Michal Laufer‐Perl

ORCID: 0000-0001-9105-2559
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Cardiac Imaging and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Effects of Exercise
  • Heart Failure Treatment and Management
  • Cardiac Valve Diseases and Treatments
  • Acute Myocardial Infarction Research
  • Viral Infections and Immunology Research
  • Ultrasound in Clinical Applications
  • Pericarditis and Cardiac Tamponade
  • CAR-T cell therapy research
  • Peptidase Inhibition and Analysis
  • Cardiac pacing and defibrillation studies
  • Cardiac tumors and thrombi
  • COVID-19 Clinical Research Studies
  • Cardiomyopathy and Myosin Studies
  • Melanoma and MAPK Pathways
  • Cardiovascular Disease and Adiposity
  • Cancer Treatment and Pharmacology
  • Cardiac Arrhythmias and Treatments
  • Long-Term Effects of COVID-19
  • Phonocardiography and Auscultation Techniques
  • Heart Rate Variability and Autonomic Control

Tel Aviv Sourasky Medical Center
2015-2025

Tel Aviv University
2014-2024

Institute of Cardiology
2021

Gregg W. Stone JoAnn Lindenfeld Josep Rodés‐Cabau Stefan D. Anker Michael R. Zile and 95 more Saibal Kar Richard Holcomb Michael Pfeiffer Antoni Bayés‐Genís Jeroen J. Bax Alan J. Bank Maria Rosa Costanzo Stefan Verheye Ariel Roguin Gerasimos Filippatos Julio Núñez Elizabeth C. Lee Michal Laufer‐Perl Gil Moravsky Sheldon E. Litwin Edgard A. Prihadi Hemal Gada Eugene S. Chung Matthew J. Price Vinay Thohan Dimitry Schewel Sachin Kumar Stephan Kische Kevin Shah Daniel J. Donovan Yiran Zhang Neal Eigler William T. Abraham John Gorcsan Marrick Kukin Kunjan Bhatt David Shavelle Liviu Klein Alicia Del Carmen Becerra Romero Garrie J. Haas Vijay Swarup Elizabeth Volz F. Collado Amit Badiye Luanda Grazette Michelle Hamilton Tom McRae Sumant Lamba Steven K. Krueger Timothy Byrne Leslie A. Miller Youssef Al-Saghir Robin Chand David Shavelle Saeb F. Khoury Ira Dauber Sula Mazimba Suneet Mittal Steven Driver Stanislav Weiner Samir Kapadia Priyanka Gosain Rajeev Singh Zvonimir Krejcer Lynn Punnoose Stuart Russell Maria Karas Gautam Kumar Ajith Nair Robert Widmer Ramesh Kundur Nabil Dib Ugochukwu Egolum Miguel Alvarez Villela John Boehmer George Petrossian Jeffrey Teuteberg Peter Bittenbender Ignacio J. Amat‐Santos Ana Maria Garcı́a María Del Trigo S. Mirabet Luis Nombela‐Franco Domingo A. Pascual‐Figal Israel Gotsman Wadi Kinany Sorel Goland Dov Freimark Tal Hasin Oren Caspi Eli I. Lev Hilmi Alnsasra Burkhard Sievers Mohammad Sherif Karl Fengler Rolf Wachter Ince Hüseyin Jörg Hausleiter Ralf Stephan Von Bardeleben Ince Hüseyin

An interatrial shunt may provide an autoregulatory mechanism to decrease left atrial pressure and improve heart failure (HF) symptoms prognosis.

10.1161/circulationaha.124.070870 article EN Circulation 2024-09-23
Charlotte Fenioux Baptiste Abbar Samia Boussouar Marie Bretagne John R. Power and 95 more Javid J. Moslehi Paul Gougis Damien Amelin Agnès Dechartres Lorenz Lehmann Pierre‐Yves Courand Jennifer Cautela Joachim Alexandre Adrien Procureur Antoine Rozes Sarah Léonard-Louis Juan Qin Nausheen Akhter Nazanin Aghel Kingsley Amidi Élizabeth Anderson Dimitri Arangalage Mandar A. Aras Aarti Asnani Lauren A. Baldassarre Rocio Barovila Ana Sofia Barroso Wendy Bottinor Anissa Bouali Eve Cariou Wei‐Ting Chang Richard K. Cheng Shanthini M. Crusz Anita Deswal Pierre‐Yves Dietrich Grace K. Dy Clémence Docq Steven M. Ewer Suran L. Fernando Danette L. Flint Roberta Florido Satoshi Fukushima Elena Galli Elizabeth Gaughan Manhal Habib Andrew Haydon Lucie Heinzerling Osnat Itzhaki Ben Zadok N. Issa Anja Karlstaedt Kazuo Kitagawa Michael Layoun Michal Laufer‐Perl Carrie Lenneman Darryl P. Leong Chloé Lesiuk Joshua Levenson Teresa López‐Fernández Yan Liu Kristen Machado Pedro Moliner Ryota Morimoto Michel Obéid Anna Narezkina Nicolas L. Palaskas Giovanni Peretto Nicolas Piriou Juan Carlos Plana Peter P. Rainer Maxime Robert‐Halabi Fanny Rocher Eugenia Rota François Roubille Theresa Ruf Shahneen Sandhu Francis Sanjeev Nobuhiko Seki Kazuko Tajiri Yuichi Tamura Franck Thuny Romain Trésorier Isik Turker Ellen Warner Vlad G. Zaha Han Zhu Rémi Cheynier Bénédicte Charmeteau-De Muylder Alban Redheuil Florence Tubach Jacquès Cadranel Audrey Milon Stéphane Éderhy Thomas Similowski Douglas B. Johnson Ian Pizzo Toniemarie Catalan Olivier Benveniste Salim S. Hayek Yves Allenbach Michèlle Rosenzwajg

