tumor phenotype and receptor status during the progression of breast cancer. Discordance between primary metastases has implications for further treatment prognosis. 185 patients confirmed cancer metastasis were retrospectively analyzed 1999–2019. All pathological assessments receptors phenotypes both primaries recorded. rates discordance 18.65%, 30.57%, 16.06% ER, PR, HER2, respectively 31.62% change. Patients with ER experienced a worse OS PMS, those loss had PMS...