10.1038/s41591-023-02591-2 article EN Nature Medicine 2023-10-26

Abstract Background Immune checkpoint inhibitors (ICIs) have revolutionized the prognosis of cancer. Diabetes mellitus (DM) has been shown to a negative effect on patients treated with ICIs. Sodium-glucose cotransporter 2 (SGLT2i) are effective antidiabetic therapies associated reduced all-cause mortality and cardiovascular (CV) outcomes. Objective To evaluate prognostic value SGLT2i cardiotoxicity among Methods We performed retrospective analysis diagnosed cancer type DM (DM2) ICIs at our...

10.1186/s40959-023-00199-6 article EN cc-by Cardio-Oncology 2024-01-11

Background The scope of pericardial involvement in COVID-19 infection is unknown. We aimed to evaluate the prevalence, associates, and clinical impact hospitalized patients with COVID-19. Methods Results Consecutive underwent echocardiographic examination, irrespective indication, within 48 hours as part a prospective predefined protocol. Protocol included symptoms signs suggestive pericarditis, calculation modified early warning score, ECG assessment for effusion, left right ventricular...

10.1161/jaha.121.024363 article EN cc-by-nc-nd Journal of the American Heart Association 2022-03-21

We aim to assess changes in routine echocardiographic and longitudinal strain parameters patients recovering from Coronavirus disease 2019 during hospitalization at 3-month follow-up.Routine comprehensive echocardiography STE of both ventricles were performed for acute coronavirus (COVID-19) infection as part a prospective pre-designed protocol compared with ∼3 months after recovery 80 patients, using similar protocol. Significantly improved right ventricle (RV) fractional area change,...

10.1093/ehjci/jeab190 article EN European Heart Journal - Cardiovascular Imaging 2021-09-08

Abstract Background Immune checkpoint inhibitors (ICIs) have improved clinical outcomes for various types of cancer. However, their use is associated with cardiotoxicity. Left ventricular global longitudinal strain (LV-GLS) considered the standard care detecting early myocardial damage in patients treated anti-cancer drugs. routine LV-GLS limited by its time-consuming nature, and need expert cardiologists. AI-based applications may offer a cost-effective alternative to conventional methods....

10.1093/ehjci/jeae333.282 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

Abstract Background Left bundle branch block is a relatively common conduction disturbance that can occur as complication of transcatheter aortic valve implantation (TAVI) procedures. LBBB-induced cardiomyopathy (LBBB-CM) develops due to the mechanical dyssynchrony caused by abnormality. This lead adverse left ventricular remodeling over time, resulting in decline cardiac function. Nevertheless, data on iatrogenic LBBB TAVI lacking. Purpose To investigate prevalence, characteristics and...

10.1093/ehjci/jeae333.050 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

There are no comprehensive machine learning (ML) tools used by oncologists to assist with risk identification and referrals cardio-oncology. This study applies ML algorithms identify oncology patients at for cardiovascular disease cardio-oncology generate scores support quality of care.De-identified patient data were obtained from Vanderbilt University Medical Center. Patients breast, kidney, B-cell lymphoma cancers targeted. Additionally, the included who received immunotherapy drugs...

10.1093/ehjdh/ztad031 article EN cc-by-nc European Heart Journal - Digital Health 2023-05-08

ABSTRACT Background The increased mortality related to female gender in ST ‐segment elevation myocardial infarction ( STEMI ) patients treated with primary percutaneous coronary intervention PPCI has been reported from various patient cohorts and treatment strategies controversial results. In the present work, we evaluated impact of on in‐hospital complications among a specific subset consecutive managed solely by . Hypothesis Female is not an independent predicor for patients. Methods We...

10.1002/clc.22363 article EN Clinical Cardiology 2015-02-27
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